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Repeated Head Exposures to a 5G-3.5 GHz Signal Do Not Alter Behavior but Modify Intracortical Gene Expression in Adult Male Mice

Research RF Safe Research Library Jan 1, 2025

This animal study examined repeated asymmetrical head exposure to a 5G-modulated 3.5 GHz signal in adult male mice for six weeks. It reports no significant changes in locomotion, anxiety, or object-based memory performance under the tested conditions. However, it found statistically significant but limited cortical…

The CB1R of mPFC is involved in anxiety-like behavior induced by 0.8/2.65 GHz dual-frequency electromagnetic radiation

Research RF Safe Research Library Jan 1, 2025

This animal study reports that dual-frequency RF EMR exposure (0.8/2.65 GHz, 4 W/kg) induced anxiety-like behavior in mice. It also reports reduced CB1R and endocannabinoid levels in the mPFC and altered endocannabinoid system markers in the BLA. CB1R overexpression or knockdown in the mPFC reportedly decreased or…

Histomorphometry and Sperm Quality in Male Rats Exposed to 2.45 GHz Wi-Fi

Research RF Safe Research Library Jan 1, 2025

This animal study exposed adult male rats to 2.45 GHz Wi‑Fi from an active router for 4 or 24 hours daily over eight weeks and assessed reproductive organ histology and sperm parameters. The authors report histological changes in testes and epididymis, multifocal atypical hyperplasia in seminal vesicles, reduced…

A Novel Design of a Portable Birdcage via Meander Line Antenna (MLA) to Lower Beta Amyloid (Aβ) in Alzheimer's Disease.

Research RF Safe Research Library Jan 1, 2025

This translational engineering paper describes a portable RF birdcage/meander line antenna concept for repeated electromagnetic field stimulation at 64 MHz aimed at lowering amyloid-beta in Alzheimer’s disease. The abstract reports prior in vitro findings in primary human brain cultures showing reduced secreted Aβ-42…

The use of different exposure metrics in the research about the health impacts of electromagnetic fields

Research RF Safe Research Library Jan 1, 2024

This policy brief focuses on how RF-EMF exposure should be quantified in health research, emphasizing the role of near-field sources and proposing cumulative dose (J/kg/day) as a health-relevant metric. It reports mean cumulative dose estimates of 0.29 J/kg/day for the whole body and 0.81 J/kg/day for the brain. The…

Risk factors of congenital anomalies of the kidney and urinary tract (CAKUT): Exposure to mobile phones during pregnancy.

Research RF Safe Research Library Jan 1, 2024

This case-control study (57 CAKUT cases, 57 controls) evaluated multiple risk factors for CAKUT, including mobile phone-related EMF exposure during pregnancy. Longer maternal daily call time and higher effective SAR (SAR × call time) were reported to be associated with increased CAKUT risk, while phone proximity when…

Transcriptional response of primary hippocampal neurons following exposure to 3.0 GHz radiofrequency electromagnetic fields.

Research RF Safe Research Library Jan 1, 2024

This in vitro study exposed rat primary hippocampal neurons to 3.0 GHz continuous-wave RF-EMF under low-SAR (minimal heating) and high-SAR (thermal) conditions and measured transcriptional responses by RNA sequencing. Twenty genes were significantly upregulated only in the high-SAR condition associated with a ~3.6°C…

Effects of Head-Only Exposure to 900 MHz GSM Electromagnetic Fields in Rats: Changes in Neuronal Activity as Revealed by c-Fos Imaging without Concomitant Cognitive Impairments.

Research RF Safe Research Library Jan 1, 2024

This rat study used a head-only 900 MHz GSM exposure system to assess brain activity changes via c-Fos imaging and to test spatial memory performance. Acute exposure (2 h) was associated with dose-dependent, region-specific increases in c-Fos expression, while repeated pre-training exposures were associated with…

A Deep Learning Framework for Evaluating the Over-the-Air Performance of the Antenna in Mobile Terminals.

Research RF Safe Research Library Jan 1, 2024

This engineering study presents RTEEMF-PhoneAnts, a convolutional neural network framework to predict mobile phone antenna metrics (EIRP, TRP, and SAR) from near-field EMF distributions. Using a dataset of 7000 mobile phone models, the authors report statistical validation for predicted SAR/TRP and a validation…

Exposure to Radiofrequency Induces Synaptic Dysfunction in Cortical Neurons Causing Learning and Memory Alteration in Early Postnatal Mice.

Research RF Safe Research Library Jan 1, 2024

This animal study examined 1850 MHz RF-EMF exposure (SAR 4.0 W/kg) in early postnatal mice and assessed synaptic and behavioral outcomes. The abstract reports reductions in dendritic spine maturation markers, decreases in PSD-95 puncta, inhibited neurite outgrowth, and downregulation of synapse-related genes in…

Improved assessment of radiofrequency electromagnetic field power deposition near orthopaedic device using a bone-inclusive ASTM phantom under 1.5T and 3T MRI.

Research RF Safe Research Library Jan 1, 2024

This engineering/simulation study proposes a bone-inclusive ASTM phantom to improve assessment of RF power deposition near orthopaedic implants during 1.5 T and 3 T MRI. Using numerical simulations across multiple implant families, the authors report better correlation of peak 1 g SAR near implants with anatomically…

Sex-dependent impact of perinatal 5G electromagnetic field exposure in the adolescent rat behavior.

Research RF Safe Research Library Jan 1, 2023

This animal study examined daily perinatal 5G EMF exposure in rats at the ICNIRP whole-body public exposure limit (maternal SAR 0.07 W/kg) from gestational day 8 to post-natal day 21. The authors report a 1-day delay in incisor eruption in both sexes and sex-dependent changes in stereotyped behavior in the open field…

Numerical Modeling and Computer Simulation of a Meander Line Antenna for Alzheimer's Disease Treatment, a Feasibility Study.

Research RF Safe Research Library Jan 1, 2023

This feasibility study reports numerical modeling and HFSS simulations of a portable meander line antenna intended to deliver repeated electromagnetic field stimulation at 64 MHz for potential Alzheimer's disease treatment. Using two numerical head phantoms, the authors simulated E/H fields and SAR with a 50-W input…

The effects of RF coils and SAR supervision strategies for clinically applicable nonselective parallel-transmit pulses at 7 T.

Research RF Safe Research Library Jan 1, 2023

This engineering study evaluated how different 7T parallel-transmit head coils and SAR supervision strategies affect nonselective pTx pulse design for a 3D-MPRAGE sequence. It reports that FOCUS pulses were more robust than universal pulses when applied across different coils, and that FOCUS inversion pulses…

An Out-of-Phase Wireless Power Transfer System for Implantable Medical Devices to Reduce Human Exposure to Electromagnetic Field and Increase Power Transfer Efficiency.

Research RF Safe Research Library Jan 1, 2022

This engineering study proposes an out-of-phase coupled wireless power transfer system for implantable medical devices intended to reduce electromagnetic field exposure in the tissue region between transmitting and receiving coils. The authors report, via simulation and measurements, lower EMF and higher power…

Wearable Antennas for Sensor Networks and IoT Applications: Evaluation of SAR and Biological Effects.

Research RF Safe Research Library Jan 1, 2022

This in vitro study evaluated SAR and erythrocyte membrane stability during exposure to a fully textile wearable antenna at 2.41 GHz under realistic (6.3 mW) and conservative (450 mW) input power conditions. It reports 1 g average SARs of 0.5758 W/kg and 41.13 W/kg, respectively. For membrane stability at 6.3 mW,…

EMF Antenna Exposure on a Multilayer Human Head Simulation for Alzheimer Disease Treatments.

Research RF Safe Research Library Jan 1, 2022

This study uses HFSS/EMPro simulations to model a 64 MHz antenna exposure on a multilayer human head to match parameters previously used in neuronal culture experiments. The simulations report achieving up to 0.6 W/kg maximum SAR and approximately 0.4–0.6 W/kg across head layers with a 1 A peak current pulse. The…

Modelling and Evaluation of the Absorption of the 866 MHz Electromagnetic Field in Humans Exposed near to Fixed I-RFID Readers Used in Medical RTLS or to Monitor PPE.

Research RF Safe Research Library Jan 1, 2021

This study modelled SAR in humans near fixed multi-antenna UHF RFID readers operating at 866 MHz, representing RTLS and PPE-monitoring use scenarios. The modelling suggests that at 5 cm distance, SAR may warrant consideration against international exposure limits aimed at preventing thermal effects when effective…

Exposure to long-term evolution radiofrequency electromagnetic fields decreases neuroblastoma cell proliferation via Akt/mTOR-mediated cellular senescence.

Research RF Safe Research Library Jan 1, 2021

This in vitro study examined LTE RF-EMF exposure effects on SH-SY5Y neuroblastoma cells. The authors report reduced cell proliferation and a G0/G1 cell-cycle delay after 1760 MHz exposure at 4 W/kg for 4 hr/day over 4 days. They report no marked DNA damage signal (γH2AX) and no apoptosis activation, but increased…

Exposure to RF-EMF Alters Postsynaptic Structure and Hinders Neurite Outgrowth in Developing Hippocampal Neurons of Early Postnatal Mice.

Research RF Safe Research Library Jan 1, 2021

This animal and primary neuron culture study exposed early postnatal mice to whole-body RF-EMF (SAR 4.0 W/kg) for 5 hours/day from P1 to P28. The authors report reductions in dendritic spine measures (notably mushroom-type spines), decreased glutamate receptor expression in mushroom-type spines, and lower BDNF…

Activation of matrix metalloproteinases and FoxO3a in HaCaT keratinocytes by radiofrequency electromagnetic field exposure.

Research RF Safe Research Library Jan 1, 2021

This in vitro study exposed HaCaT human keratinocytes to 1760 MHz RF-EMF (SAR 4.0 W/kg; 2 h/day for 4 days). The authors report increased intracellular ROS and increased expression/activity of several matrix metalloproteinases, along with increased phosphorylation of FoxO3a and ERK1/2. Cell growth/viability and…

Microtubular structure impairment after GSM-modulated RF radiation exposure.

Research RF Safe Research Library Jan 1, 2020

This in vitro study exposed V79 cells to 915 MHz GSM-modulated RF radiation for 1–3 hours at 10–30 V/m (average SARs reported as 0.23–1.6 W/kg). The authors report that 3-hour exposure altered microtubule structure across all tested field strengths and reduced cell growth on the third post-exposure day. They conclude…

Effects of pulse-modulated radiofrequency magnetic field (RF-EMF) exposure on apoptosis, autophagy, oxidative stress and electron chain transport function in human neuroblastoma and murine microglial cells.

Research RF Safe Research Library Jan 1, 2020

This in vitro study exposed murine microglial (N9) and human neuroblastoma (SH-SY5Y) cells to ELF-modulated 935 MHz RF-EMF at 4 W/kg for 2 or 24 hours. The authors report no changes in apoptosis, cell viability, or AIF across conditions. They report increased ATG5 after 24 hours and a transient glutathione increase…

Supervised Machine Learning Algorithms for Bioelectromagnetics: Prediction Models and Feature Selection Techniques Using Data from Weak Radiofrequency Radiation Effect on Human and Animals Cells.

Research RF Safe Research Library Jan 1, 2020

This paper develops supervised machine-learning prediction models to analyze potential impacts of weak RF-EMF on human and animal cells using extracted laboratory experimental data from prior publications. Data from 300 peer-reviewed papers (1127 experimental case studies) were used with feature selection and…

Wideband Self-Grounded Bow-Tie Antenna for Thermal MR.

Research RF Safe Research Library Jan 1, 2020

This engineering study designed and tested a compact wideband self-grounded bow-tie RF antenna module for a whole-body 7.0 T MRI system, aiming to enable 1H/19F MRI, MR thermometry, and broadband RF thermal intervention. The authors report validated B1 efficiency measurements and phantom-based heating experiments…

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