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Hepatocellular carcinoma therapy finds a channel on the radio

Research RF Safe Research Library Jan 1, 2019

This EBioMedicine commentary discusses tumour-specific amplitude-modulated RF EMF as an anti-cancer therapy for hepatocellular carcinoma and highlights Cav3.2 (CACNA1H) T-type calcium channels as a proposed mediator of the effect. It notes that the reported whole-body averaged SAR in a treated HCC patient was below…

Toxicology and carcinogenesis studies in Sprague Dawley (Hsd:Sprague Dawley SD) rats exposed to whole-body radio frequency radiation at a frequency (900 MHz) and modulations (GSM and CDMA) used by cell phones

Research RF Safe Research Library Jan 1, 2018

This National Toxicology Program technical report describes 900 MHz whole-body RFR exposures (GSM and CDMA) in male and female Sprague Dawley rats from in utero through up to 2 years. The report concludes clear evidence of carcinogenic activity in males for both modulations based on malignant schwannoma of the heart,…

Estimating transmitted power density from mobile phone: an epidemiological pilot study with a software modified phone.

Research RF Safe Research Library Jan 1, 2018

This pilot study evaluated weekly and annual cumulative RF-EMF exposure attributed to mobile phone use using objective phone-based measurements of transmitted and received power densities. Ten participants provided two months of daily data across usage modes (cellular calls, cellular data, and Wi-Fi). The study…

Electromagnetic fields exposure assessment among workers at broadcast centers in Poland.

Research RF Safe Research Library Jan 1, 2018

This exposure assessment study estimated occupational RF electric-field exposure among workers at 4 broadcast centers in Poland using spot measurements and historical occupational hygiene data. Reported maximum and average electric-field values were below the Polish occupational exposure limit for a work shift. The…

Symptom Presentation in Idiopathic Environmental Intolerance With Attribution to Electromagnetic Fields: Evidence for a Nocebo Effect Based on Data Re-Analyzed From Two Previous Provocation Studies.

Research RF Safe Research Library Jan 1, 2018

This paper re-analyzes data from two prior double-blind provocation studies involving RF base station signals and sham exposures. Symptoms and reduced well-being were more strongly associated with participants' belief that the base station was "on" than with the exposure condition itself. The authors conclude that a…

Impact of Long-Term RF-EMF on Oxidative Stress and Neuroinflammation in Aging Brains of C57BL/6 Mice.

Research RF Safe Research Library Jan 1, 2018

This animal study exposed 14-month-old C57BL/6 mice to 1950 MHz RF-EMF (SAR 5 W/kg) for 8 months. The authors report that aging was associated with increased oxidative damage, DNA damage, apoptosis, and glial activation markers in brain tissue. Long-term RF-EMF exposure did not change these markers in aged mice and…

AN EMPIRICAL STUDY: THE IMPACT OF THE NUMBER OF USERS ON ELECTRIC FIELD STRENGTH OF WIRELESS COMMUNICATIONS.

Research RF Safe Research Library Jan 1, 2018

This study used real-time measurements on a university campus to examine how the number of users relates to RF electric field strength from cellular systems and a Wi-Fi access point. The authors report empirical models that estimate E from user counts, with stated accuracies of 86% for cellular-related measurements…

Evaluation of MRI RF electromagnetic field induced heating near leads of cochlear implants.

Research RF Safe Research Library Jan 1, 2018

This simulation study evaluated RF-induced heating near cochlear implant leads during 1.5 T MRI using a transfer function method. Across studied configurations, the average temperature rise was 0.79 °C and the maximum was 2.80 °C at a whole-body average SAR of 2 W/kg. The authors report that lead trajectory and MRI…

Effect of 900-MHz Electromagnetic Field on the Cerebellum: A Histopathological Investigation.

Research RF Safe Research Library Jan 1, 2018

This animal study evaluated histopathological effects of 900-MHz RF-EMF exposure on the rat cerebellum. The exposed group showed intense caspase-3 expression in Purkinje and granular cells and histological changes consistent with apoptosis. Cerebellar layer thickness appeared reduced in exposed animals, although…

Low frequency electromagnetic field decreases ischemia-reperfusion injury of human cardiomyocytes and supports their metabolic function.

Research RF Safe Research Library Jan 1, 2018

This in vitro study tested whether extremely low frequency/low frequency electromagnetic field (LF-EMF) exposure modifies ischemia-reperfusion injury in human cardiac-related cell types. Using LDH and MMP-2 activities and fluorescein diacetate staining, the authors report that short courses of LF-EMF reduced cellular…

Modeled and perceived RF-EMF, noise and air pollution and symptoms in a population cohort. Is perception key in predicting symptoms?

Research RF Safe Research Library Jan 1, 2018

This cohort study compared modeled residential RF-EMF, noise, and air pollution exposures with participants’ perceived exposure levels and self-reported symptoms. Correlations between modeled and perceived exposure were moderate for air pollution and noise but low for RF-EMF. Perceived exposure was consistently…

Spatial electromagnetic field intensity modelling of global system for mobile communication base stations in the Istanbul Technical University Ayazaga campus area.

Research RF Safe Research Library Jan 1, 2018

This study measured RF electric field intensities at 900 and 1800 MHz at 29 points on the Istanbul Technical University campus and produced spatial EMF intensity heat maps using GIS interpolation. Three interpolation methods were compared and the mapped measurements were evaluated against ICNIRP reference limits. All…

Does acute radio-frequency electromagnetic field exposure affect visual event-related potentials in healthy adults?

Research RF Safe Research Library Jan 1, 2018

This double-blind, randomized, counterbalanced study tested whether acute GSM-like 920 MHz RF-EMF exposure affects visual event-related potentials in 36 healthy adults. Compared with sham, exposure was associated with reduced P1 amplitude and increased anterior N1 latency, with no effects on other ERP measures. The…

Comparison of radiofrequency electromagnetic field exposure levels in different everyday microenvironments in an international context.

Research RF Safe Research Library Jan 1, 2018

This exposure assessment quantified RF-EMF levels using portable, high-sampling-rate devices across 94 outdoor microenvironments and 18 public transport vehicles in six countries. Mean outdoor exposure ranged from 0.23 to 1.85 V/m, and public transport exposure ranged from 0.32 to 0.86 V/m. Exposure varied…

Gene Expression Analysis in Human Peripheral Blood Cells after 900 MHz RF-EMF Short-Term Exposure.

Research RF Safe Research Library Jan 1, 2018

This ex vivo/in vitro study exposed peripheral blood cells from five human donors to a 900 MHz continuous-wave RF-EMF for up to 90 minutes (average SAR 9.3 W/kg). After false discovery rate adjustment, the authors report no EMF-specific gene expression changes on microarray analysis. Although low-stringency analysis…

Effects of 1800 MHz RF-EMF exposure on DNA damage and cellular functions in primary cultured neurogenic cells.

Research RF Safe Research Library Jan 1, 2018

This in vitro study exposed primary cultured astrocytes, microglia, and cortical neurons to 1800 MHz RF-EMF at 4.0 W/kg SAR to assess DNA damage and cellular functions. The authors report no significant induction of γH2AX foci and no significant changes in cytokine secretion or dendrite/synapse morphological…

SAR thresholds for electromagnetic exposure using functional thermal dose limits.

Research RF Safe Research Library Jan 1, 2018

This paper analyzes how conservative current localized RF EMF SAR basic restrictions may be by estimating the implied safety factor. The authors derive thermal dose–functional SAR limits from literature-reported thresholds for acute local tissue damage and compare these to existing basic restrictions. They report…

Effects of 1950 MHz radiofrequency electromagnetic fields on Aβ processing in human neuroblastoma and mouse hippocampal neuronal cells.

Research RF Safe Research Library Jan 1, 2018

This in vitro study exposed HT22 mouse hippocampal neuronal cells and SH-SY5Y human neuroblastoma cells to 1950 MHz RF-EMF at SAR 6 W/kg for 2 hours per day over 3 days. RF-EMF exposure reduced mRNA levels of several Aβ-processing genes in HT22 cells, but did not change APP mRNA in SH-SY5Y cells. Protein levels of…

Novel synthesis of MeO (Ni, Cu, La)@Nano-CoO from combination of complexation and impregnation in ultrasonic intervention for low temperature oxidation of toluene under microwave radiation.

Research RF Safe Research Library Jan 1, 2018

This engineering study describes synthesis of nano-metal binary oxide catalysts using complexation and impregnation with ultrasonic intervention for low-temperature catalytic oxidation of toluene under microwave radiation. The La-Co catalyst prepared with ultrasonic intervention is reported to have the best…

From the Cover: 2.45-GHz Microwave Radiation Impairs Hippocampal Learning and Spatial Memory: Involvement of Local Stress Mechanism-Induced Suppression of iGluR/ERK/CREB Signaling.

Research RF Safe Research Library Jan 1, 2018

This mouse study examined low-level 2.45 GHz continuous-wave microwave exposure for 2 hours/day over 15, 30, or 60 days. The authors report impaired learning and spatial memory performance on an 8-arm radial maze after exposure. They also report increased corticosterone and stress/inflammatory-related markers with…

NTP Technical Report on the Toxicology and Carcinogenesis Studies: GSM- and CDMA-modulated Cell Phone RFR, NTP TR 595

Research RF Safe Research Library Jan 1, 2018

This NTP technical report describes long-term rat studies exposing animals to 900 MHz GSM and CDMA-modulated radiofrequency radiation at whole-body SAR levels of 0, 1.5, 3, and 6 W/kg, including exposure beginning before birth. The abstract reports NTP concluded there was "clear evidence" for malignant schwannoma of…

Effect of Exposure to 900 MHz GSM Mobile Phone Radiofrequency Radiation on Estrogen Receptor Methylation Status in Colon Cells of Male Sprague Dawley Rats

Research RF Safe Research Library Mar 1, 2017

This animal study exposed male Sprague-Dawley rats to 900 MHz GSM mobile phone RF radiation for 4 hours and assessed ERα promoter methylation in colon tissue. The authors report altered ERα methylation patterns versus controls after RF exposure. They also report no radioadaptive response in ERα methylation following…

Miniaturized Battery-Free Wireless Systems for Wearable Pulse Oximetry.

Research RF Safe Research Library Jan 1, 2017

This engineering study describes miniaturized, flexible, battery-free wearable pulse oximetry systems that use near-field communication (NFC) for wireless operation. The devices capture and transmit photoplethysmograms to derive blood oxygenation, heart rate, and heart rate variability. The abstract reports…

Effects of radiofrequency radiation in the presence of gold nanoparticles for the treatment of renal cell carcinoma.

Research RF Safe Research Library Jan 1, 2017

This in vitro study evaluated radiofrequency (RF) radiation with and without gold nanoparticles in human embryonic kidney (HEK) cancer cells as a potential approach for renal cell carcinoma treatment. The authors report reduced cell survival in one RF-exposed group versus control, and additional reductions in…

Radiofrequency Pulmonary Vein Isolation in a Patient with Dextrocardia With Situs Inversus Totalis.

Research RF Safe Research Library Jan 1, 2017

This case report describes radiofrequency pulmonary vein isolation in a 67-year-old man with dextrocardia and situs inversus totalis. The procedure successfully isolated all pulmonary veins using 3D mapping with intracardiac echocardiography guidance. No procedural complications were reported, and the authors…

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