Activation of matrix metalloproteinases and FoxO3a in HaCaT keratinocytes by radiofrequency electromagnetic field exposure.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study exposed HaCaT human keratinocytes to 1760 MHz RF-EMF (SAR 4.0 W/kg; 2 h/day for 4 days). The authors report increased intracellular ROS and increased expression/activity of several matrix metalloproteinases, along with increased phosphorylation of FoxO3a and ERK1/2. Cell growth/viability and…
Effect of extremely low frequency electromagnetic field parameters on the proliferation of human breast cancer.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study tested how varying ELF-EMF parameters (frequency, flux density, duration, and continuous vs switching exposure) affect breast cancer and normal breast epithelial cell lines. The authors report that an optimized switching exposure pattern (7.83 ± 0.3 Hz, 1 mT) reduced viability of MDA-MB-231 cells…
Extremely low frequency electromagnetic fields promote cognitive function and hippocampal neurogenesis of rats with cerebral ischemia.
Research
RF Safe Research Library
Jan 1, 2021
This animal study evaluated whether ELF-EMF exposure affects recovery-related outcomes after cerebral ischemia in rats. Rats exposed to 50 Hz, 1 mT ELF-EMF for 2 hours daily over 28 days showed better Morris water maze performance than untreated rats. The study also reports increased hippocampal neurogenesis markers…
Synergistic effect of electromagnetic fields and nanomagnetic particles on osteogenesis through calcium channels and p-ERK signaling.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro and animal study evaluated whether extremely low frequency EMF exposure (1 mT, 45 Hz, 8 h/day) combined with Fe-based nanomagnetic particles enhances osteogenesis. The authors report no detectable cytotoxicity and increased osteogenic markers/proteins with combined NMP + EMF exposure, alongside…
Effect of a Smartphone-Based App on the Quality of Life of Patients With Heart Failure: Randomized Controlled Trial.
Research
RF Safe Research Library
Jan 1, 2020
This randomized controlled trial evaluated whether adding a smartphone-based app to routine care improves quality of life in hospitalized patients with heart failure. Over 3 months, the app group reported significantly better quality-of-life scores than the control group on the Minnesota Living with Heart Failure…
Effect of Exposure to a Radiofrequency Electromagnetic Field on Body Temperature in Anesthetized and Non-Anesthetized Rats.
Research
RF Safe Research Library
Jan 1, 2020
This animal study examined whether anesthesia and body mass modify body temperature responses to 915 MHz RF exposure at 4 W/kg whole-body SAR for 8 hours. Non-anesthetized, free-moving rats showed no significant temperature change during exposure. In contrast, anesthetized rats showed marked temperature increases,…
[Jurisprudence on occupational radiofrequency diseases].
Research
RF Safe Research Library
Jan 1, 2020
This article reviews Italian jurisprudence on alleged occupational tumours linked to RF EMF exposure (notably from wireless phones), with some cases also involving other RF sources or ELF magnetic fields. It contrasts court decisions that recognized occupational causation with others that rejected it, emphasizing how…
[Cell Phones, Radio Frequencies (RF) and Health: IARC classification and epidemiological updates].
Research
RF Safe Research Library
Jan 1, 2020
This narrative review synthesizes evidence up to September 2019 on health risks from radiofrequency exposure emitted by mobile phones, in the context of IARC's 2013 Group 2B classification. The authors report that the literature does not show a clear risk profile and cannot definitively confirm or refute a health…
[The new AIRM guidelines for workers exposed to electromagnetic fields: health surveillance and fit for work judgment].
Research
RF Safe Research Library
Jan 1, 2020
This report discusses elements of new AIRM (Italian Association of Medical Radiation Protection) guidelines for health surveillance of workers exposed to electromagnetic fields. It focuses on identifying which workers should undergo surveillance and what surveillance should include. The approach described emphasizes…
Is the Increasing Incidence of Thyroid Cancer in the Nordic Countries Caused by Use of Mobile Phones?
Research
RF Safe Research Library
Jan 1, 2020
This ecological analysis reports increasing thyroid cancer incidence over time in Sweden (1970–2017) and similarly across Nordic countries using NORDCAN data (1970–2016), with sharper increases in more recent years. The authors report similar increases for smaller (≤4 cm) and larger (>4 cm) tumors and interpret this…
Enhancement in the ATP level and antioxidant capacity of under continuous exposure to extremely low-frequency electromagnetic field for multiple generations.
Research
RF Safe Research Library
Jan 1, 2020
This multi-generation animal study exposed worms continuously to 50 Hz, 3 mT extremely low-frequency electromagnetic fields and assessed outcomes in the 15th generation. The study reports increased body length, higher ATP content and ATP synthase activity, and upregulated ATP-related gene expression in exposed worms.…
EXTREMELY LOW FREQUENCY ELECTROMAGNETIC FIELD EXPOSURE MEASUREMENT IN THE VICINITY OF WIND TURBINES.
Research
RF Safe Research Library
Jan 1, 2020
This exposure assessment measured extremely low frequency magnetic fields near 22 wind turbines in two wind farms in Greece using a Narda NBM-550 with an EHP-50F probe and processing aligned with the 2013/35/EU Directive. Mean magnetic field intensity at the turbine base was reported as low (0.146 µT) and declined to…
Effect of Rehabilitation with Extremely Low Frequency Electromagnetic Field on Molecular Mechanism of Apoptosis in Post-Stroke Patients.
Research
RF Safe Research Library
Jan 1, 2020
This study evaluated whether adding extremely low frequency electromagnetic field (ELF-EMF) exposure to a rehabilitation program affects apoptosis-related gene expression in post-stroke patients. Forty-eight patients (3–4 weeks post-incident) were divided into ELF-EMF and non-ELF-EMF groups, with the ELF-EMF group…
Antimicrobial activity of rosemary leaf extracts and efficacy of ethanol extract against testicular damage caused by 50-Hz electromagnetic field in albino rats.
Research
RF Safe Research Library
Jan 1, 2020
This animal study exposed male albino rats to a 50 Hz electromagnetic field for 2 or 4 hours and assessed reproductive hormones, oxidative stress markers, and testicular histology after 30 days. The abstract reports that EMF exposure reduced serum FSH, testosterone, and LH and catalase activity, while increasing…
Immune response of mollusk Onchidium struma to extremely low-frequency electromagnetic fields (ELF-EMF, 50 Hz) exposure based on immune-related enzyme activity and De novo transcriptome analysis.
Research
RF Safe Research Library
Jan 1, 2020
This animal study exposed the mollusk Onchidium struma to 50 Hz ELF-EMF at 100 μT or 500 μT for up to one week and assessed immune-related cell counts, enzyme activities, and transcriptomic changes. The 100 μT group showed increased total coelomocyte and spherulocyte density versus control and 500 μT, while some cell…
A single-pulsed electromagnetic field enhances collagen synthesis in tendon cells.
Research
RF Safe Research Library
Jan 1, 2020
This in vitro study reports that a single pulsed electromagnetic field (0.2 Hz) increased expression of tenogenic genes and reduced expression of a matrix-degradation/inflammatory gene (Mmp1) in tendon cells. After 5 days of exposure (3 min/day), collagen type I and total collagen synthesis protein levels were…
Structural and functional correlates of smartphone addiction
Research
RF Safe Research Library
Jan 1, 2020
This cross-sectional MRI study compared individuals meeting psychometric criteria for smartphone addiction (n=22) with controls (n=26). It reports lower gray matter volume in several regions (including left anterior insula and parahippocampal cortex) and lower intrinsic activity in the right anterior cingulate cortex…
Effect of Extremely Low Frequency Electromagnetic Fields on Expression of T-bet and GATA-3 Genes and Serum Interferon-γ and Interleukin-4.
Research
RF Safe Research Library
Jan 1, 2019
This rat study examined 50 Hz ELF-EMF exposure (1–2000 μT) for 60 days and measured Th-related gene expression and cytokines in an HSA-stimulated immune model. Splenic T-bet and GATA-3 mRNA expression decreased at 1 and 100 μT. Serum IFN-γ and IL-4 were significantly decreased in the 100 μT group only before HSA…
The combinatory effect of sinusoidal electromagnetic field and VEGF promotes osteogenesis and angiogenesis of mesenchymal stem cell-laden PCL/HA implants in a rat subcritical cranial defect.
Research
RF Safe Research Library
Jan 1, 2019
This animal and in vitro study evaluated sinusoidal electromagnetic field (SEMF) exposure combined with VEGF in rat mesenchymal stem cells and in a rat cranial defect model using rBMSC-laden PCL/HA scaffolds. The authors report increased osteogenic and endothelial marker expression with SEMF and VEGF, with a slight…
Evaluation of the effects of extremely low frequency electromagnetic field on the levels of some inflammatory cytokines in post-stroke patients.
Research
RF Safe Research Library
Jan 1, 2019
This study evaluated whether adding therapeutic extremely low frequency electromagnetic field (ELF-EMF) treatment to a rehabilitation program affects inflammatory cytokine activity in post-stroke patients. Following ELF-EMF treatment, IL-1β plasma levels and IL-1β mRNA expression increased, and IL-2 plasma levels…
T-Cell Differentiation to T Helper 9 Phenotype is Elevated by Extremely Low-Frequency Electromagnetic Fields Via Induction of IL-2 Signaling.
Research
RF Safe Research Library
Jan 1, 2019
This in vitro study examined 60 Hz extremely low-frequency EMF exposure (0.8 mT) on CD4 T cells under Th9-polarizing conditions. The authors report increased Th9-associated responses including IL-9 secretion, transcription factor changes (including early GATA3), and increased STAT5/STAT6 phosphorylation alongside…
Evaluation of the Validity of a Nonlinear J-Shaped Dose-Response Relationship in Cancers Induced by Exposure to Radiofrequency Electromagnetic Fields.
Research
RF Safe Research Library
Jan 1, 2019
This review discusses the controversial evidence on mobile phone RF-EMF exposure and brain cancer. The authors argue that exposure magnitude may be a key factor contributing to inconsistent findings. They discuss evidence supporting a nonlinear J-shaped dose-response relationship for RF-EMF-related carcinogenesis.
Low-frequency electromagnetic fields as an alternative to sanitize water of drinking systems in poultry production?
Research
RF Safe Research Library
Jan 1, 2019
This study tested pulsed low-frequency electromagnetic fields (up to 10,000 Hz; max 21 mT) as a potential alternative sanitation approach for poultry drinking water systems. LF-EMF exposure was linked to variable changes in culturable bacterial counts, with direction depending on system type and some early…
[The reaction of the circulatory system to stress and electromagnetic fields emitted by mobile phones - 24-h monitoring of ECG and blood pressure].
Research
RF Safe Research Library
Jan 1, 2019
In a worker sample undergoing 24-hour ECG and ambulatory blood pressure monitoring, higher self-reported daily mobile phone use (>60 minutes) was associated with higher systolic blood pressure in office measurement and at night. Higher occupational stress was associated with higher systolic and diastolic blood…