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    <title>Reviewed Papers — 2000</title>
    <link>https://rfsafe.org/mel/papers_class.php?year=2000</link>
    <description>Reviewed papers published in 2000.</description>
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    <item>
      <title>Low-level exposure to pulsed 900 MHz microwave radiation does not cause deficits in the performance of a spatial learning task in mice.</title>
      <link>https://rfsafe.org/mel/paper.php?id=6373</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6373</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:no_effect</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> No effect &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>Bioelectromagnetics · 2000 · PubMed</small></p>
<p>Adult male C57BL/6J mice exposed to a low-intensity 900 MHz RF field pulsed at 217 Hz (average whole-body SAR 0.05 W/kg) for 45 min/day for 10 days showed no significant field-dependent effects on radial maze choice accuracy or total completion time compared with sham-exposed controls, whether tested immediately after exposure or after 15 or 30 minutes.</p>
<p><small>DOI: 10.1002/(sici)1521-186x(200004)21:3&lt;151::aid-bem1&gt;3.0.co;2-q · PMID: 10723014</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/10723014/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/10723014/</a></small></p>]]></description>
    </item>
    <item>
      <title>[Changes in serum alkaline phosphatase activity during in vitro exposure to amplitude-modulated electromagnetic field of ultrahigh frequency (2375 MHz) in guinea pigs].</title>
      <link>https://rfsafe.org/mel/paper.php?id=6372</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6372</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:harm</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> Harm &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>Biofizika · 2000 · PubMed</small></p>
<p>In vitro exposure to pulse-modulated microwave radiation (carrier 2375 MHz; modulation pulse rate 10–390 Hz) altered alkaline phosphatase activity depending on modulation frequency and intensity. At 70 Hz modulation, alkaline phosphatase activity increased by about 1.8–2.0 times.</p>
<p><small>PMID: 10732222</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/10732222/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/10732222/</a></small></p>]]></description>
    </item>
    <item>
      <title>Differential damage in bacterial cells by microwave radiation on the basis of cell wall structure.</title>
      <link>https://rfsafe.org/mel/paper.php?id=6371</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6371</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:mixed</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:in_vitro</category>
      <description><![CDATA[<p><strong>Effect:</strong> Mixed &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> in_vitro</p>
<p><small>Applied and environmental microbiology · 2000 · PubMed</small></p>
<p>Microwave radiation of Escherichia coli and Bacillus subtilis suspensions was associated with a dramatic reduction in viable counts and increased DNA and protein release as final suspension temperature increased, while cell density did not significantly decrease. Scanning electron microscopy showed severe surface damage in most E. coli cells but no significant change in B. subtilis; microwave-injured E. coli were easily lysed with SDS whereas B. subtilis were resistant.</p>
<p><small>DOI: 10.1128/aem.66.5.2243-2247.2000 · PMID: 10788410</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/10788410/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/10788410/</a></small></p>]]></description>
    </item>
    <item>
      <title>Cancer in radar technicians exposed to radiofrequency/microwave radiation: sentinel episodes.</title>
      <link>https://rfsafe.org/mel/paper.php?id=6370</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6370</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:harm</category>
      <category>evidence:very_low</category>
      <category>year:2000</category>
      <category>study_type:other</category>
      <description><![CDATA[<p><strong>Effect:</strong> Harm &nbsp; <strong>Evidence:</strong> Very low</p>
<p><strong>Study type:</strong> other</p>
<p><small>International journal of occupational and environmental health · 2000 · PubMed</small></p>
<p>The authors describe clusters of multiple tumor types among radar technicians reported to have prolonged high-level RF/microwave exposures, including a cohort of 25 workers with six tumors. They report estimated relative risks for cancer in this group and describe very short latency periods in index patients and a larger self-reported group, concluding that high-level long-duration exposures in settings with lax preventive measures were associated with increased cancer risk and suggesting prevention of exposures in the range of 10–100 microw/cm(2).</p>
<p><small>DOI: 10.1179/oeh.2000.6.3.187 · PMID: 10926722</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/10926722/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/10926722/</a></small></p>]]></description>
    </item>
    <item>
      <title>Biological effects of electromagnetic fields--mechanisms for the effects of pulsed microwave radiation on protein conformation.</title>
      <link>https://rfsafe.org/mel/paper.php?id=6369</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6369</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:unclear</category>
      <category>evidence:very_low</category>
      <category>year:2000</category>
      <category>study_type:other</category>
      <description><![CDATA[<p><strong>Effect:</strong> Unclear &nbsp; <strong>Evidence:</strong> Very low</p>
<p><strong>Study type:</strong> other</p>
<p><small>Journal of theoretical biology · 2000 · PubMed</small></p>
<p>The authors propose a theoretical model in which pulsed microwave radiation can alter protein conformation by transiently heating the protein and its immediate environment, potentially triggering a heat shock/stress response even when no bulk temperature rise is detected by conventional thermometry. Using heat diffusion equation modeling, they report that pulsed athermal exposure could produce transient temperature excursions outside the normal range and suggest this may relate to the power window phenomenon via incomplete heat shock response triggering.</p>
<p><small>DOI: 10.1006/jtbi.2000.2123 · PMID: 10966765</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/10966765/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/10966765/</a></small></p>]]></description>
    </item>
    <item>
      <title>Effect of high-power microwave radiation with nanosecond pulse duration on some biological objects.</title>
      <link>https://rfsafe.org/mel/paper.php?id=6368</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6368</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:unknown</category>
      <category>evidence:unknown</category>
      <category>year:2000</category>
      <description><![CDATA[<p><strong>Effect:</strong> Unknown &nbsp; <strong>Evidence:</strong> Unknown</p>
<p><small>Doklady biophysics : proceedings of the Academy of Sciences of the USSR, Biophysics section · 2000 · PubMed</small></p>
<p><small>PMID: 11029032</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11029032/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11029032/</a></small></p>]]></description>
    </item>
    <item>
      <title>The effect of microwave radiation on the magnetic properties of minerals.</title>
      <link>https://rfsafe.org/mel/paper.php?id=6367</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6367</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:unclear</category>
      <category>evidence:insufficient</category>
      <category>year:2000</category>
      <category>study_type:other</category>
      <description><![CDATA[<p><strong>Effect:</strong> Unclear &nbsp; <strong>Evidence:</strong> Insufficient</p>
<p><strong>Study type:</strong> other</p>
<p><small>The Journal of microwave power and electromagnetic energy : a publication of the International Microwave Power Institute · 2000 · PubMed</small></p>
<p>The paper discusses effects of microwave radiation on common ore minerals, presenting heating rates at varying microwave power levels and comparative magnetic susceptibility surveys for treated versus non-treated minerals. Chemical and physical analyses are considered to quantify changes in mineral phases during heating, with conclusions about potential impacts on downstream magnetic processing.</p>
<p><small>DOI: 10.1080/08327823.2000.11688431 · PMID: 11098439</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11098439/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11098439/</a></small></p>]]></description>
    </item>
    <item>
      <title>Induction of micronuclei in human lymphocytes exposed in vitro to microwave radiation.</title>
      <link>https://rfsafe.org/mel/paper.php?id=6366</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6366</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:harm</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:in_vitro</category>
      <description><![CDATA[<p><strong>Effect:</strong> Harm &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> in_vitro</p>
<p><small>Mutation research · 2000 · PubMed</small></p>
<p>For both radiation frequencies (2.45 and 7.7 GHz), micronuclei were induced compared with control cultures at a power density of 30 mW/cm^2 after 30 and 60 min exposures.</p>
<p><small>DOI: 10.1016/s1383-5718(00)00112-1 · PMID: 11113697</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11113697/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11113697/</a></small></p>]]></description>
    </item>
    <item>
      <title>Effects of microwave radiation and strychnine on cerebral biopotentials in narcotized rats.</title>
      <link>https://rfsafe.org/mel/paper.php?id=6365</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6365</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:harm</category>
      <category>evidence:very_low</category>
      <category>year:2000</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> Harm &nbsp; <strong>Evidence:</strong> Very low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>Bulletin of experimental biology and medicine · 2000 · PubMed</small></p>
<p>Microwave radiation and strychnine produced changes in electrocorticogram spectral parameters and nonlinear dynamics measures (correlation dimension, Kolmogorov entropy) that were opposite to those induced by urethane. The modulatory effect of microwaves on cerebral bioelectric activity in narcotized rats was described as similar to strychnine and probably related to enhanced excitability and increased complexity of bioelectric processes.</p>
<p><small>DOI: 10.1007/bf02682245 · PMID: 11177257</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11177257/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11177257/</a></small></p>]]></description>
    </item>
    <item>
      <title>Inhibitory action of microwave radiation on gamma-glutamyl transpeptidase activity in liver of rats treated with hydrocortisone.</title>
      <link>https://rfsafe.org/mel/paper.php?id=6364</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6364</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:mixed</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> Mixed &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>Folia histochemica et cytobiologica · 2000 · PubMed</small></p>
<p>In rats treated with hydrocortisone, microwave irradiation at 53.57 GHz (power density 10 mW/cm2 and 1 mW/cm2) was reported to block the inducible effect of hydrocortisone on liver GGT activity. The effect was described as dependent on the power density of millimetre microwaves.</p>
<p><small>PMID: 11185725</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11185725/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11185725/</a></small></p>]]></description>
    </item>
    <item>
      <title>Complex permittivities of cyclomaltooligosaccharides (cyclodextrins) over microwave frequencies to 26 GHz.</title>
      <link>https://rfsafe.org/mel/paper.php?id=6363</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6363</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:unclear</category>
      <category>evidence:insufficient</category>
      <category>year:2000</category>
      <category>study_type:engineering</category>
      <description><![CDATA[<p><strong>Effect:</strong> Unclear &nbsp; <strong>Evidence:</strong> Insufficient</p>
<p><strong>Study type:</strong> engineering</p>
<p><small>Carbohydrate research · 2000 · PubMed</small></p>
<p>Complex permittivities for microwave frequencies 0.5–26 GHz were measured for solid-state alpha-, beta-, and gamma-cyclodextrins at room temperature. The real component showed maxima near 0.6 GHz with beta &gt; alpha &gt; gamma across the spectrum. Dielectric loss was significant only between 5 and 12 GHz for beta- and gamma-cyclodextrins, with maxima near 7.5 GHz.</p>
<p><small>DOI: 10.1016/s0008-6215(00)00085-9 · PMID: 10945672</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/10945672/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/10945672/</a></small></p>]]></description>
    </item>
    <item>
      <title>[The study of the microwave reaction of stearic acid and pentyl amine].</title>
      <link>https://rfsafe.org/mel/paper.php?id=6362</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6362</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:benefit</category>
      <category>evidence:insufficient</category>
      <category>year:2000</category>
      <category>study_type:in_vitro</category>
      <description><![CDATA[<p><strong>Effect:</strong> Benefit &nbsp; <strong>Evidence:</strong> Insufficient</p>
<p><strong>Study type:</strong> in_vitro</p>
<p><small>Guang pu xue yu guang pu fen xi = Guang pu · 2000 · PubMed</small></p>
<p>FTIR results indicated that mixing stearic acid and pentyl amine produced pentyl ammonium stearate, forming an acid-salt structure with remaining stearic acid. Under microwave radiation, pentyl ammonium stearate could be decomposed and dehydrated to form stearic pentyl amide, and microwave radiation was suggested to make the reaction faster and more thorough.</p>
<p><small>PMID: 12945403</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/12945403/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/12945403/</a></small></p>]]></description>
    </item>
    <item>
      <title>Ets1 oncogene induction by ELF-modulated 50 MHz radiofrequency electromagnetic field.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5357</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5357</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:mixed</category>
      <category>evidence:very_low</category>
      <category>year:2000</category>
      <category>study_type:in_vitro</category>
      <description><![CDATA[<p><strong>Effect:</strong> Mixed &nbsp; <strong>Evidence:</strong> Very low</p>
<p><strong>Study type:</strong> in_vitro</p>
<p><small>Bioelectromagnetics · 2000 · PubMed</small></p>
<p>After exposure to 50 MHz RF non-ionizing radiation modulated (80%) at 16 Hz, ets1 mRNA was overexpressed in Jurkat T-lymphoblastoid and Leydig TM3 cell lines. The effect was reported only when the 16 Hz modulation was present; the authors also report identifying a putative candidate gene repressed after EMF exposure.</p>
<p><small>DOI: 10.1002/(sici)1521-186x(200001)21:1&lt;8::aid-bem3&gt;3.0.co;2-g · PMID: 10615087</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/10615087/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/10615087/</a></small></p>]]></description>
    </item>
    <item>
      <title>Electromagnetic fields enhance the stress response at elevated temperatures in the nematode Caenorhabditis elegans.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5356</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5356</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:mixed</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> Mixed &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>Bioelectromagnetics · 2000 · PubMed</small></p>
<p>In an experimental setup allowing exposure to 50 Hz magnetic fields (0–150 microT) with precise temperature control, ELF-EMF strongly enhanced heat-shock–related reporter gene expression under defined conditions when combined with mild heat shock.</p>
<p><small>DOI: 10.1002/(sici)1521-186x(200002)21:2&lt;100::aid-bem4&gt;3.0.co;2-u · PMID: 10653620</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/10653620/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/10653620/</a></small></p>]]></description>
    </item>
    <item>
      <title>Morphologic responses of osteoblast-like cells in monolayer culture to ELF electromagnetic fields.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5355</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5355</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:mixed</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:in_vitro</category>
      <description><![CDATA[<p><strong>Effect:</strong> Mixed &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> in_vitro</p>
<p><small>Bioelectromagnetics · 2000 · PubMed</small></p>
<p>Cells exposed for 24 h to a 60 Hz, 0.7 mT rms magnetic field (inducing ~0.5 mV/m rms electric field) were consistently smaller than sham-treated cells, but overall morphologic alterations were not significantly different when cell orientation was not considered. When analyzed by orientation, cells oriented parallel to the induced electric field showed a significant decrease in cell length and an increase in roundness.</p>
<p><small>DOI: 10.1002/(sici)1521-186x(200002)21:2&lt;129::aid-bem8&gt;3.0.co;2-q · PMID: 10653624</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/10653624/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/10653624/</a></small></p>]]></description>
    </item>
    <item>
      <title>Effects of electromagnetic fields on the reproductive success of American kestrels.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5354</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5354</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:mixed</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> Mixed &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>Physiological and biochemical zoology : PBZ · 2000 · PubMed</small></p>
<p>EMF exposure equivalent to that experienced by wild kestrels was weakly associated with reduced egg laying in 1 year only. Across both years, fertility was higher but hatching success was lower in EMF pairs than controls; fledging success was higher in EMF pairs in 1995 only. EMF eggs were larger with more yolk/albumen/water but thinner shells; late-term embryos were larger/longer, while hatchlings were similar in mass and size.</p>
<p><small>DOI: 10.1086/316726 · PMID: 10685907</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/10685907/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/10685907/</a></small></p>]]></description>
    </item>
    <item>
      <title>Variability in EMF permittivity values: implications for SAR calculations.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5353</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5353</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:unclear</category>
      <category>evidence:insufficient</category>
      <category>year:2000</category>
      <category>study_type:engineering</category>
      <description><![CDATA[<p><strong>Effect:</strong> Unclear &nbsp; <strong>Evidence:</strong> Insufficient</p>
<p><strong>Study type:</strong> engineering</p>
<p><small>IEEE transactions on bio-medical engineering · 2000 · PubMed</small></p>
<p>The study analyzed variability in published tissue permittivity data and evaluated how proportional changes in permittivity affect SAR calculations for RF exposures from 1 MHz to 1 GHz using a 4-cm sphere model. When the sphere dimensions are small relative to wavelength, whole-sphere averaged SAR was inversely proportional to permittivity, while localized SAR did not follow the same relationship and varied substantially by location within the sphere.</p>
<p><small>DOI: 10.1109/10.827308 · PMID: 10743782</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/10743782/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/10743782/</a></small></p>]]></description>
    </item>
    <item>
      <title>A meta-analysis of epidemiological studies on the relationship between occupational electromagnetic field exposure and the risk of adult leukemia.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5352</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5352</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:unclear</category>
      <category>evidence:insufficient</category>
      <category>year:2000</category>
      <category>study_type:meta_analysis</category>
      <description><![CDATA[<p><strong>Effect:</strong> Unclear &nbsp; <strong>Evidence:</strong> Insufficient</p>
<p><strong>Study type:</strong> meta_analysis</p>
<p><small>Environmental health and preventive medicine · 2000 · PubMed</small></p>
<p>Meta-analysis of epidemiological studies found combined relative risks above 1.0 for all leukemia (RR=1.11) and for acute lymphocytic (RR=1.38), acute myeloid (RR=1.07), and chronic lymphocytic leukemia (RR=1.14), but these increases were not statistically significant. The authors state it is difficult to make a consistent conclusion and call for better-designed studies with more valid exposure assessment.</p>
<p><small>DOI: 10.1007/bf02935915 · PMID: 21432210</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/21432210/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/21432210/</a></small></p>]]></description>
    </item>
    <item>
      <title>Evaluation of in vitro effects of 50 and 60 Hz magnetic fields in regional EMF exposure facilities.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5350</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5350</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:no_effect</category>
      <category>evidence:moderate</category>
      <category>year:2000</category>
      <category>study_type:in_vitro</category>
      <description><![CDATA[<p><strong>Effect:</strong> No effect &nbsp; <strong>Evidence:</strong> Moderate</p>
<p><strong>Study type:</strong> in_vitro</p>
<p><small>Radiation research · 2000 · PubMed</small></p>
<p>Regional EMF exposure facilities conducted blinded, sham-controlled replication studies of previously reported in vitro effects of 50/60 Hz magnetic-field exposure. In nearly all experiments, no effects of magnetic-field exposure were found on the assessed endpoints.</p>
<p><small>DOI: 10.1667/0033-7587(2000)153[0648:eoiveo]2.0.co;2 · PMID: 10790288</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/10790288/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/10790288/</a></small></p>]]></description>
    </item>
    <item>
      <title>Zeeman-Stark modeling of the RF EMF interaction with ligand binding.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5349</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5349</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:unclear</category>
      <category>evidence:insufficient</category>
      <category>year:2000</category>
      <category>study_type:other</category>
      <description><![CDATA[<p><strong>Effect:</strong> Unclear &nbsp; <strong>Evidence:</strong> Insufficient</p>
<p><strong>Study type:</strong> other</p>
<p><small>Bioelectromagnetics · 2000 · PubMed</small></p>
<p>A quantum Zeeman-Stark model is presented for RF electromagnetic exposure effects on ligand binding, incorporating collision-related energy losses, endogenous nonlinear forces in the binding site, out-of-equilibrium metabolism-related conditions, and thermal noise. The model suggests that in some instances low-intensity exogenous RF exposure could affect ligand binding probability, e.g., when a receptor potential well depth matches RF photon energy.</p>
<p><small>DOI: 10.1002/(sici)1521-186x(200005)21:4&lt;312::aid-bem7&gt;3.0.co;2-# · PMID: 10797459</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/10797459/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/10797459/</a></small></p>]]></description>
    </item>
    <item>
      <title>Experiments showing that electromagnetic fields can be used to treat inflammatory diseases.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5348</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5348</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:benefit</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> Benefit &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>Biomedical sciences instrumentation · 2000 · PubMed</small></p>
<p>0.1 mT, 60 Hz EMFs induced a 20% mean increase in anti-CD3 binding to T cell receptors in Jurkat cells. 60 Hz sinusoidal EMFs and a commercial bone-healing EMF modulated signal transduction pathways regulating lymphocyte proliferation, with similar effects reported in human PBLs in culture and in rat PBLs when donor animals were exposed to a bone-healing field (21 days, 4 hr/day).</p>
<p><small>PMID: 10834201</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/10834201/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/10834201/</a></small></p>]]></description>
    </item>
    <item>
      <title>Effects of 60 Hz extremely low frequency magnetic fields (EMF) on radiation- and chemical-induced mutagenesis in mammalian cells.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5347</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5347</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:no_effect</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:in_vitro</category>
      <description><![CDATA[<p><strong>Effect:</strong> No effect &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> in_vitro</p>
<p><small>Carcinogenesis · 2000 · PubMed</small></p>
<p>A(L) cells exposed to a 100 microT, 60 Hz alternating magnetic field for up to 7 days showed no cytotoxicity and no increase in mutagenesis. Concurrent EMF exposure did not increase cytotoxicity or CD59- mutant induction from graded doses of gamma-radiation or MNNG.</p>
<p><small>PMID: 10837013</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/10837013/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/10837013/</a></small></p>]]></description>
    </item>
    <item>
      <title>Behavior of free-ranging and captive American kestrels under electromagnetic fields.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5346</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5346</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:mixed</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:other</category>
      <description><![CDATA[<p><strong>Effect:</strong> Mixed &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> other</p>
<p><small>Journal of toxicology and environmental health. Part A · 2000 · PubMed</small></p>
<p>Wild reproducing kestrels were estimated to be exposed to EMFs for a substantial portion of time (25%–75% of observed time; 71%–90% on a 24-h basis depending on breeding stage). Captive females exposed to EMFs showed increased activity/alertness and more frequent perching on the pen roof during courtship, and preened/rested less during brood rearing; exposed males were more active during courtship and more alert during incubation. The abstract states these behavioral changes were unlikely to directly explain previously reported differences in growth/fledging success or hatching success in the EMF group.</p>
<p><small>DOI: 10.1080/009841000156619 · PMID: 10839495</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/10839495/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/10839495/</a></small></p>]]></description>
    </item>
    <item>
      <title>Electromagnetic fields (1.8 GHz) increase the permeability to sucrose of the blood-brain barrier in vitro.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5345</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5345</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:harm</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:in_vitro</category>
      <description><![CDATA[<p><strong>Effect:</strong> Harm &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> in_vitro</p>
<p><small>Bioelectromagnetics · 2000 · PubMed</small></p>
<p>In a co-culture in vitro BBB model (rat astrocytes with porcine brain capillary endothelial cells), exposure to GSM1800-standard EMF (1.8 GHz) significantly increased permeability to (14)C-sucrose compared with identically cultured unexposed samples.</p>
<p><small>PMID: 10899769</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/10899769/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/10899769/</a></small></p>]]></description>
    </item>
    <item>
      <title>Hatching in zebrafish (Danio rerio) embryos exposed to a 50 Hz magnetic field.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5344</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5344</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:mixed</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> Mixed &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>Bioelectromagnetics · 2000 · PubMed</small></p>
<p>Zebrafish embryos exposed intra ovo to a 50 Hz AC magnetic field (1000 microT rms) showed a statistically significant delay in hatching when exposure began 48 hours after fertilization. When exposure began 2 hours after fertilization, no statistically significant effect on hatching was observed. Co-exposure with submaximal progesterone doses at 48 hours postfertilization appeared to delay hatching additively.</p>
<p><small>DOI: 10.1002/1521-186x(200007)21:5&lt;407::aid-bem10&gt;3.0.co;2-v · PMID: 10899777</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/10899777/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/10899777/</a></small></p>]]></description>
    </item>
    <item>
      <title>Effects of an in vivo 60 Hz magnetic field on monoamine levels in mouse brain.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5343</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5343</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:mixed</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> Mixed &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>Pathophysiology : the official journal of the International Society for Pathophysiology · 2000 · PubMed</small></p>
<p>Across several exposure models (7 days vertical; 84 days horizontal; 6 h acute in SAM-P8 at multiple ages), monoamine or metabolite levels were not changed by 60 Hz, 10 Gauss exposure, except in a restrained-mouse model. In restrained mice exposed for 1 h, DOPAC increased in hippocampus and hypothalamus, HVA increased in hypothalamus, and 5-HIAA increased in hippocampus and thalamus-midbrain; restraint without EMF did not change these metabolites.</p>
<p><small>DOI: 10.1016/s0928-4680(00)00037-7 · PMID: 10927190</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/10927190/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/10927190/</a></small></p>]]></description>
    </item>
    <item>
      <title>Enhancement of nitric oxide generation by low frequency electromagnetic field.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5342</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5342</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:harm</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> Harm &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>Pathophysiology : the official journal of the International Society for Pathophysiology · 2000 · PubMed</small></p>
<p>In mice, exposure to a 0.1 mT, 60 Hz electromagnetic field did not induce nitric oxide (NO) generation by itself, but significantly enhanced lipopolysaccharide (LPS)-induced NO generation in vivo as measured by ESR spectra of NO adducts in liver.</p>
<p><small>DOI: 10.1016/s0928-4680(00)00040-7 · PMID: 10927193</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/10927193/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/10927193/</a></small></p>]]></description>
    </item>
    <item>
      <title>[Species specificity, age factors, and various neurochemical correlates of the animal spontaneous behavior after exposure to electromagnetic field of the ultralow intensity].</title>
      <link>https://rfsafe.org/mel/paper.php?id=5341</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5341</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:harm</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> Harm &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova · 2000 · PubMed</small></p>
<p>In mice and rats of different ages, ultralow-intensity EMF exposure (4200 and 970 MHz; quasistochastic modulation 20–20,000 Hz; power density 15 microW/cm2; specific body absorption up to 4.5 mJ/kg) generally inhibited locomotor and exploratory activity in the open-field test. Behavioral changes were accompanied by neurochemical shifts described as activation of the serotoninergic system and inhibition of the norepinephrinergic system; species- and age-specific features were reported to dominate, and lower EMF frequency intensified the behavioral effect.</p>
<p><small>PMID: 10984915</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/10984915/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/10984915/</a></small></p>]]></description>
    </item>
    <item>
      <title>Cellular phone electromagnetic field effects on bioelectric activity of human brain.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5340</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5340</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:mixed</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:randomized_trial</category>
      <description><![CDATA[<p><strong>Effect:</strong> Mixed &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> randomized_trial</p>
<p><small>Critical reviews in biomedical engineering · 2000 · PubMed</small></p>
<p>In EEG recordings from 24 volunteers, the multichannel (global) correlation dimension significantly increased during cellular phone EMF exposure and in the post-exposure period, with a more pronounced effect during the &quot;eyes closed&quot; condition.</p>
<p><small>DOI: 10.1615/critrevbiomedeng.v28.i12.450 · PMID: 10999398</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/10999398/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/10999398/</a></small></p>]]></description>
    </item>
    <item>
      <title>Recommended minimal requirements and development guidelines for exposure setups of bio-experiments addressing the health risk concern of wireless communications.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5339</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5339</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:unclear</category>
      <category>evidence:insufficient</category>
      <category>year:2000</category>
      <category>study_type:engineering</category>
      <description><![CDATA[<p><strong>Effect:</strong> Unclear &nbsp; <strong>Evidence:</strong> Insufficient</p>
<p><strong>Study type:</strong> engineering</p>
<p><small>Bioelectromagnetics · 2000 · PubMed</small></p>
<p>The paper argues that existing evidence on potential health effects of EMF exposure is often inadequate for health risk assessment due in part to incomplete exposure descriptions and poorly characterized dosimetry. It lists basic requirements and provides guidelines for evaluating, optimizing, constructing, and verifying exposure setups, and suggests minimum performance requirements for setups relevant to wireless communications.</p>
<p><small>DOI: 10.1002/1521-186x(200010)21:7&lt;508::aid-bem4&gt;3.0.co;2-f · PMID: 11015115</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11015115/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11015115/</a></small></p>]]></description>
    </item>
    <item>
      <title>Effect of electromagnetic field exposure on chemically induced differentiation of friend erythroleukemia cells.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5338</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5338</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:harm</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:in_vitro</category>
      <description><![CDATA[<p><strong>Effect:</strong> Harm &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> in_vitro</p>
<p><small>Environmental health perspectives · 2000 · PubMed</small></p>
<p>Exposure to 60 Hz ELF-EMF produced a dose-dependent inhibition of chemically induced differentiation, with maximal inhibition reported as 40% at 40 mG (4 µT). ELF-EMF at 1.0 G (100 µT) and 10.0 G (1,000 µT) increased cell proliferation by 50% versus sham, and exposure to 0.5 G (50 µT) attenuated the decrease in telomerase activity seen with differentiation under sham conditions.</p>
<p><small>DOI: 10.1289/ehp.00108967 · PMID: 11049817</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11049817/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11049817/</a></small></p>]]></description>
    </item>
    <item>
      <title>Lyn and syk tyrosine kinases are not activated in B-lineage lymphoid cells exposed to low-energy electromagnetic fields.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5337</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5337</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:no_effect</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:in_vitro</category>
      <description><![CDATA[<p><strong>Effect:</strong> No effect &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> in_vitro</p>
<p><small>FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2000 · PubMed</small></p>
<p>In blinded, carefully controlled experiments, exposure to a 100 microT 60 Hz AC magnetic field (with and without a 46 microT DC magnetic field) produced no significant effects on Lyn or Syk tyrosine kinase activities or on protein tyrosine phosphorylation in Nalm-6 and DT40 B cells.</p>
<p><small>DOI: 10.1096/fj.00-0164com · PMID: 11053250</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11053250/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11053250/</a></small></p>]]></description>
    </item>
    <item>
      <title>Evaluation of the effects of extremely low frequency electromagnetic fields on mammalian follicle development.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5336</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5336</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:harm</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:in_vitro</category>
      <description><![CDATA[<p><strong>Effect:</strong> Harm &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> in_vitro</p>
<p><small>Human reproduction (Oxford, England) · 2000 · PubMed</small></p>
<p>Mouse pre-antral follicles cultured for 5 days and exposed to pulsed ELF-EMF at 33 or 50 Hz showed no growth effect over 3 days; by day 5, growth was significantly reduced at 33 Hz versus controls, while 50 Hz was not significantly different. Antrum formation was markedly reduced at both frequencies (controls 79±3% vs 30±6% at 33 Hz and 51.6±4% at 50 Hz), with failed antrum formation associated with lower oestradiol release and granulosa cell DNA synthesis; these effects were not related to granulosa cell apoptosis. Oocytes from exposed follicles had reduced ability to resume meiotic maturation compared with controls.</p>
<p><small>DOI: 10.1093/humrep/15.11.2319 · PMID: 11056125</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11056125/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11056125/</a></small></p>]]></description>
    </item>
    <item>
      <title>Digression on chemical electromagnetic field effects in membrane signal transduction--cooperativity paradigm of the acetylcholine receptor.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5335</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5335</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:unclear</category>
      <category>evidence:insufficient</category>
      <category>year:2000</category>
      <category>study_type:review</category>
      <description><![CDATA[<p><strong>Effect:</strong> Unclear &nbsp; <strong>Evidence:</strong> Insufficient</p>
<p><strong>Study type:</strong> review</p>
<p><small>Bioelectrochemistry (Amsterdam, Netherlands) · 2000 · PubMed</small></p>
<p>The article argues that equilibrium and rate constants are only sensitive to external fields when reaction moments (ΔM) are finite, and that small local EMF-induced shifts in K and k would require amplification to become effective. It proposes structural/functional cooperativity (illustrated with the acetylcholine receptor) as a mechanism that could amplify small field effects on proteins involved in signal transduction, and discusses membrane field amplification and electric field pulses for transient permeabilization.</p>
<p><small>DOI: 10.1016/s0302-4598(00)00082-9 · PMID: 11059576</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11059576/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11059576/</a></small></p>]]></description>
    </item>
    <item>
      <title>Exposure to pulsed high-frequency electromagnetic field during waking affects human sleep EEG.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5334</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5334</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:mixed</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:randomized_trial</category>
      <description><![CDATA[<p><strong>Effect:</strong> Mixed &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> randomized_trial</p>
<p><small>Neuroreport · 2000 · PubMed</small></p>
<p>Compared with sham exposure, 30 min exposure to 900 MHz EMF (spatial peak SAR 1 W/kg) during waking was associated with increased EEG spectral power during subsequent non-rapid eye movement sleep, with the maximum rise in the 9.75–11.25 Hz and 12.5–13.25 Hz bands early in sleep. Unilateral exposure did not induce hemispheric asymmetry of EEG power.</p>
<p><small>DOI: 10.1097/00001756-200010200-00012 · PMID: 11059895</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11059895/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11059895/</a></small></p>]]></description>
    </item>
    <item>
      <title>Human sleep EEG under the influence of pulsed radio frequency electromagnetic fields. Results from polysomnographies using submaximal high power flux densities.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5333</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5333</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:no_effect</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:randomized_trial</category>
      <description><![CDATA[<p><strong>Effect:</strong> No effect &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> randomized_trial</p>
<p><small>Neuropsychobiology · 2000 · PubMed</small></p>
<p>In 20 healthy male subjects undergoing all-night polysomnography with and without exposure to a circularly polarized GSM-like RF EMF (900 MHz, pulsed at 217 Hz; power flux density 50 W/m^2), no significant effects were found on conventional sleep parameters or sleep EEG power spectra.</p>
<p><small>DOI: 10.1159/000026695 · PMID: 11096337</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11096337/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11096337/</a></small></p>]]></description>
    </item>
    <item>
      <title>Prenatal exposure to 900 MHz, cell-phone electromagnetic fields had no effect on operant-behavior performances of adult rats.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5332</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5332</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:no_effect</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> No effect &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>Bioelectromagnetics · 2000 · PubMed</small></p>
<p>Pregnant Wistar rats were continuously exposed during pregnancy to a low-level 900 MHz, 217 Hz pulse-modulated GSM-like field (0.1 mW/cm^2; modeled whole-body average SAR range 17.5–75 mW/kg). Analyses of adult offspring operant performance scores and IRI patterns found no measurable cognitive deficits from in-utero exposure compared with sham exposure.</p>
<p><small>PMID: 11102946</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11102946/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11102946/</a></small></p>]]></description>
    </item>
    <item>
      <title>The effect of pulsed electromagnetic fields on the physiologic behaviour of a human astrocytoma cell line.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5331</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5331</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:mixed</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:in_vitro</category>
      <description><![CDATA[<p><strong>Effect:</strong> Mixed &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> in_vitro</p>
<p><small>Biochimica et biophysica acta · 2000 · PubMed</small></p>
<p>Exposure to 50 Hz pulsed EMFs (peak magnetic field 3 mT) for 24 h significantly increased basal intracellular Ca2+ from 124±51 nM to 200±79 nM. With substance P pretreatment, [Ca2+]i increased to 555±278 nM, while EMF exposure significantly reduced it to 327±146 nM; IL-6 levels were reported to be ~40% higher than controls immediately after exposure and 24 h later, and proliferative responses increased slightly.</p>
<p><small>DOI: 10.1016/s0167-4889(00)00111-7 · PMID: 11118642</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11118642/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11118642/</a></small></p>]]></description>
    </item>
    <item>
      <title>Effects of electromagnetic fields emitted by cellular phones on the electroencephalogram during a visual working memory task.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5330</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5330</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:mixed</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:randomized_trial</category>
      <description><![CDATA[<p><strong>Effect:</strong> Mixed &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> randomized_trial</p>
<p><small>International journal of radiation biology · 2000 · PubMed</small></p>
<p>Exposure to a digital 902 MHz EMF altered ERD/ERS responses in the 6–8 Hz and 8–10 Hz EEG bands, but effects were observed only when analyzed by working memory load and depended on whether stimuli were targets. The authors conclude EMF exposure modulates ~8 Hz EEG oscillatory responses during cognitive processing.</p>
<p><small>DOI: 10.1080/09553000050201154 · PMID: 11133048</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11133048/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11133048/</a></small></p>]]></description>
    </item>
    <item>
      <title>The effect of electromagnetic field exposure on the formation of DNA lesions.</title>
      <link>https://rfsafe.org/mel/paper.php?id=5329</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=5329</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:harm</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:in_vitro</category>
      <description><![CDATA[<p><strong>Effect:</strong> Harm &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> in_vitro</p>
<p><small>Redox report : communications in free radical research · 2000 · PubMed</small></p>
<p>SnCl2-treated pBR322 plasmids exposed to EMF showed an EMF-dependent potentiation of DNA scission (appearance of relaxed plasmids). Plasmids pre-exposed to EMF were less capable of transforming Escherichia coli, and the authors conclude EMF in the presence of a transition metal can cause DNA damage.</p>
<p><small>DOI: 10.1179/135100000101535843 · PMID: 11145105</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11145105/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11145105/</a></small></p>]]></description>
    </item>
    <item>
      <title>[Use of transcutaneous laser biostimulation of blood and a running alternating magnetic field in preparing periodontitis patients for surgery].</title>
      <link>https://rfsafe.org/mel/paper.php?id=3992</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=3992</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:benefit</category>
      <category>evidence:very_low</category>
      <category>year:2000</category>
      <category>study_type:other</category>
      <description><![CDATA[<p><strong>Effect:</strong> Benefit &nbsp; <strong>Evidence:</strong> Very low</p>
<p><strong>Study type:</strong> other</p>
<p><small>Stomatologiia · 2000 · PubMed</small></p>
<p>In 103 patients, use of a running alternating magnetic field (ATOS device) and transcutaneous laser biostimulation of blood was reported to accelerate preoperative treatment and to allow periodontal operations to be performed in an optimal status under conditions of improved organism defense forces.</p>
<p><small>PMID: 11186560</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11186560/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11186560/</a></small></p>]]></description>
    </item>
    <item>
      <title>Correcting errors in eye-position data arising from the distortion of magnetic fields by display devices.</title>
      <link>https://rfsafe.org/mel/paper.php?id=3991</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=3991</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:unclear</category>
      <category>evidence:insufficient</category>
      <category>year:2000</category>
      <category>study_type:engineering</category>
      <description><![CDATA[<p><strong>Effect:</strong> Unclear &nbsp; <strong>Evidence:</strong> Insufficient</p>
<p><strong>Study type:</strong> engineering</p>
<p><small>Behavior research methods, instruments, &amp; computers : a journal of the Psychonomic Society, Inc · 2000 · PubMed</small></p>
<p>Point-of-gaze errors can occur when a reader leans toward a display device with large metal masses, because the metal distorts magnetic fields and produces false magnetic sensor data. The authors describe a cheaper correction method using a fixture to hold the magnetic sensor in identical positions with and without the distorting effect.</p>
<p><small>DOI: 10.3758/bf03200830 · PMID: 11189858</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11189858/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11189858/</a></small></p>]]></description>
    </item>
    <item>
      <title>Magnetic fields with photon beams: Monte Carlo calculations for a model magnetic field.</title>
      <link>https://rfsafe.org/mel/paper.php?id=3990</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=3990</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:mixed</category>
      <category>evidence:insufficient</category>
      <category>year:2000</category>
      <category>study_type:other</category>
      <description><![CDATA[<p><strong>Effect:</strong> Mixed &nbsp; <strong>Evidence:</strong> Insufficient</p>
<p><strong>Study type:</strong> other</p>
<p><small>Medical physics · 2000 · PubMed</small></p>
<p>EGS4 Monte Carlo calculations in a water phantom suggest strong transverse magnetic fields (nominal center strength B0 1–5 T; max within beam 2.2×B0) can produce localized dose enhancements and corresponding distal dose reductions for 15, 30, and 45 MV photon beams. Significant enhancement occurred at B0=2 T and increased greatly at B0=3 T; stronger fields further increased enhancement only for the 45 MV beam. Example results: for 30 MV with B0=3 T, dose enhancement was 55% (narrow), 32% (medium ~2 cm), and 23% (large ~4 cm) peak-width configurations; dose reductions were ~30% for 30 MV configurations and ~40% for 45 MV configurations.</p>
<p><small>DOI: 10.1118/1.1326447 · PMID: 11190956</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11190956/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11190956/</a></small></p>]]></description>
    </item>
    <item>
      <title>Radiofrequency volumetric tissue reduction (RFVTR) of inferior turbinates: a new method in the treatment of chronic nasal obstruction.</title>
      <link>https://rfsafe.org/mel/paper.php?id=3985</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=3985</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:benefit</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:other</category>
      <description><![CDATA[<p><strong>Effect:</strong> Benefit &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> other</p>
<p><small>American journal of rhinology · 2000 · PubMed</small></p>
<p>Three months after radiofrequency volumetric tissue reduction of both inferior turbinates, 20/22 patients (91%) reported subjective improvement in nasal patency. Average cross-sectional area (both sides, C-Notch before decongestion) increased in 15/22 patients (68.2%), with a significant mean increase from 1.24 to 1.49 cm2 (p=0.0054). Postoperative edema resolved within the first week.</p>
<p><small>DOI: 10.2500/105065800779954257 · PMID: 11197110</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11197110/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11197110/</a></small></p>]]></description>
    </item>
    <item>
      <title>[Use of super-high frequency electromagnetic fields on intrarenal circulation and morphological status of health kidneys (experimental study)].</title>
      <link>https://rfsafe.org/mel/paper.php?id=3984</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=3984</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:harm</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> Harm &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury · 2000 · PubMed</small></p>
<p>In female rats, decimetric electromagnetic waves produced a marked hemodynamic effect with redistribution of intrarenal circulation. Exposure at 395 mW/cm2 was associated with dysregulation of intrarenal blood flow and morphological changes including hemodynamic disorders, flebostasis, stromal edema, tubular epithelial dystrophy, and periglomerular sclerosis with aseptic interstitial inflammation; prostaglandin E2 levels in renal papilla tissue were reported as supporting evidence.</p>
<p><small>PMID: 11197654</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11197654/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11197654/</a></small></p>]]></description>
    </item>
    <item>
      <title>Temperature-controlled radiofrequency tissue volume reduction of the soft palate (somnoplasty) in the treatment of habitual snoring: results of a European multicenter trial.</title>
      <link>https://rfsafe.org/mel/paper.php?id=3983</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=3983</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:benefit</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:other</category>
      <description><![CDATA[<p><strong>Effect:</strong> Benefit &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> other</p>
<p><small>Acta oto-laryngologica · 2000 · PubMed</small></p>
<p>In a prospective, non-randomized European multicenter clinical study of 45 nonapneic snorers, temperature-controlled radiofrequency treatment of the soft palate significantly improved the snoring index (7.6 ± 2.1 to 4.1 ± 2.9; p&lt;0.001) and Epworth Sleepiness Score (8.5 ± 5.0 to 6.0 ± 4.3; p=0.001). No major adverse events were reported and postoperative pain was minimal; 45% achieved a post-treatment snoring index &lt;3 and 84% reported improvement.</p>
<p><small>DOI: 10.1080/00016480050218735 · PMID: 11200595</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11200595/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11200595/</a></small></p>]]></description>
    </item>
    <item>
      <title>Extremely low frequency magnetic fields in residences in Germany. Distribution of measurements, comparison of two methods for assessing exposure, and predictors for the occurrence of magnetic fields above background level.</title>
      <link>https://rfsafe.org/mel/paper.php?id=3982</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=3982</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:unclear</category>
      <category>evidence:moderate</category>
      <category>year:2000</category>
      <category>study_type:exposure_assessment</category>
      <description><![CDATA[<p><strong>Effect:</strong> Unclear &nbsp; <strong>Evidence:</strong> Moderate</p>
<p><strong>Study type:</strong> exposure_assessment</p>
<p><small>Radiation and environmental biophysics · 2000 · PubMed</small></p>
<p>Across 1,835 measurements in German residences (1997–1999), median 50 Hz magnetic fields &gt;0.2 µT were infrequent (1.4% of residences). Among 25 residences within 50 m of high-voltage power lines (123–420 kV), the median field exceeded 0.2 µT in 8 (32%). 24 h measurements correlated well with spot measurements (r&gt;0.7), but agreement was poor when dichotomizing at 0.2 µT; apartment buildings had higher measured fields, with some evidence of positive correlation with traffic density and inverse association with family net income.</p>
<p><small>DOI: 10.1007/s004110000068 · PMID: 11200967</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11200967/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11200967/</a></small></p>]]></description>
    </item>
    <item>
      <title>Application of capacitively coupled electric field enhances periimplant osteogenesis in the dog mandible.</title>
      <link>https://rfsafe.org/mel/paper.php?id=3979</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=3979</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:benefit</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> Benefit &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>The International journal of prosthodontics · 2000 · PubMed</small></p>
<p>Daily application of capacitively coupled electric field (10-Vp-p, 60-kHz sine wave; 8 h/day) significantly increased the bone-contact ratio at 14, 21, and 30 days after implant placement compared with controls. Bone-area ratios at 14 and 21 days were significantly larger than controls and were similar to those of a 90-day control group.</p>
<p><small>PMID: 11203655</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11203655/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11203655/</a></small></p>]]></description>
    </item>
    <item>
      <title>Splice isoforms of transcription factor Elf-1 affecting its regulatory function in transcription-molecular cloning of rat Elf-1.</title>
      <link>https://rfsafe.org/mel/paper.php?id=3978</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=3978</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:unclear</category>
      <category>evidence:insufficient</category>
      <category>year:2000</category>
      <category>study_type:in_vitro</category>
      <description><![CDATA[<p><strong>Effect:</strong> Unclear &nbsp; <strong>Evidence:</strong> Insufficient</p>
<p><strong>Study type:</strong> in_vitro</p>
<p><small>Bioscience, biotechnology, and biochemistry · 2000 · PubMed</small></p>
<p>Rat Elf-1 cDNAs were cloned and two splice isoforms were identified in addition to full-length Elf-1. In a transient coexpression system, overexpression of rat Elf-1 type 1 inhibited alpha chain promoter activity; type 2 showed lower inhibitory activity than type 1, and type 3 showed no inhibitory effect.</p>
<p><small>DOI: 10.1271/bbb.64.2601 · PMID: 11210123</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11210123/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11210123/</a></small></p>]]></description>
    </item>
    <item>
      <title>Exposure to strong magnetic fields at power frequency potentiates X-ray-induced DNA strand breaks.</title>
      <link>https://rfsafe.org/mel/paper.php?id=3977</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=3977</guid>
      <pubDate>Sat, 01 Jan 2000 00:00:00 +0000</pubDate>
      <category>effect:mixed</category>
      <category>evidence:low</category>
      <category>year:2000</category>
      <category>study_type:in_vitro</category>
      <description><![CDATA[<p><strong>Effect:</strong> Mixed &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> in_vitro</p>
<p><small>Journal of radiation research · 2000 · PubMed</small></p>
<p>In MO54 cells, ELFMF exposure alone (5, 50, 400 mT) did not significantly change comet assay tail moment versus control up to 400 mT. X-rays (5 Gy) increased DNA strand breaks, and subsequent ELFMF exposure at 50 and 400 mT (at 4°C/on ice) significantly increased tail moment compared with X-rays alone; at 37°C, no significant difference was observed between X-rays alone and X-rays plus 400 mT.</p>
<p><small>DOI: 10.1269/jrr.41.293 · PMID: 11210830</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/11210830/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/11210830/</a></small></p>]]></description>
    </item>
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