Archive

This in vitro study describes a microfluidic device integrated with a radiofrequency exposure system to enable on-chip monitoring of cellular responses under a 1.8 GHz field. Using human amniotic epithelial cells, the authors report field-intensity-associated increases in protrusions/filopodia, changes in…

This preprint describes an in vitro bioreactor-based system to test whether electromagnetic/electrical stimulation affects extracellular vesicles (EVs). Using proteomics and single-vesicle flow cytometry, the authors report that stimulation at physiological current amplitudes can modulate EV content in a…

This pilot swine study evaluated whether non-contact proprietary induction sensors in a Mu-metal/copper mesh helmet can measure endogenous neuronal EMF signals before and after controlled cortical impact traumatic brain injury. The authors report that swine EMF recordings were distinguishable from room noise and…

This animal and laboratory study evaluated extremely low-frequency electromagnetic stimulation (ELF-EMS) in a rodent ischemia-reperfusion stroke model and related in vitro/slice experiments. The authors report improved neurological and behavioral outcomes, increased neuronal survival, and reduced glial/microglial…

This in vitro study tested ELF-EMF exposure in U87 and U251 glioblastoma cell lines and assessed apoptosis, cell-cycle distribution, cell size, and mRNA expression of cell-cycle genes. The authors report higher apoptosis induction and increased G2/M arrest in U87 compared with U251, alongside increased U87 cell size…

This paper reviews literature from 1980–2023 on the role of electromagnetic fields as a therapy for traumatic brain injury and brain neuropathology. It reports that existing findings suggest electromagnetic therapy may be a promising non-invasive treatment approach. The authors emphasize that current evidence is…

This in vitro study tested whether a 50 Hz, 20 mT extremely low-frequency electromagnetic field (ELF-EMF) enhances the cytotoxic effects of doxorubicin (DOX) in the MCF-7 breast cancer cell line. The authors report that combining ELF-EMF with low-dose DOX reduced cell viability at lower DOX concentrations than DOX…

This paper presents the protocol for the EMAGINE multicenter, double-blind, randomized, sham-controlled trial testing an extremely low-frequency, low-intensity, frequency-tuned electromagnetic field therapy (ENTF) after subacute ischemic stroke. Participants will start active or sham treatment 4–21 days post-stroke,…

This paper describes a literature-mining analysis of more than 30,000 EMF-related publications to extract genes, diseases, and molecular mechanisms linked to EMF exposure across six EMF subsets. The authors report identifying 3,653 unique disease MeSH terms and 9,966 unique genes, including 4,340 human genes. The…

This engineering/simulation study evaluates RF applicator array designs for Thermal Magnetic Resonance (ThermalMR), which combines MRI with RF hyperthermia for brain tumor theranostics. Using EMF and temperature simulations at 7.0 T, 9.4 T, and 10.5 T, hybrid loop+SGBT dipole arrays are reported to provide superior…

This single-site feasibility trial evaluated repeated 90-minute amplitude-modulated EMF exposure (AutEMdev) in 66 patients with advanced hepatocellular carcinoma. The primary focus was safety and hemodynamic variability during exposure, with exploratory outcomes including quality of life, survival, and tumor…

This study optimized cacao bean fermentation for the CCN 51 clone using native microbial species and applied magnetic fields, varying field density, exposure time, and inoculum concentration. It reports improved yield and bean quality versus a no-magnetic-field control at an optimized condition (5 mT, 22.5 min, 1.6%…

This in vitro study compared continuous versus intermittent 16 Hz ELF-PEMF exposure strategies in osteoprogenitor (SCP-1) cells. Intermittent exposure (10 min every 8 h) was reported to enhance cell numbers and osteogenic function relative to continuous daily exposure (30 min every 24 h). The authors report increased…

This feasibility study reports numerical modeling and HFSS simulations of a portable meander line antenna intended to deliver repeated electromagnetic field stimulation at 64 MHz for potential Alzheimer's disease treatment. Using two numerical head phantoms, the authors simulated E/H fields and SAR with a 50-W input…

This study examined whether exposing maize seeds to electromagnetic fields (23, 70, 118 μT) for 15 days alters physicochemical properties of starch isolated from the resulting grains. SEM and X-ray diffraction results suggest starch morphology and orthorhombic crystalline structure were largely unchanged, though…

This paper reports a PubMed and Google Scholar-based review of EMF research related to brain pathology, with emphasis on ischemic and traumatic brain injury. It provides a critical overview of the state of the art and describes the authors’ experimental and ongoing studies. The authors conclude that EMF applications…

This study describes a magnetofection system using electromagnetic field (EMF) co-stimulation with iron oxide nanoparticles (IONPs) to deliver miR-21. The authors report increased transfection efficiency and promotion of osteogenesis and angiogenesis in BMSCs and HUVECs, with downstream application to…