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331 postsCarcinogenicity of extremely low-frequency magnetic fields: A systematic review of animal studies
This PRISMA-based systematic review evaluated 54 animal studies on the carcinogenicity of extremely low-frequency (ELF) magnetic fields. The authors report very little evidence that ELF magnetic fields alone are carcinogenic. Findings on co-carcinogenicity (ELF MFs combined with other agents) are inconclusive, and the review notes a clear indication of publication bias.
Effect of short-term extremely low-frequency electromagnetic field on respiratory functions
This animal study tested whether short-term ELF-EMF exposure alters respiratory physiology in rats. Twenty Wistar albino rats were assigned to control or EMF exposure (50 Hz, 0.3 mT for 2 minutes) with respiratory parameters measured before, during, and after exposure. The study reports changes during exposure (lower respiratory rate and higher cycle duration, inspiration time, and tidal volume) but no differences after exposure, and it frames the findings as relevant to EMF safety and potential health risks.
Electromagnetic wireless remote control of mammalian transgene expression
This animal proof-of-concept study describes an engineered nanoparticle–cell interface (EMPOWER) enabling wireless regulation of transgene expression using a 1-kHz magnetic field. Chitosan-coated multiferroic nanoparticles reportedly generate intracellular ROS that activates KEAP1/NRF2 biosensors connected to ROS-responsive promoters. In a mouse model of type 1 diabetes, implanted engineered cells expressing an EMPOWER-controlled insulin system reportedly normalized blood glucose in response to a weak magnetic field.
Effects of radiofrequency electromagnetic field exposure on cancer in laboratory animal studies, a systematic review
This systematic review evaluated RF EMF exposure and cancer outcomes in experimental animals, including chronic cancer bioassays and tumor-promotion designs. Across 52 included studies, the authors report high certainty of evidence for increased malignant heart schwannomas and gliomas in male rats, and moderate certainty for increased risks of several other tumor types. Many other organ systems showed no or minimal evidence of carcinogenic effects, and the authors note challenges in translating animal findings to human risk assessment due to exposure and mechanistic uncertainties.
The association of widely used electromagnetic waves exposure and pregnancy and birth outcomes in Yazd women: a cohort study
This cohort study of 1,666 women in Yazd City examined electromagnetic-wave exposure from commonly used devices during pregnancy and birth outcomes. Longer cell phone call duration during pregnancy was reported to be associated with higher risk of miscarriage, abnormal birth weight, and abnormal newborn height. Increased cordless phone use was also reported to be linked to abnormal birth weight, while other outcomes were assessed but not described as significantly associated in the abstract.
Sleep and Arousal Hubs and Ferromagnetic Ultrafine Particulate Matter and Nanoparticle Motion Under Electromagnetic Fields: Neurodegeneration, Sleep Disorders, Orexinergic Neurons, and Air Pollution in Young Urbanites
This review/overview argues that ultrafine particulate matter and industrial nanoparticles can reach the brain and accumulate in sleep and arousal regulatory regions, including orexinergic neuron hubs. It reports that ferromagnetic particles in these regions show motion responsive to low-intensity electromagnetic fields (30–50 μT) and describes links to sleep disturbances and neurodegenerative disease markers in young urban residents. The authors frame combined air pollution nanoparticle exposure and low-level EMF as a significant threat and call for monitoring and protective strategies.
Understanding Electromagnetic Hypersensitivity (EHS) From Mobile Phone Radiofrequency Radiation (RFR) Exposure: A Mixed-Method Study Protocol
This paper presents a mixed-method study protocol examining electromagnetic hypersensitivity (EHS) in relation to mobile phone radiofrequency radiation exposure among undergraduate students. The quantitative component aims to identify predictors of EHS using a biopsychosocial model, while the qualitative component explores individual experiences through in-depth interviews. The abstract provides study design details and sample size but does not report study results.
Impact of expectancy on fatigue by exposure to the fifth generation of mobile communication signals
This randomized sham-controlled study in 21 healthy participants tested whether routine-level 5G RF-EMF exposure affects fatigue and EEG power, while manipulating expectancy via correct, false, or no information about exposure order. The study reports no change in EEG power with real versus sham exposure. However, self-reported fatigue varied with the conveyed information about being exposed, suggesting an expectancy/psychological priming effect on symptom reporting.
Chicken or egg? Attribution hypothesis and nocebo hypothesis to explain somatization associated to perceived RF-EMF exposure
This longitudinal cohort study examined the temporal relationship between somatization and perceived RF-EMF exposure, comparing the attribution hypothesis with the nocebo hypothesis. Using AMIGO questionnaire data from 2011 and 2015, regression analyses suggested the attribution hypothesis more often explained symptom reporting linked to perceived base station RF-EMF exposure and perceived electricity exposure than the nocebo hypothesis. The authors state this contrasts with prior literature and note that a nocebo effect is not fully excluded.
High Radiofrequency Radiation in the Surroundings of 10 Schools in Örebro, Sweden
This exposure assessment measured outdoor RF radiation from 4G/5G base stations near 10 schools in Örebro, Sweden (October 2024). The authors report maximum levels of 10,716–68,452 μW/m² and state these are far above EUROPAEM EMF guideline ranges; two locations also showed higher peak readings with a second meter. The paper frames these findings as indicating a significant health risk, particularly for children and sensitive groups, though no health outcomes were measured in this study.
The effect on rat peripheral nerve morphology and function of a 900-MHz electromagnetic field applied in the prenatal period
This animal study exposed pregnant Sprague Dawley rats to a 900 MHz electromagnetic field for 1 hour daily throughout gestation and assessed offspring outcomes postnatally. Sciatic nerve analyses at postnatal day 60 indicated persistent morphological alterations attributed to prenatal EMF exposure. However, the reported changes were not severe enough to significantly affect measured functional outcomes (including electrophysiology and locomotor tests).
Effects of 700MHz radiofrequency radiation (5G lower band) on the reproductive parameters of female Wistar rats
This animal study examined short- and long-term 700 MHz (lower-band 5G) radiofrequency exposure in female Wistar rats, comparing control, sham, and exposed groups. It reports no DNA damage and no change in estrous cycle length, but increased ovarian oxidative stress markers in exposed animals. Long-term exposure was associated with ovarian histopathological alterations, while estradiol and progesterone stayed within normal ranges and testosterone increased slightly but significantly.
Possible effects of RF EMR on contextual fear conditioning, hippocampal perivascular space, apoptosis and adrenal gland microarchitecture in rats
This animal study exposed male Wistar rats to 900 MHz RF-EMR from a mobile phone for 1 hour daily over four weeks and assessed behavior and tissue changes. The authors report altered contextual fear conditioning-related behavior in exposed rats. Histological assessments indicated apoptosis and enlarged perivascular space in the hippocampal CA3 region and apoptotic/inflammatory-like changes in the adrenal zona fasciculata, with no reported differences in adrenal medulla cytoarchitecture.
Residential exposure to magnetic field due to high-voltage power lines and childhood leukemia risk in mainland France - GEOCAP case-control study
This French GEOCAP registry-based case-control study evaluated childhood acute leukemia risk in relation to residential proximity to high-voltage overhead power lines and modeled ELF magnetic-field exposure. It reports an increased risk for children under 5 living within 50 m of power lines, particularly when restricting to high-quality geocoded addresses. However, modeled ELF-MF exposure >0.3 µT was not associated with increased risk, and the authors suggest proximity may capture other factors and call for further research and precaution.
Use of Electrical Household Appliances and Risk of All Types of Tumours: A Case-Control Study
This multi-hospital case-control study (n=316) examined associations between use of common household electrical appliances emitting ELF EMF and tumour risk. Most devices showed below-unity odds ratios, while computer screen and microwave oven use showed slightly increased odds with wide confidence intervals. Proximity to electricity transformer stations was associated with higher tumour odds, whereas proximity to powerlines was not.
Effect of electromagnetic field radiation on transcriptomic profile and DNA methylation level in pig conceptuses during the peri-implantation period
This in vitro study exposed pig conceptuses (days 15–16 of pregnancy) to 50 Hz ELF-EMF for 2 hours and assessed transcriptomic and DNA methylation changes. The authors report altered expression of 21 protein-coding transcripts and an approximately 16-fold increase in genomic DNA methylation, with promoter methylation changes in several named genes. They conclude ELF-EMF interacts with gene expression and DNA methylation processes during early development and call for further safety research.
Potential influence of geomagnetic activity on blood pressure statistical fluctuations at mid-magnetic latitudes
This six-year time series analysis used over 500,000 blood pressure measurements from two mid-magnetic latitude cities in China to examine associations with geomagnetic activity (Ap index). The study reports that blood pressure fluctuations correlate with geomagnetic activity and share similar periodic patterns, unlike air temperature and PM2.5. The authors conclude that high geomagnetic activity periods may increase risk for individuals with hypertension and note potential clinical and policy relevance.
The effects of radiofrequency radiation on male reproductive health and potential mechanisms (Review)
This narrative review summarizes human and animal research on radiofrequency (RF) radiation exposure (e.g., mobile phones, Wi‑Fi, occupational sources) and male reproductive outcomes. It reports that the literature links RF exposure with reduced sperm quality and increased DNA damage, often alongside oxidative stress and other proposed biological changes. Although inconsistencies are acknowledged, the authors conclude the overall evidence suggests harmful associations and call for standardized, long-term studies and reconsideration of guidelines.
Use of Mobile and Cordless Phones and the Association with Prostate Cancer
This pooled analysis of two prior human studies reports increased odds of prostate cancer associated with mobile phone use, with higher estimates for longer latency and higher cumulative hours. Cordless phone use is reported to show increased risk but not statistically significant overall, with one mid-range cumulative use category showing an elevated OR. The abstract also reports higher risks among men with more aggressive prostate cancer and among those with a family history of prostate cancer.
Could electrohypersensitivity be a specific form of high sensory processing sensitivity?
This cross-sectional questionnaire study (n=100) examined whether electrohypersensitivity (EHS) overlaps with high sensory processing sensitivity (HSPS). A higher proportion of HSPS was observed among those reporting EHS symptoms, alongside significant differences in anxiety/depression symptomatology and EMF-related risk perception and avoidance strategies. The authors interpret the results as supporting an association between EHS and HSPS, while noting that this does not establish whether EM radiation directly causes EHS symptoms.
Self-diagnosing electromagnetic hypersensitivity-A case study
No abstract was provided in the source text. The provided overview indicates this is a case study of self-diagnosed electromagnetic hypersensitivity (EHS), describing symptoms attributed by an individual to EMF exposure. The supplied text emphasizes ongoing concern about potential health risks and calls for rigorous scientific inquiry and support for affected individuals.
RF-EMF exposure assessment with add-on uplink exposure sensor in different microenvironments in seven European countries
This exposure assessment study introduces a cost-efficient add-on sensor attached to a smartphone to quantify auto-induced uplink RF-EMF transmission across 100–6000 MHz in multiple microenvironments. Activity-based surveys were conducted in seven European countries under non-user, maximum downlink, and maximum uplink scenarios. Reported power levels were lowest for non-user scenarios and higher during active use, with variation by country, urbanization, and setting. The authors frame the work as supporting future epidemiological research and planned validation against other tools.
Repeated Head Exposures to a 5G-3.5 GHz Signal Do Not Alter Behavior but Modify Intracortical Gene Expression in Adult Male Mice
This animal study examined repeated asymmetrical head exposure to a 5G-modulated 3.5 GHz signal in adult male mice for six weeks. It reports no significant changes in locomotion, anxiety, or object-based memory performance under the tested conditions. However, it found statistically significant but limited cortical gene expression changes (<1% of expressed genes), including enrichment for glutamatergic synapse-related genes and lateralized differences involving mitochondrial genome-encoded genes. The authors caution that potential health risks from these intracortical transcriptomic modifications should not be downplayed and note uncertainties about longer exposures and other populations.
5G Radiofrequency Exposure Reduces PRDM16 and C/EBP � mRNA Expression, Two Key Biomarkers for Brown Adipogenesis
This animal study exposed juvenile and young adult Wistar rats to 5G (3.5 GHz) or 2G (900 MHz) radiofrequency fields (1.5 V/m) for 1–2 weeks and measured brown adipose tissue-related gene expression by RT-qPCR. The abstract reports significant downregulation of PRDM16 and C/EBP mRNA after 5G exposure, while UCP1-dependent thermogenesis markers were not significantly changed at the transcriptional level. The authors interpret these findings as a potential partial disruption of brown adipocyte differentiation and raise EMF safety concerns, while calling for further confirmatory research.
The CB1R of mPFC is involved in anxiety-like behavior induced by 0.8/2.65 GHz dual-frequency electromagnetic radiation
This animal study reports that dual-frequency RF EMR exposure (0.8/2.65 GHz, 4 W/kg) induced anxiety-like behavior in mice. It also reports reduced CB1R and endocannabinoid levels in the mPFC and altered endocannabinoid system markers in the BLA. CB1R overexpression or knockdown in the mPFC reportedly decreased or increased anxiety-like behavior, respectively, suggesting a mechanistic link in this model.