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Mitigation of 3.5 GHz Electromagnetic Field-Induced BV2 Microglial Cytotoxicity by Polydeoxyribonucleotide

Research RF Safe Research Library Jan 1, 2025

This in vitro study exposed BV2 mouse microglial cells to 3.5 GHz EMF for 2 hours and reports reduced cell growth and increased apoptosis alongside oxidative stress and signaling changes. The authors report that ROS generation and activation of JNK-1/2 and p38 MAPK were key events in the observed cytotoxicity. Polydeoxyribonucleotide (PDRN) reportedly reduced several EMF-associated cytotoxicity markers, suggesting a potential mitigating effect under the tested conditions.

The influence of Wi-Fi on the mesonephros in the 9-day-old chicken embryo

Research RF Safe Research Library Jan 1, 2025

This animal study examined continual 2.4 GHz Wi‑Fi exposure (200–500 μW/m²) during 9 days of chicken embryo incubation and assessed the mesonephros at day 9. The authors report no adverse effects on general mesonephros development, but describe moderate degenerative changes and vascular congestion without inflammatory infiltrate. They also report significantly increased apoptotic and proliferating cells and up-regulation of caspase‑1 gene expression, interpreted as disruption of regulatory processes during development.

The proliferation rates of HT-1080 human fibrosarcoma cells can be accelerated or inhibited by weak static and extremely low frequency magnetic fields

Research RF Safe Research Library Jan 1, 2025

This in vitro study exposed HT-1080 human fibrosarcoma cells for 4 days to weak extremely low frequency magnetic fields (10 μT, 12–33 Hz) superimposed on a 45 μT static field. The authors report frequency- and amplitude-dependent increases or decreases in cell growth, including sharp inversions near 16.5 Hz with small parameter changes or reversal of the static field direction. Associated changes in membrane potential, intracellular calcium, and mitochondrial superoxide are presented as supporting a bioenergetic mechanism.

Impact of magnetic fields from tablets, laptops, smartphones, and household/leisure magnets on cardiac implantable electronic devices

Research RF Safe Research Library Jan 1, 2025

This study tested magnetic fields from tablets, laptops, smartphones, and household/leisure magnets against 13 cardiac implantable electronic device (CIED) models to assess magnet mode activation. It reports that these consumer devices can trigger magnet mode when in close proximity, with median activation distances of 5–6.5 mm for phones/tablets/laptops and mainly contact-level activation for household/leisure magnets. None of the tested devices activated magnet mode at distances of 20 mm or more, and the authors emphasize patient awareness of proximity-related risk.

SAR Estimations in a Classroom with Wireless Computers

Research RF Safe Research Library Jan 1, 2025

This study simulated 1 g and 10 g peak spatial SAR (psSAR) in classroom settings where each student uses a Wi‑Fi laptop at 2.45 GHz and 100 mW. Maximum simulated psSAR values were reported to be below ICNIRP and IEEE recommended limits, but desk spacing and multi-user configurations could substantially increase psSAR compared with a single-user setup. The authors emphasize that long-term low-level exposure, particularly for children, remains a concern and recommend mitigation via increased spacing and wired connections.

Bus-exposure matrix, a tool to assess bus drivers' exposure to physicochemical hazards

Research RF Safe Research Library Jan 1, 2025

This paper describes the development of a Bus-Exposure Matrix (BEM) to retrospectively estimate Swiss bus drivers’ exposures to 10 physicochemical hazards, including electric and magnetic fields. Measurements in representative buses were combined with technical inventories and INLA modeling to estimate annual exposures from 1985–2022. Reported trends include increasing peak noise and electric-field exposures over time, alongside decreases in several air pollution, vibration, and noise metrics.

Human achromatic flickers and phosphenes thresholds under extremely low frequency electric stimulations

Research RF Safe Research Library Jan 1, 2025

This study estimated thresholds and locus for human phosphene perception during non-invasive transcranial alternating current stimulation at 20, 50, 60, and 100 Hz. Perception depended significantly on stimulation intensity, with the lowest threshold at 20 Hz and no reported phosphenes at 100 Hz. The authors report dosimetry consistent with a retinal origin and frame the findings as relevant for informing cautious ELF exposure limits in safety guidelines.

Influence of geomagnetic disturbances on myocardial infarctions in women and men from Brazil

Research RF Safe Research Library Jan 1, 2025

This ecological analysis used a public health database of myocardial infarction admissions in São José dos Campos, Brazil (1998–2005) and categorized geomagnetic activity using the planetary Kp index. The abstract reports a higher relative frequency of MI admissions during disturbed geomagnetic conditions compared with quiet periods, with a stronger association in women. Unsupervised k-means clustering reportedly supported the sex-specific pattern.

Effects of Polarized Coherent Microwaves Modulated at Extremely Low Frequencies

Research RF Safe Research Library Jan 1, 2025

This review-style text discusses polarized, coherent microwaves that are modulated and pulsed at extremely low frequencies (ELF) and suggests these characteristics may increase biological interactions. It emphasizes that intensity variability and ELF modulation are important for understanding EMF–biology interactions. It also states that such exposures have been linked to health risks in the scientific literature, framing the topic as relevant to EMF safety and public health risk mitigation.

A comprehensive mechanism of biological and health effects of anthropogenic extremely low frequency and wireless communication electromagnetic fields

Research RF Safe Research Library Jan 1, 2025

This narrative review discusses biological mechanisms and reported health effects of anthropogenic extremely low frequency (ELF) and wireless communication (WC) electromagnetic fields. It highlights oxidative stress and DNA damage as key mechanistic endpoints and proposes an IFO-VGIC pathway linking EMF exposure to ROS overproduction and cellular dysfunction. The authors interpret the broader literature as indicating risks (e.g., cancer, infertility, EHS) even below current exposure limits and advocate precautionary policy measures, including stricter limits and a 5G moratorium.

Rapid Deployment of 5G Wireless Communication and Risk Assessment on Human Health: Quid Novi?

Research RF Safe Research Library Jan 1, 2025

This review discusses the rapid deployment of 5G and the associated debate about potential human health impacts from EMF exposure, particularly at 3.5–26 GHz including millimeter waves. It emphasizes limited published studies in these exposure ranges and highlights EU-funded initiatives and research consortia aimed at closing knowledge gaps. The authors state that guidelines are generally considered adequate at present, but argue that uncertainties—especially regarding long-term exposure—support continued research and precautionary approaches.

5G-exposed human skin cells do not respond with altered gene expression and methylation profiles

Research RF Safe Research Library Jan 1, 2025

This in vitro study exposed human skin cells (fibroblasts and keratinocytes) to 5G-band electromagnetic fields for 2 hours and 48 hours using a fully blinded design. Exposures were up to ten times permissible limits, with sham exposure as a negative control and UV exposure as a positive control. The study reports that observed gene expression and DNA methylation differences were minor and consistent with random variation, supporting no detectable EMF-related effect under the tested conditions.

Impact of mobile phone-emitted non-ionizing electromagnetic radiation on parotid gland function: A comprehensive study

Research RF Safe Research Library Jan 1, 2025

This cross-sectional study of 104 university student volunteers assessed whether mobile phone-emitted non-ionizing electromagnetic radiation is associated with changes in parotid gland-related salivary measures. The authors report higher salivary flow rate and pH with longer mobile phone usage duration, along with side-related differences in albumin, IMA, and IMAR. The paper concludes that consistent exposure to mobile phone NIER and associated heat adversely affects parotid gland function and frames this as a health risk, while calling for further long-term research.

Epidemiological criteria for causation applied to human health harms from RF-EMF exposure: Bradford Hill revisited

Research RF Safe Research Library Jan 1, 2025

This paper is a commentary reviewing how Bradford Hill’s epidemiological criteria can be applied to multidisciplinary evidence on RF-EMF exposure and adverse health effects. It reports that systematic reviews and meta-analyses in this area often reach substantially different conclusions, and argues that key weaknesses in primary studies—especially exposure measurement error and insufficient time for long-latency tumors—help explain the divergence. The author suggests these limitations may cause underestimation of potential causation if the associations are truly causal, and calls for independent guidelines to improve future epidemiological research quality.

Skin Fibroblasts from Individuals Self-Diagnosed as Electrosensitive Reveal Two Distinct Subsets with Delayed Nucleoshuttling of the ATM Protein in Common

Research RF Safe Research Library Jan 1, 2025

This study reports on 26 adults self-diagnosed with electromagnetic hypersensitivity (EHS) who provided skin biopsies to generate primary fibroblast lines. The authors describe two EHS subsets based on questionnaire and DNA damage-related measures, and report delayed ATM nucleoshuttling after X-ray exposure in all samples, interpreted as impaired DNA repair signaling. They propose a molecular model linking EHS to ATM pathway dysfunction and suggest this could relate to increased cancer risk or accelerated aging.

Exposure Perception and Symptom Reporting in Idiopathic Environmental Intolerance Attributed to Electromagnetic Fields Using a Co-Designed Provocation Test

Research RF Safe Research Library Jan 1, 2025

This co-designed provocation study in IEI-EMF volunteers evaluated whether perceived exposure and symptom reporting tracked actual EMF exposure under double-blind conditions. The abstract reports no consistent alignment between perceived exposure certainty or symptoms and true exposure status at the group level, with limited individual exceptions. Symptom reporting was related to certainty of being exposed for about half of participants, which the authors interpret as supporting a nocebo-type mechanism and motivating refinement of provocation protocols.

Electrohypersensitivity: what is belief and what is known?

Research RF Safe Research Library Jan 1, 2025

This article addresses electrohypersensitivity (EHS) in the context of public health and EMF-related health concerns. It focuses on distinguishing beliefs about EMF effects from what is currently supported by scientific evidence. The provided text notes ongoing debate and concern and calls for critical assessment of both beliefs and empirical findings.

What is the effect of alarmist media and radiofrequency electromagnetic field (RF-EMF) exposure on salivary cortisol and non-specific symptoms?

Research RF Safe Research Library Jan 1, 2025

This randomized study tested whether viewing alarmist media and participating in an open-label RF-EMF provocation trial influenced non-specific symptoms and salivary cortisol. Participants who believed they were being exposed reported more symptoms than those who believed they were not exposed. The study did not find a replicated effect of alarmist media or open-label RF-EMF exposure on salivary cortisol, suggesting reported symptoms were more related to perception than cortisol-measured stress.

Exploring the impact of environmental factors on male reproductive health through epigenetics

Research RF Safe Research Library Jan 1, 2025

This narrative review discusses how environmental factors may affect male reproductive health through epigenetic mechanisms, including DNA methylation, histone modifications, chromatin remodeling, and non-coding RNA regulation. It reports that electromagnetic radiation, particularly from mobile phones and wireless devices, is linked in the reviewed literature to reduced sperm count and motility, increased oxidative stress, and chromatin damage. The authors conclude there is a substantive connection between EMF exposure and adverse male reproductive outcomes and suggest practical risk-reduction guidance.

Potential Impacts of Radiofrequency Electromagnetic Fields on the Central Nervous System, Brain Neurotransmitter Dynamics and Reproductive System

Research RF Safe Research Library Jan 1, 2025

This review discusses potential impacts of radiofrequency electromagnetic fields from technologies such as Wi‑Fi and mobile phones on the central nervous system, neurotransmitter dynamics, and reproductive health. It describes proposed mechanisms including oxidative stress, thermal effects, altered neurotransmitter activity, ion channel changes, and neuronal apoptosis, while acknowledging conflicting evidence. The authors note that Wi‑Fi RF exposure has not been confirmed to exceed safety guidelines but argue that updated standards and long-term studies are needed, particularly for children/adolescents and in the context of expanding technologies such as 5G.

Assessing RF EMF exposure in multiple microenvironments across ten European countries with a focus on 5G

Research RF Safe Research Library Jan 1, 2025

This exposure assessment measured environmental and auto-induced RF-EMF across more than 800 microenvironments in ten European countries, with a focus on 5G-related bands. Non-user environmental exposure was reported to be below international guideline values and similar to prior European research, while induced traffic substantially increased measured exposure, especially in uplink scenarios. The study also reports systematic differences by setting (cities vs villages) and by national precautionary limit policies.

5G EMF Exposure at 3.6 GHz in Greece Using Data From Frequency-Selective Monitoring Sensors

Research RF Safe Research Library Jan 1, 2025

This exposure-assessment study analyzed two years of continuous frequency-selective monitoring from 13 sensors in the five largest cities in Greece, focusing on the 3.6 GHz 5G band. It reports a gradual increase in 3.6 GHz environmental EMF levels over time and greater variability than legacy cellular bands, with 30-minute averaging reducing observed fluctuations. Despite the upward trend and variability, all measurements were reported to remain well below Greek and ICNIRP reference levels, and the authors emphasize the value of continuous monitoring as 5G deployment expands.

Deduction of Extrapolation Factors in Realistic Scenarios for In-Situ Assessment of 5G Base Stations

Research RF Safe Research Library Jan 1, 2025

This conference paper examines extrapolation factors used for in-situ EMF exposure assessment of 5G base stations in realistic indoor and outdoor scenarios. Using both frequency-selective and code-selective measurement approaches under varying traffic conditions, it reports substantial variability in extrapolated exposure estimates driven largely by antenna radiation patterns. Outdoor environments showed more stable extrapolation than indoor environments, highlighting challenges for reliable exposure assessment when antenna patterns and network configurations are not well characterized.

An approach for annual analysis of EMF exposure in highly sensitive areas of kindergartens and schools

Research RF Safe Research Library Jan 1, 2025

This paper proposes a time-averaging approach for analyzing long-term EMF exposure using time-series data from three sensors in a regulatory monitoring network. Sensors were installed at two kindergartens and one elementary school, and analyses reported daily/weekly patterns, differences between weekdays and weekends, and site-specific annual increases/decreases. The work emphasizes the value of continuous monitoring in sensitive areas, while not directly assessing health outcomes.

Assessment of RF EMF Exposure to Car Driver from Monopole Array Antennas in V2V Communications Considering Thermal Characteristics

Research RF Safe Research Library Jan 1, 2025

This modeling study assessed RF-EMF exposure from a 5.9 GHz V2V monopole array antenna integrated into a car roof shark-fin antenna. Using COMSOL simulations with an adult male body model inside a vehicle, the authors estimated localized and whole-body SAR and associated core temperature rise over a 30 min averaging period. Reported SAR and temperature rise values were below ICNIRP occupational thermal-based restrictions, leading the authors to conclude the exposure does not pose a threat under the studied conditions.

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