RF Safe argues that radiofrequency radiation (especially pulsed or modulated signals with low-frequency components) can alter local membrane potentials at nanometer scales where voltage-gated ion channel S4 sensors operate. It claims these shifts could change ion channel gating in immune cells, altering calcium and proton signaling, increasing oxidative stress, and promoting innate immune activation that may contribute to autoimmune-like inflammation. The piece presents a mechanistic causal chain and highlights heart and nerve tissue as potentially more susceptible due to high ion-channel density and mitochondrial content, but does not present new study data in the provided text.

This policy-focused paper contends that U.S. oversight of radiofrequency radiation from wireless technologies is outdated and insufficient, with exposure limits and testing approaches not aligned with modern long-term, chronic exposure scenarios. It emphasizes gaps in protections for children, pregnancy, vulnerable populations, workers, and wildlife, and describes limited monitoring, research, and enforcement capacity. The author proposes reforms to improve independent research, science-based limits, surveillance, and regulatory transparency.

This animal study examined whether paternal exposure to 4.9 GHz (5G) radiofrequency radiation affects male offspring in C57BL/6 mice. It reports increased anxiety-like behavior and reduced sperm quality in adult F1 males from exposed fathers, alongside reported LRGUK hypermethylation and reduced LRGUK expression in testes. The abstract reports no significant effects on depression-like behavior, learning/memory, or fertility across F1–F2 generations.

This animal study exposed adult male rats to 2.45 GHz electromagnetic radiation for 2 hours/day for one month and assessed testicular outcomes. The abstract reports that EMR exposure induced oxidative stress, increased inflammatory markers, and caused histological testicular injury. Alpha-lipoic acid supplementation was reported to mitigate these changes and restore several testicular proteins.

This multicenter case-control study in Iran (n=226) examined associations between mobile phone use and breast cancer outcomes in women. Reporting more than 60 minutes/day of phone conversations was associated with higher odds of confirmed invasive breast cancer and of being classified as a suspected case versus <10 minutes/day. The authors emphasize that the results do not establish causation and may be influenced by self-reported exposure and residual confounding, warranting cautious interpretation.

This narrative review discusses proposed non-thermal mechanisms by which chronic, low-intensity RF-EMR from ubiquitous wireless sources may affect male reproductive health. It highlights oxidative stress, mitochondrial dysfunction, impaired testosterone synthesis/steroidogenesis, and declines in sperm quality as reported outcomes. The authors argue that current SAR/thermal-based guidelines may not capture these endpoints and call for updated standards and precautionary measures.

This review summarizes studies reporting radiofrequency radiation (RFR)-associated changes in gene expression across biological systems. Reported affected genes relate to cellular stress responses, oxidative processes, apoptosis, DNA damage detection/repair, protein repair, and neural function regulation. The authors highlight reported gene expression effects at or below 0.4 W/kg SAR and argue this challenges current guideline assumptions, while noting that not all studies find significant effects.

This animal study examined whether prenatal exposure to 3.5 GHz radiofrequency radiation (2 hours/day) affects male reproductive outcomes later in life. Male rat offspring assessed at 12 months showed multiple adverse testicular and cellular findings in exposed groups versus sham controls, including impaired spermatogenesis markers, increased abnormal sperm morphology, increased DNA damage, and increased apoptosis, with full-gestation exposure generally most pronounced. The authors interpret the results as evidence of persistent reproductive toxicity from prenatal exposure and call for further mechanistic work and precautionary actions.

This conference paper uses COMSOL Multiphysics simulations to evaluate thermal and SAR-based exposure limits for modeled human skin exposed to terahertz radiation (0.1–5 THz). The authors report negligible temperature increases at power densities consistent with keeping SAR below 1.6 W/kg, but note that higher power densities can yield minimal heating while producing SAR values above recognized safety thresholds. They conclude that existing sub-THz standards are not directly transferable to the full THz band and call for updated guidelines, especially for prolonged exposure.

This experimental study examined how increased β ionizing radiation (31.3 μGy/h) and hypomagnetic conditions (0–1.5 μT) affect plant electrical signaling responses to stimuli. It reports enhanced electrical signals under increased ionizing radiation and weakened signals under near-null magnetic field conditions. The authors suggest these effects may be mediated by changes in reactive oxygen species involved in stress signaling.

This paper evaluates and critiques 12 WHO-commissioned systematic reviews and meta-analyses on RF-EMF health effects across outcomes including cancer and reproductive endpoints. It argues that serious methodological flaws and limitations in the WHO reviews prevent them from providing assurance of safety for cell phones and other wireless devices. The authors highlight reported evidence in the animal cancer review (high certainty for heart schwannomas; moderate certainty for brain gliomas) and describe dose-related adverse effects on male fertility and reproductive outcomes, including at exposure levels below current ICNIRP thresholds.

The review states there is no scientific consensus on whether Wi‑Fi (2.4/5 GHz) contributes to Alzheimer's disease through oxidative stress, and that existing results are mixed and inconclusive. It discusses an indirect analysis linking oxidative-stress-responsive genes after 2.4 GHz exposure with genes associated with Alzheimer's disease. The authors suggest chronic exposure could affect regulation of neurodegeneration-related genes (e.g., GSK3B, APOE), while emphasizing that a direct relationship has not been demonstrated and more research is needed.

This in vitro study used LC-MS metabolomics to assess how continuous versus intermittent RF-EMF irradiation affects mouse Leydig (TM3) and spermatogonia (GC-1) cells. The authors report stronger metabolic disturbances in TM3 cells under continuous exposure, including changes in amino acid and glutathione-related pathways, while intermittent exposure mainly affected fatty acyl and purine-related metabolism. GC-1 cells were reported to be less sensitive, and ADP changes were proposed as a potential metabolic signature. The authors interpret these metabolic disturbances as suggesting potential reproductive health risks.

This 2025 review summarizes historical and modern literature on how bacteria may adapt to radiofrequency electromagnetic fields from common sources such as mobile phones and Wi-Fi. It argues that RF-EMF exposure can influence bacterial survival mechanisms and could potentially compromise therapeutic interventions by promoting increased resistance. The authors frame these possibilities as a public health concern and call for continued research and precaution.

This narrative review examines research on radiofrequency electromagnetic radiation (RF-EMR) from mobile towers and its potential association with genetic damage and genetic polymorphism in humans, with an emphasis on India. The abstract states that RF-EMR exposure may affect genetic material and suggests a link between EMR exposure and genetic damage, with possible implications for cancer risk and cell death. It also highlights that genetic polymorphisms may modify susceptibility and calls for further research to clarify health impacts.

This review compares two epidemiologic studies of radio-frequency radiation (RFR) exposure among military personnel with overlapping patient groups. One study reported a statistically significant increase in cancer among exposed individuals, while the other did not, which the review attributes to a smaller sample size. The review highlights similar cancer patterns across both studies, including a high proportion of hematolymphoid cancers and earlier onset among exposed individuals, and interprets these similarities as evidence of carcinogenic effects.

This randomized controlled animal study examined chronic 35.5 GHz millimeter wave exposure in male Wistar rats (2 hours/day for 60 days) compared with control and sham groups. The exposed group showed reduced sperm count and viability along with testicular histopathological changes. Oxidative stress markers shifted toward increased lipid peroxidation and reduced antioxidant defenses, and comet assay results indicated increased DNA damage.

This article summarizes a webinar series and frames pesticides and wireless radiation as concurrent environmental health crises affecting ecosystems and public health. It asserts that evidence is building for adverse effects of EMF/wireless radiation in humans, animals, and bees, including “high-certainty links” between RF radiation and tumors in brain and heart nerves. It also suggests potential synergy between chemical and EMF exposures impacting bee hive productivity and argues for precautionary policy and stronger exposure guidelines.

This prospective cohort study followed 105 neonates/infants for one year and measured household RF-EMF using a selective radiation meter, categorizing exposure into tertiles. Higher household RF-EMF exposure was associated with lower ASQ-3 neurodevelopmental scores, particularly in motor and problem-solving domains, and higher odds of monitor/refer classifications for fine motor and problem-solving. The abstract notes these associations persisted after adjustment for low birth weight, though exposure was measured at a single time point and key confounders (e.g., prenatal phone use, parental interaction) were not assessed.

This narrative article examines how opposing views formed regarding health and biological effects of electromagnetic radiation, focusing on ELF and RF exposures. It highlights historical controversies (e.g., childhood leukemia and ELF fields) and disputes over thermal versus non-thermal effects and reliance on SAR. The author argues that social and institutional factors, including industry influence, shaped interpretation and public discourse around EMF safety.

This case-control genetic association study in men from West Bengal, India examined variants in meiotic regulator genes (SPO11, RNF212, SYCP3) alongside reported exposure to electronic (electromagnetic) radiation as risk factors for azoospermia. It reports that genetic variants were associated with increased azoospermia risk, and that risk was higher among men aged 30+ who were also exposed to electromagnetic radiation. The authors conclude that EMF exposure may exacerbate fertility impairment in genetically predisposed men.

This conference paper uses numerical simulations to evaluate near-field exposure and thermal effects in a detailed human head model from a realistic 5G mobile phone operating at 26 GHz. The preliminary modeling suggests moderate, localized temperature increases in superficial tissues. The authors emphasize the need for higher-resolution models, refined tissue segmentation, longer exposure durations, and varied phone placements to better characterize potential impacts.