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Electromagnetic fields from mobile phones: A risk for maintaining energy homeostasis?

Research RF Safe Research Library Jan 1, 2025

This narrative review discusses low-intensity RF-EMF exposure, primarily from mobile phones, with a focus on thermoregulation and energy homeostasis. It reports that many rodent studies at 900 MHz describe cold-like thermoregulatory and behavioral responses and molecular findings suggestive of WAT browning, while BAT transcriptional changes typical of cold exposure were not observed. The authors indicate short-term adaptations may not disrupt homeostasis, but emphasize uncertainty about long-term consequences and call for further research, including at 5G-relevant frequencies.

Human achromatic flickers and phosphenes thresholds under extremely low frequency electric stimulations

Research RF Safe Research Library Jan 1, 2025

This study estimated thresholds and locus for human phosphene perception during non-invasive transcranial alternating current stimulation at 20, 50, 60, and 100 Hz. Perception depended significantly on stimulation intensity, with the lowest threshold at 20 Hz and no reported phosphenes at 100 Hz. The authors report dosimetry consistent with a retinal origin and frame the findings as relevant for informing cautious ELF exposure limits in safety guidelines.

Influence of geomagnetic disturbances on myocardial infarctions in women and men from Brazil

Research RF Safe Research Library Jan 1, 2025

This ecological analysis used a public health database of myocardial infarction admissions in São José dos Campos, Brazil (1998–2005) and categorized geomagnetic activity using the planetary Kp index. The abstract reports a higher relative frequency of MI admissions during disturbed geomagnetic conditions compared with quiet periods, with a stronger association in women. Unsupervised k-means clustering reportedly supported the sex-specific pattern.

Potential Impacts of Radiofrequency Electromagnetic Fields on the Central Nervous System, Brain Neurotransmitter Dynamics and Reproductive System

Research RF Safe Research Library Jan 1, 2025

This review discusses potential impacts of radiofrequency electromagnetic fields from technologies such as Wi‑Fi and mobile phones on the central nervous system, neurotransmitter dynamics, and reproductive health. It describes proposed mechanisms including oxidative stress, thermal effects, altered neurotransmitter activity, ion channel changes, and neuronal apoptosis, while acknowledging conflicting evidence. The authors note that Wi‑Fi RF exposure has not been confirmed to exceed safety guidelines but argue that updated standards and long-term studies are needed, particularly for children/adolescents and in the context of expanding technologies such as 5G.

Electromagnetic wireless remote control of mammalian transgene expression

Research RF Safe Research Library Jan 1, 2025

This animal proof-of-concept study describes an engineered nanoparticle–cell interface (EMPOWER) enabling wireless regulation of transgene expression using a 1-kHz magnetic field. Chitosan-coated multiferroic nanoparticles reportedly generate intracellular ROS that activates KEAP1/NRF2 biosensors connected to ROS-responsive promoters. In a mouse model of type 1 diabetes, implanted engineered cells expressing an EMPOWER-controlled insulin system reportedly normalized blood glucose in response to a weak magnetic field.

Effects of radiofrequency electromagnetic field exposure on cancer in laboratory animal studies, a systematic review

Research RF Safe Research Library Jan 1, 2025

This systematic review evaluated RF EMF exposure and cancer outcomes in experimental animals, including chronic cancer bioassays and tumor-promotion designs. Across 52 included studies, the authors report high certainty of evidence for increased malignant heart schwannomas and gliomas in male rats, and moderate certainty for increased risks of several other tumor types. Many other organ systems showed no or minimal evidence of carcinogenic effects, and the authors note challenges in translating animal findings to human risk assessment due to exposure and mechanistic uncertainties.

Determining the relationship between mobile phone network signal strength and RF-EMF exposure: protocol and pilot study to derive conversion functions

Research RF Safe Research Library Jan 1, 2025

This protocol and pilot study evaluated whether smartphone signal strength indicators can be converted into RF-EMF exposure estimates using derived formulas and regression models. The study reports a positive log-linear association between LTE RSSI and far-field (base station) exposure aggregated by location, while handset-related exposure at the ear and chest during data transmission showed negative log-linear trends with improving signal quality. The authors conclude the ETAIN 5G-Scientist app may support large-scale RF-EMF exposure assessment, but emphasize the need for more data to improve accuracy and address uncertainties in individual measurements.

Use of Electrical Household Appliances and Risk of All Types of Tumours: A Case-Control Study

Research RF Safe Research Library Jan 1, 2025

This multi-hospital case-control study (n=316) examined associations between use of common household electrical appliances emitting ELF EMF and tumour risk. Most devices showed below-unity odds ratios, while computer screen and microwave oven use showed slightly increased odds with wide confidence intervals. Proximity to electricity transformer stations was associated with higher tumour odds, whereas proximity to powerlines was not.

Effect of electromagnetic field radiation on transcriptomic profile and DNA methylation level in pig conceptuses during the peri-implantation period

Research RF Safe Research Library Jan 1, 2025

This in vitro study exposed pig conceptuses (days 15–16 of pregnancy) to 50 Hz ELF-EMF for 2 hours and assessed transcriptomic and DNA methylation changes. The authors report altered expression of 21 protein-coding transcripts and an approximately 16-fold increase in genomic DNA methylation, with promoter methylation changes in several named genes. They conclude ELF-EMF interacts with gene expression and DNA methylation processes during early development and call for further safety research.

RF-EMF exposure assessment with add-on uplink exposure sensor in different microenvironments in seven European countries

Research RF Safe Research Library Jan 1, 2025

This exposure assessment study introduces a cost-efficient add-on sensor attached to a smartphone to quantify auto-induced uplink RF-EMF transmission across 100–6000 MHz in multiple microenvironments. Activity-based surveys were conducted in seven European countries under non-user, maximum downlink, and maximum uplink scenarios. Reported power levels were lowest for non-user scenarios and higher during active use, with variation by country, urbanization, and setting. The authors frame the work as supporting future epidemiological research and planned validation against other tools.

The Effect of Proximity Sensor & Grip Sensor Use on Specific Absorption Rate (SAR) in Smartphones

Research RF Safe Research Library Jan 1, 2025

This engineering study examined how smartphone proximity and grip sensors affect SAR during LTE and 5G NR operation in a 3D measurement environment. The abstract reports that enabling these sensors reduces SAR relative to being turned off, with reductions varying by sensor and frequency. The authors attribute the reduction to sensor-driven power management and transmission power adjustment.

Repeated Head Exposures to a 5G-3.5 GHz Signal Do Not Alter Behavior but Modify Intracortical Gene Expression in Adult Male Mice

Research RF Safe Research Library Jan 1, 2025

This animal study examined repeated asymmetrical head exposure to a 5G-modulated 3.5 GHz signal in adult male mice for six weeks. It reports no significant changes in locomotion, anxiety, or object-based memory performance under the tested conditions. However, it found statistically significant but limited cortical gene expression changes (<1% of expressed genes), including enrichment for glutamatergic synapse-related genes and lateralized differences involving mitochondrial genome-encoded genes. The authors caution that potential health risks from these intracortical transcriptomic modifications should not be downplayed and note uncertainties about longer exposures and other populations.

5G Radiofrequency Exposure Reduces PRDM16 and C/EBP � mRNA Expression, Two Key Biomarkers for Brown Adipogenesis

Research RF Safe Research Library Jan 1, 2025

This animal study exposed juvenile and young adult Wistar rats to 5G (3.5 GHz) or 2G (900 MHz) radiofrequency fields (1.5 V/m) for 1–2 weeks and measured brown adipose tissue-related gene expression by RT-qPCR. The abstract reports significant downregulation of PRDM16 and C/EBP mRNA after 5G exposure, while UCP1-dependent thermogenesis markers were not significantly changed at the transcriptional level. The authors interpret these findings as a potential partial disruption of brown adipocyte differentiation and raise EMF safety concerns, while calling for further confirmatory research.

Enhancement Effect of Static Magnetic Field on Bactericidal Activity

Research RF Safe Research Library Jan 1, 2025

This in vitro study reports that a static magnetic field (SMF) combined with paramagnetic calcium-polypyrrole nanoparticles (Ca-PPy) markedly increases bactericidal activity against E. coli and S. aureus. The authors attribute the enhanced killing to increased reactive oxygen species generation and associated membrane disruption, with computational analysis suggesting altered radical-pair transitions under magnetic fields. The abstract frames SMF as potentially biocompatible and useful for bactericidal applications, while also noting broader biological impacts of electromagnetic fields.

Electric and Magnetic Field Technologies in Agriculture: Plant Responses, Experimental Limitations, and Future Directions

Research RF Safe Research Library Jan 1, 2024

This narrative review discusses how electric and magnetic field technologies are applied in agriculture and how plants may respond. It proposes a model to explain potential mechanistic convergence between electric and magnetic field effects. The review highlights several suggested mechanisms, including membrane permeability changes, reactive oxygen species/antioxidant responses, altered ion transport, and DNA/gene expression changes.

Prospective cohort study on non-specific symptoms, cognitive, behavioral, sleep and mental health in relation to electronic media use and transportation noise among adolescents (HERMES): study protocol

Research RF Safe Research Library Jan 1, 2024

This protocol describes the third wave of the HERMES prospective adolescent cohort in Switzerland, with follow-up every four months and at one year. The study will assess electronic media use, modeled RF-EMF and transportation noise exposures, and a range of outcomes including cognition, behavior, sleep, mental health, and non-specific symptoms. A subsample will undergo personal RF-EMF measurements and accelerometer-based sleep/physical activity tracking.

Effect of Repeated Exposure to Complexly Organized Electromagnetic Radiation on the Rat Behavior in the "Open Field" Test

Research RF Safe Research Library Jan 1, 2024

This animal study examined repeated pulsed-modulated RF exposure (1–4 GHz; total pulse power density 300 μW/cm2) in male and female Wistar rats and assessed behavior using the open field test. The abstract reports stress reactions and long-term memory impairment in some rats, with females described as more sensitive than males. Reported effects were transient, with behavior returning to baseline within 1.5–2 months after exposure stopped. The authors suggest potential concern for constant exposure scenarios, though this is not directly evaluated in humans here.

Effects of GSM modulated radio-frequency electromagnetic radiation on permeability of blood-brain barrier in male & female rats

Research RF Safe Research Library Jan 1, 2016

This rat study examined whether pulse-modulated 900 MHz and 1800 MHz RF exposure affects blood-brain barrier permeability using Evans blue dye. The abstract reports increased permeability in male rats at both frequencies (stronger at 1800 MHz) and in female rats at 900 MHz but not at 1800 MHz. The authors suggest mobile-phone-like RF exposure could increase blood-brain barrier permeability under non-thermal conditions, while noting that further mechanistic studies are needed.

Effects of radiofrequency radiation exposure on blood-brain barrier permeability in male and female rats

Research RF Safe Research Library Jan 1, 2011

This rat study tested whether acute exposure to 0.9 and 1.8 GHz continuous-wave radiofrequency radiation alters blood-brain barrier permeability. Using Evans-blue/albumin as a tracer, the authors report no BBB leakage in exposed female rats but a significant increase in albumin in exposed male rat brains versus sham. The authors interpret this as suggesting BBB/vascular permeability changes in males at SAR levels stated to be below international limits.

20 kHz Magnetic Field Emission of Induction Cooking Heaters

Research RF Safe Research Library Jan 1, 2004

This exposure assessment measured 20 kHz magnetic field leakage from induction cooking heaters across four models and compared results with ICNIRP general public limits. The maximum reported magnetic flux density was 16 µT at a specified measurement point using two S-type pans. Field leakage depended on pan size and configuration, and finite element modeling was reported to align closely with measurements.

Physics and biology of mobile telephony

Research RF Safe Research Library Jan 1, 2000

This review argues that current mobile-telephony safety guidelines address excessive microwave heating but may not account for potential non-thermal influences of low-intensity, pulsed radiation. It highlights an asserted oscillatory similarity between pulsed microwave signals and certain electrochemical activities in humans as a reason for concern. While acknowledging uncertainty about health consequences, it notes reported consistencies between some non-thermal effects and neurological problems described by some users and people with long-term base-station exposure.

Evaluation of Electrochemical Information Transfer System: I . Effect of Electric Fields on Living Organisms

Research RF Safe Research Library Jan 1, 1976

This 1976 animal study evaluated the effects of weak ELF electric fields similar to those associated with Project Seafarer on mice. The abstract reports that electric field exposure acted as a biological stressor, with effects involving the central nervous and endocrine systems. It is presented as part of broader research assessing potential physiological changes from high-power, low-frequency electromagnetic communication systems.

Bibliography of reported biological phenomena ("effects") and clinical manifestations attributed to microwave and radio-frequency radiation

Research RF Safe Research Library Jan 1, 1971

This item is a bibliography of reported biological phenomena and clinical manifestations attributed to radio-frequency and microwave radiation. It compiles over 2000 references published up to June 1971, with supplemental listings through Nov. 21, 1971, and gives particular attention to reported effects in humans. The abstract does not describe any systematic synthesis or conclusions about health effects.

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