Changes in miR-21, -138, -141, -135 expression and apoptosis/necrosis levels in HCT116 colon cancer cells under 50 Hz ELF-EMF exposure at 0.4 and 0.8 mT
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RF Safe Research Library
Feb 23, 2026
This in vitro study exposed HCT116 colorectal carcinoma cells to 50 Hz ELF-EMF at 0.4 or 0.8 mT for 9 or 18 hours under continuous or discontinuous conditions. The authors report significant changes in miR-21, miR-141, miR-135, and miR-138 expression and increased apoptosis and necrosis measured by flow cytometry.…
Inhibition of mitochondrial NADH:ubiquinone oxidoreductase by spinning oscillating magnetic fields causes toxicity in cancer cells
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RF Safe Research Library
Jan 1, 2026
This in vitro study examines a spinning oscillating magnetic field (sOMF) generated by an Oncomagnetic device and reports selective toxicity in glioma cancer cells. The abstract attributes effects to ROS-dependent inhibition of mitochondrial complex I, with downstream oxidative stress, DNA damage, cell-cycle arrest,…
The Frequency of a Magnetic Field Determines the Behavior of Tumor and Non-Tumor Nerve Cell Models
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RF Safe Research Library
Jan 1, 2025
This in vitro study exposed glioblastoma (CT2A), neuroblastoma (N2A), and non-tumor astrocyte (C8D1A) cell models to a 100 μT magnetic field across 20–100 Hz for 24–72 hours. The abstract reports decreased viability and proliferation in the tumor cell models within a frequency window centered at 50 Hz, while…
Investigating the expression changes of several key genes in prostate cancer cells under exposure to the ELF pulsed electromagnetic fields.
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RF Safe Research Library
Jan 1, 2025
This in vitro study exposed DU-145 prostate cancer cells to extremely low-frequency pulsed electromagnetic fields (ELF P-EMF) at different intensities and times. The authors report increased cell mortality and apoptosis with higher intensity (22.6–35 mT) and longer exposure. They also report gene-expression changes…
Extremely low-frequency electromagnetic field (ELF-EMF) induced alterations in gene expression and cytokine secretion in clear cell renal carcinoma cells.
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RF Safe Research Library
Jan 1, 2024
This in vitro study exposed three ccRCC cell lines and a healthy kidney cell line (HEK293) to 50 Hz ELF-EMF at 4.5 mT for 30 minutes daily over 5 days. The authors report exposure-associated changes in expression of several genes (names not fully visible in the abstract), with differences between primary…
Human osteosarcoma cells in response to ELF-MF: Morphological remodeling compared to cell proliferation.
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RF Safe Research Library
Jan 1, 2023
This in vitro study exposed human osteosarcoma (MG-63) cells to 2 mT extremely low-frequency magnetic fields with sinusoidal, triangular, or pulsed waveforms under continuous (3 h) or fractionated (3 days) conditions. The authors report significant decreases in proliferation and shape index in exposed cells versus…
Effects of prolonged exposure to ELF-EMF on HERVs expression in human melanoma cells.
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RF Safe Research Library
Jan 1, 2022
This in vitro study examined whether 96-hour exposure to 50 Hz ELF-EMF affects expression of human endogenous retroviruses (HERV-H, HERV-K, HERV-W) in SK-MEL-37 human melanoma cells. Cells were continuously exposed at 1.5 or 3 mT and HERV env mRNA levels were measured by qPCR. The authors report significant…
Morphological and cytophysiological changes in selected lines of normal and cancer human cells under the influence of a radio-frequency electromagnetic field.
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RF Safe Research Library
Jan 1, 2021
This in vitro study exposed human fibroblasts and prostate cancer cells to 2.5 GHz RF-EMF for 24, 48, and 72 hours and assessed viability and morphology. The authors report decreased viability in fibroblasts and increased viability in prostate cancer cells after exposure, while morphology showed no significant…
EVALUATION OF BCL2 AND ITS REGULATORY MIRS, MIR-15-B AND MIR-16 EXPRESSION CHANGES UNDER THE EXPOSURE OF EXTREMELY LOW-FREQUENCY ELECTROMAGNETIC FIELDS ON HUMAN GASTRIC CANCER CELL LINE.
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RF Safe Research Library
Jan 1, 2021
This in vitro study examined whether extremely low-frequency electromagnetic fields (ELF-EMF) at 0.2 or 2 mT (continuous or 1.5 h on/1.5 h off) for 18 hours alter viability and gene/miRNA expression in AGS gastric cancer cells. The authors report a significant reduction in cell viability at 2 mT continuous exposure.…
Electromagnetic Field Could Protect SH-SY5Y Cells Against Cisplatin Cytotoxicity, But Not MCF-7 Cells.
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Jan 1, 2018
This in vitro study exposed MCF-7 and SH-SY5Y cells to a 50 Hz, 0.50 mT electromagnetic field in combination with cisplatin and/or morphine. The combined "CDDP+Mor+EMF" condition showed higher cisplatin IC values than cisplatin alone and "CDDP+Mor" in both cell lines, consistent with reduced cisplatin cytotoxicity.…
Effects of extremely low frequency electromagnetic fields on in-vitro cellular cultures HeLa and CHO.
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RF Safe Research Library
Jan 1, 2016
This in-vitro study examined whether 50 Hz extremely low frequency electromagnetic fields affect proliferation in HeLa and CHO cell cultures. The abstract reports increased proliferation in exposed cells versus controls, with the largest reported increase under repetitive exposure at 2.49 mT (40 minutes every 12…
Effect of ELF-EMF Exposure on Human Neuroblastoma Cell Line: a Proteomics Analysis
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RF Safe Research Library
Jan 1, 2014
This in vitro study exposed SH-SY5Y human neuroblastoma cells to a 2 mT, 50 Hz magnetic field for 3 hours and assessed protein expression using proteomics. The authors report that 189 proteins changed expression in exposed cells compared with controls, with PCA/clustering separating samples by condition. They…
P-selectin expression in a colon tumor model exposed by sinusoidal electromagnetic fields.
Research
RF Safe Research Library
Jan 1, 2013
This animal study evaluated whether sinusoidal magnetic field exposure alters P-selectin expression in a rat colon tumor model. Rats exposed to 50 Hz, 5 mT for 6 h/day for 8 months showed no statistically significant change in P-selectin expression by immunohistochemistry. The authors indicate that further in vitro…
Raman spectral analysis of nasopharyngeal carcinoma cell line CNE2 after microwave radiation.
Research
RF Safe Research Library
Jan 1, 2013
This in vitro study used Raman spectroscopy to assess microwave radiation effects on the CNE2 nasopharyngeal carcinoma cell line across exposure times from 2 to 25 minutes. The authors report detectable spectral changes (including C-H deformation and amide I) and significant PCA differences after 10 minutes of…