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Showing results for: membrane

Thermodynamic Considerations on the Biophysical Interaction between Low-Energy Electromagnetic Fields and Biosystems.

Research RF Safe Research Library Jan 1, 2024

This paper presents a thermodynamic model intended to explain how extremely low-frequency electromagnetic fields (ELF-EMFs) may interact with cells. The authors propose that ELF-EMFs directly interfere with the cellular membrane, producing biological responses linked to energy conversion and changes in flows across…

Enhancement of Fungal Enzyme Production by Radio-Frequency Electromagnetic Fields.

Research RF Safe Research Library Jan 1, 2022

This in vitro study examined whether a 2 GHz RF-EMF exposure could enhance enzyme production in a filamentous fungus. A 10-minute exposure was reported to increase extracellular total protein and α-amylase activity in culture media versus controls, alongside increased α-amylase mRNA and changes consistent with…

Wearable Antennas for Sensor Networks and IoT Applications: Evaluation of SAR and Biological Effects.

Research RF Safe Research Library Jan 1, 2022

This in vitro study evaluated SAR and erythrocyte membrane stability during exposure to a fully textile wearable antenna at 2.41 GHz under realistic (6.3 mW) and conservative (450 mW) input power conditions. It reports 1 g average SARs of 0.5758 W/kg and 41.13 W/kg, respectively. For membrane stability at 6.3 mW,…

Translocation of silica nanospheres through giant unilamellar vesicles (GUVs) induced by a high frequency electromagnetic field.

Research RF Safe Research Library Jan 1, 2021

This in vitro study used giant unilamellar vesicles (GUVs) to examine effects of an 18 GHz electromagnetic field on membrane behavior. The authors report increased membrane permeability after exposure, inferred from internalisation of 23.5 nm hydrophilic silica nanospheres. Complementary molecular dynamics…

Nonionizing Electromagnetic Field: A Promising Alternative for Growing Control Yeast.

Research RF Safe Research Library Jan 1, 2021

This laboratory study examined radiofrequency EMF exposure between 1 and 5.9 GHz as a method to control yeast growth relevant to food spoilage. The authors report reduced yeast viability at all tested frequencies and note that antenna-to-sample distance affected the outcome. Electron microscopy findings are described…

Non-thermal membrane effects of electromagnetic fields and therapeutic applications in oncology.

Research RF Safe Research Library Jan 1, 2021

This review examines temperature-independent (non-thermal) effects of RF and microwave electromagnetic fields, emphasizing antiproliferative effects relevant to oncology. It summarizes preclinical and clinical literature on conventional RF hyperthermia and amplitude-modulated RF hyperthermia and argues that evidence…

Evaluation of the neuroprotective effects of Vitamin E on the rat substantia nigra neural cells exposed to electromagnetic field: An ultrastructural study.

Research RF Safe Research Library Jan 1, 2021

This rat study exposed animals to a 50 Hz, 3 mT electromagnetic field and assessed oxidative stress markers and substantia nigra ultrastructure. EMF exposure was associated with higher lipid peroxidation (MDA), lower SOD activity, and TEM-detected changes in nucleus/nuclear membrane and myelin sheath. Vitamin E…

Global gene expression changes reflecting pleiotropic effects of Irpex lacteus induced by low--intensity electromagnetic field.

Research RF Safe Research Library Jan 1, 2019

This laboratory study used RNA-seq to examine how low-intensity electromagnetic field (LI-EMF) exposure affects global gene expression in the fungus Irpex lacteus. Thousands of differentially expressed genes were reported immediately after exposure, with fewer changes after 3 h and 6 h recovery, and a subset of genes…

The effect of a high frequency electromagnetic field in the microwave range on red blood cells.

Research RF Safe Research Library Jan 1, 2017

An in vitro study examined red blood cells exposed to an 18 GHz electromagnetic field and assessed uptake of nanospheres. The authors report that EMF exposure enabled nanosphere uptake into RBCs, with different translocation behavior for 23.5 nm versus 46.3 nm particles. Uptake was reported to increase with higher…

A Route to Chaotic Behavior of Single Neuron Exposed to External Electromagnetic Radiation.

Research RF Safe Research Library Jan 1, 2017

This computational study investigates nonlinear membrane-potential dynamics in a Fitzhugh-Nagumo single-neuron model that includes an external electromagnetic radiation term. The authors report that increasing the frequency of an external transmembrane current leads to mode selection among periodic, quasi-periodic,…

Electromagnetic Fields Act Similarly in Plants as in Animals: Probable Activation of Calcium Channels via Their Voltage Sensor

Research RF Safe Research Library Jan 1, 2016

This narrative review proposes that low-intensity microwave/lower-frequency EMFs activate plasma membrane calcium channels in animals, increasing intracellular calcium and triggering downstream signaling including oxidative stress pathways. It further suggests that EMF actions in terrestrial multicellular plants are…

Fundamental study on a gene transfection methodology for mammalian cells using water-in-oil droplet deformation in a DC electric field.

Research RF Safe Research Library Jan 1, 2016

This paper describes an in vitro gene transfection technique termed water-in-oil droplet electroporation, using an intense DC electric field to deform a droplet between electrodes. The deformation can cause an instantaneous short circuit, during which transient membrane pores are reported to form and permit exogenous…

[Synergistic inhibitory effect of static magnetic field and antitumor drugs on Hepa1-6 cells].

Research RF Safe Research Library Jan 1, 2015

This in vitro study tested whether a static magnetic field (SMF) could enhance the effects of cisplatin or adriamycin in Hepa1-6 tumor cells. The abstract reports that SMF combined with either drug increased growth inhibition and was associated with cell-cycle arrest, increased DNA damage, and more severe membrane…

Electromagnetic fields (UHF) increase voltage sensitivity of membrane ion channels; possible indication of cell phone effect on living cells.

Research RF Safe Research Library Jan 1, 2015

This in vitro study used voltage clamp recordings of single OmpF porin channels in an artificial bilayer to test effects of UHF EMF (910–990 MHz). The authors report frequency-dependent changes in channel gating, with increased gating frequency and voltage sensitivity and a maximum effect at 930 MHz. Conductance was…

Assessment of the neurotoxic potential of exposure to 50Hz extremely low frequency electromagnetic fields (ELF-EMF) in naïve and chemically stressed PC12 cells

Research RF Safe Research Library Jan 1, 2014

This in vitro study tested acute (30 min) and sub-chronic (48 h) 50 Hz ELF-EMF exposure up to 1000 µT in naïve and chemically stressed PC12 cells. Across assays of Ca2+ homeostasis, ROS production, and membrane integrity, the study reports no consistent or measurable neurotoxic effects under the tested conditions.…

[Effect of low-intensity 900 MHz frequency electromagnetic radiation on rat liver and blood serum enzyme activities].

Research RF Safe Research Library Jan 1, 2014

This animal study compared rat liver and blood serum enzyme activities after a total two-hour exposure to low-intensity 900 MHz electromagnetic fields delivered as either a single or fractional schedule. The authors report that creatine kinase (liver and serum) and serum alkaline phosphatase were the most sensitive…

Simulation of colloidal fouling by coupling a dynamically updating velocity profile and electric field interactions with Force Bias Monte Carlo methods for membrane filtration.

Research RF Safe Research Library Jan 1, 2013

This engineering simulation study models colloidal particle transport and deposition in a membrane filtration channel at a particle volume fraction of 10%. The model couples a dynamically updating crossflow velocity field with particle-particle and particle-membrane interaction potentials (electrostatic double layer…

Electric Field Controlled Self-Assembly of Hierarchically Ordered Membranes.

Research RF Safe Research Library Jan 1, 2012

This in vitro study examined how an externally applied electric field influences the self-assembly of oppositely charged molecules in water into an ordered membrane. The authors report that electric fields changed the kinetics of membrane formation and altered membrane thickness, nanofiber growth orientation, and…

Down-regulation of metallothionein 1 and 2 after exposure to electromagnetic field in mouse testis.

Research RF Safe Research Library Jan 1, 2011

This animal study examined mouse testis after 8 weeks of exposure to a 3 MT electromagnetic field (4 hours/day). The authors report significant histological changes (increased primary spermatocytes, increased Leydig cells, and increased basement membrane thickness) in exposed mice versus controls. MT1 and MT2…

Frequency-dependent electrodeformation of giant phospholipid vesicles in AC electric field.

Research RF Safe Research Library Jan 1, 2010

This paper presents a theoretical model of giant phospholipid vesicle deformation in an alternating-current electric field, based on minimizing membrane bending energy and electric-field energy. The model treats the membrane and surrounding aqueous media as leaky dielectrics and reports good quantitative agreement…

Disintegration efficiency of pulsed electric field induced effects on onion (Allium cepa L.) tissues as a function of pulse protocol and determination of cell integrity by ¹H-NMR relaxometry.

Research RF Safe Research Library Jan 1, 2010

This experimental study examined how pulsed electric field (PEF) processing parameters affect cell membrane rupture in onion tissue disks, using ion leakage as the primary integrity measure. Disintegration efficiency increased with field strength up to 500 V/cm and varied with pulse width, pulse number, and…

Critical electric field strengths of onion tissues treated by pulsed electric fields.

Research RF Safe Research Library Jan 1, 2010

This experimental study examined how pulsed electric fields affect onion tissue integrity and texture across different field strengths and pulse counts. It reports distinct critical field strengths for plasma membrane versus tonoplast membrane breakdown, with higher thresholds needed for tonoplast disruption. Effects…

Mitomycin C-associated radiofrequency microelectrocautery used in myringotomy in an animal model.

Research RF Safe Research Library Jan 1, 2009

This experimental animal study compared tympanic membrane closure time after myringotomy performed by microknife versus radiofrequency microcautery, with and without mitomycin C. Radiofrequency myringotomy differed significantly from knife myringotomy, and the 0.7 mm radiofrequency tip combined with mitomycin C was…

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