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    <title>Reviewed Papers — 1988</title>
    <link>https://rfsafe.org/mel/papers_class.php?year=1988</link>
    <description>Reviewed papers published in 1988.</description>
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    <item>
      <title>Kinetics of channelized membrane ions in magnetic fields</title>
      <link>https://rfsafe.org/mel/paper.php?id=6697</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6697</guid>
      <pubDate>Fri, 01 Jan 1988 00:00:00 +0000</pubDate>
      <category>effect:unclear</category>
      <category>evidence:insufficient</category>
      <category>year:1988</category>
      <category>study_type:other</category>
      <description><![CDATA[<p><strong>Effect:</strong> Unclear &nbsp; <strong>Evidence:</strong> Insufficient</p>
<p><strong>Study type:</strong> other</p>
<p><small>Bioelectromagnetics · 1988 · Manual</small></p>
<p>A cyclotron resonance model for channel ion transport in weak magnetic fields was extended to include damping losses and used to derive conductivity tensors for different electric-field configurations. Model behavior near the cyclotron resonance frequency was compared to existing Ca2+ efflux data; under an assumption of K+ ions transiting in a 0.35 G field, a collision time of 0.023 s was obtained and a mean kinetic energy of 3.5 eV at resonance was estimated. The model predicts discrete vibrational modes (harmonics) with eigenfrequencies ωn = nωc, stated to be compatible with some prior observations, though noting an exception regarding absence of even modes in those observations.</p>
<p><small>DOI: 10.1002/bem.2250090104 · PMID: 2449894</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/2449894/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/2449894/</a></small></p>]]></description>
    </item>
    <item>
      <title>Influence of electromagnetic fields on the efflux of calcium ions from brain tissue in vitro: a three-model analysis consistent with the frequency response up to 510 Hz</title>
      <link>https://rfsafe.org/mel/paper.php?id=6675</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6675</guid>
      <pubDate>Fri, 01 Jan 1988 00:00:00 +0000</pubDate>
      <category>effect:mixed</category>
      <category>evidence:low</category>
      <category>year:1988</category>
      <category>study_type:in_vitro</category>
      <description><![CDATA[<p><strong>Effect:</strong> Mixed &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> in_vitro</p>
<p><small>Bioelectromagnetics · 1988 · Manual</small></p>
<p>Calcium-ion efflux from chicken brain tissues was examined across 1–510 Hz (15-Hz intervals) with 15 Vrms/m electric field and 59–69 nTrms magnetic field. Differences in mean efflux between exposed and sham samples did not show readily discernible frequency-response patterns, but analyses of calculated P-values were used to hypothesize three possible frequency-dependent patterns, including significant responses (P&lt;.01) at some frequencies (e.g., at 30-Hz intervals between 15 and 315 Hz with exceptions at 165 Hz; significant results at 60, 90, and 180 Hz but not 300 Hz; and one significant response at 405 Hz).</p>
<p><small>DOI: 10.1002/bem.2250090303 · PMID: 3178897</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/3178897/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/3178897/</a></small></p>]]></description>
    </item>
    <item>
      <title>Microwave effects on acetylcholine-induced channels in cultured chick myotubes</title>
      <link>https://rfsafe.org/mel/paper.php?id=6669</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6669</guid>
      <pubDate>Fri, 01 Jan 1988 00:00:00 +0000</pubDate>
      <category>effect:harm</category>
      <category>evidence:low</category>
      <category>year:1988</category>
      <category>study_type:in_vitro</category>
      <description><![CDATA[<p><strong>Effect:</strong> Harm &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> in_vitro</p>
<p><small>Bioelectromagnetics · 1988 · Manual</small></p>
<p>During exposure to low-power microwaves, the frequency of ACh-activated single-channel openings decreased and the ACh-induced total current showed a faster falling phase. Channel open time and conductance were reported as not affected; the authors conclude microwaves increased desensitization rate and decreased channel opening probability.</p>
<p><small>DOI: 10.1002/bem.2250090406 · PMID: 2461204</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/2461204/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/2461204/</a></small></p>]]></description>
    </item>
    <item>
      <title>Some behavioral effects of short-term exposure of rats to 2.45 GHz microwave radiation.</title>
      <link>https://rfsafe.org/mel/paper.php?id=6244</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6244</guid>
      <pubDate>Fri, 01 Jan 1988 00:00:00 +0000</pubDate>
      <category>effect:mixed</category>
      <category>evidence:low</category>
      <category>year:1988</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> Mixed &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>Bioelectromagnetics · 1988 · PubMed</small></p>
<p>Rats exposed to 2.45 GHz continuous-wave microwave radiation (10 mW/cm2 for 7 h) showed reduced locomotor activity and reduced responsiveness to repeated acoustic startle stimuli compared with sham-exposed animals. Microwave exposure had no effect on retention of a passive avoidance procedure when tested 1 week after training.</p>
<p><small>DOI: 10.1002/bem.2250090307 · PMID: 3178900</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/3178900/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/3178900/</a></small></p>]]></description>
    </item>
    <item>
      <title>Effect of radiofrequency radiation on mRNA expression in cultured rodent cells.</title>
      <link>https://rfsafe.org/mel/paper.php?id=6243</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6243</guid>
      <pubDate>Fri, 01 Jan 1988 00:00:00 +0000</pubDate>
      <category>effect:no_effect</category>
      <category>evidence:low</category>
      <category>year:1988</category>
      <category>study_type:in_vitro</category>
      <description><![CDATA[<p><strong>Effect:</strong> No effect &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> in_vitro</p>
<p><small>Physiological chemistry and physics and medical NMR · 1988 · PubMed</small></p>
<p>Across four rodent cell lines and the DNA probes used (oncogenes, heat shock protein, long terminal repeat sequences), no significant differences in mRNA expression were observed between microwave-exposed and sham-exposed samples.</p>
<p><small>PMID: 3222348</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/3222348/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/3222348/</a></small></p>]]></description>
    </item>
    <item>
      <title>Reduced exposure to microwave radiation by rats: frequency specific effects.</title>
      <link>https://rfsafe.org/mel/paper.php?id=6242</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6242</guid>
      <pubDate>Fri, 01 Jan 1988 00:00:00 +0000</pubDate>
      <category>effect:harm</category>
      <category>evidence:low</category>
      <category>year:1988</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> Harm &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>Progress in clinical and biological research · 1988 · PubMed</small></p>
<p>Rats reduced occupancy of a preferred cage side when occupancy triggered microwave exposure, resulting in reduced exposure. Avoidance/reduced exposure differed by frequency: 360 MHz and 2450 MHz at 1, 2, 6, and 10 W/kg were significantly different from 700 MHz. In semichronic exposures, the threshold for reduced exposure at 2450 MHz was between whole-body SARs of 2.1 and 2.8 W/kg.</p>
<p><small>PMID: 3344273</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/3344273/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/3344273/</a></small></p>]]></description>
    </item>
    <item>
      <title>B16 melanoma development in black mice exposed to low-level microwave radiation.</title>
      <link>https://rfsafe.org/mel/paper.php?id=6241</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6241</guid>
      <pubDate>Fri, 01 Jan 1988 00:00:00 +0000</pubDate>
      <category>effect:no_effect</category>
      <category>evidence:low</category>
      <category>year:1988</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> No effect &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>Bioelectromagnetics · 1988 · PubMed</small></p>
<p>In black C57/6J mice with B16 melanoma, low-level 2,450 MHz microwave exposure (1 mW/cm2; SAR 1.2 mW/g) for up to 690 hours showed no significant effects on tumor development or survival compared with controls. No significant differences were observed between continuous-wave and pulsed-wave exposure.</p>
<p><small>DOI: 10.1002/bem.2250090110 · PMID: 3345211</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/3345211/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/3345211/</a></small></p>]]></description>
    </item>
    <item>
      <title>[Effect of electromagnetic radiation of radio frequency (340 and 800 MHz) on liposomes from dimyristoyl lecithin].</title>
      <link>https://rfsafe.org/mel/paper.php?id=6240</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6240</guid>
      <pubDate>Fri, 01 Jan 1988 00:00:00 +0000</pubDate>
      <category>effect:mixed</category>
      <category>evidence:very_low</category>
      <category>year:1988</category>
      <category>study_type:in_vitro</category>
      <description><![CDATA[<p><strong>Effect:</strong> Mixed &nbsp; <strong>Evidence:</strong> Very low</p>
<p><strong>Study type:</strong> in_vitro</p>
<p><small>Biofizika · 1988 · PubMed</small></p>
<p>In dimyristoyl lecithin liposomes prepared below the phase-transition temperature, annealing induced by 340- and 800-MHz microwave radiation required less integral heating than expected based on thermostat heating experiments.</p>
<p><small>PMID: 3370244</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/3370244/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/3370244/</a></small></p>]]></description>
    </item>
    <item>
      <title>Studies of the induction of dominant lethals and translocations in male mice after chronic exposure to microwave radiation.</title>
      <link>https://rfsafe.org/mel/paper.php?id=6239</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6239</guid>
      <pubDate>Fri, 01 Jan 1988 00:00:00 +0000</pubDate>
      <category>effect:no_effect</category>
      <category>evidence:low</category>
      <category>year:1988</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> No effect &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>International journal of radiation biology and related studies in physics, chemistry, and medicine · 1988 · PubMed</small></p>
<p>Male mice chronically exposed to 2.45 GHz continuous-wave microwaves (100 W m-2; SAR ~4 W/kg) showed no significant differences versus sham controls in pregnancy rate, preimplantation survival, or postimplantation survival. Cytogenetic analysis found no differences in reciprocal translocations or univalents; low levels of fragments/exchanges occurred in both groups, and the authors concluded no evidence of male germ-cell mutagenesis under these conditions.</p>
<p><small>DOI: 10.1080/09553008814551341 · PMID: 3259564</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/3259564/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/3259564/</a></small></p>]]></description>
    </item>
    <item>
      <title>[K+,H+ and Cl- fluxes across erythrocyte membrane irradiated with radio frequency electromagnetic fields].</title>
      <link>https://rfsafe.org/mel/paper.php?id=6238</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6238</guid>
      <pubDate>Fri, 01 Jan 1988 00:00:00 +0000</pubDate>
      <category>effect:harm</category>
      <category>evidence:low</category>
      <category>year:1988</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> Harm &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>Biofizika · 1988 · PubMed</small></p>
<p>Exposure to 460 MHz microwave radiation (SAR 280 W/kg) produced the most significant changes in the K+ transport system of isolated rat erythrocytes, including increased K+ loss during treatment and a 2-fold decrease in the rate of K+ efflux under specified incubation conditions. Similar changes occurred with conventional heating to 39°C for 20 minutes, and the authors conclude the microwave effects were temperature-induced membrane structural changes affecting potassium transport.</p>
<p><small>PMID: 2465027</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/2465027/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/2465027/</a></small></p>]]></description>
    </item>
    <item>
      <title>[Effect of microwave radiation on morphology and histochemical changes in rat epididymis].</title>
      <link>https://rfsafe.org/mel/paper.php?id=6237</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6237</guid>
      <pubDate>Fri, 01 Jan 1988 00:00:00 +0000</pubDate>
      <category>effect:unknown</category>
      <category>evidence:unknown</category>
      <category>year:1988</category>
      <description><![CDATA[<p><strong>Effect:</strong> Unknown &nbsp; <strong>Evidence:</strong> Unknown</p>
<p><small>Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao · 1988 · PubMed</small></p>
<p><small>PMID: 3253170</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/3253170/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/3253170/</a></small></p>]]></description>
    </item>
    <item>
      <title>In situ fixation of the spinal cord using microwave radiation.</title>
      <link>https://rfsafe.org/mel/paper.php?id=6236</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6236</guid>
      <pubDate>Fri, 01 Jan 1988 00:00:00 +0000</pubDate>
      <category>effect:benefit</category>
      <category>evidence:insufficient</category>
      <category>year:1988</category>
      <category>study_type:other</category>
      <description><![CDATA[<p><strong>Effect:</strong> Benefit &nbsp; <strong>Evidence:</strong> Insufficient</p>
<p><strong>Study type:</strong> other</p>
<p><small>Journal of neurosurgery · 1988 · PubMed</small></p>
<p>The report states that microwave irradiation of the spinal cord before removal from the spine provides a rapid and easy method of tissue fixation, with an absence of artifacts comparable to perfusion fixation.</p>
<p><small>DOI: 10.3171/jns.1988.69.5.0719 · PMID: 3183733</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/3183733/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/3183733/</a></small></p>]]></description>
    </item>
    <item>
      <title>Plasma corticosterone in hemorrhaged Japanese quail after microwave irradiation in ovo.</title>
      <link>https://rfsafe.org/mel/paper.php?id=6235</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6235</guid>
      <pubDate>Fri, 01 Jan 1988 00:00:00 +0000</pubDate>
      <category>effect:mixed</category>
      <category>evidence:low</category>
      <category>year:1988</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> Mixed &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>Comparative biochemistry and physiology. A, Comparative physiology · 1988 · PubMed</small></p>
<p>Hemorrhage increased plasma corticosterone in both sexes; shams had higher corticosterone than controls. In a separate experiment, eggs irradiated during incubation with 2.45 GHz continuous-wave microwaves produced juvenile males that had higher plasma corticosterone after hemorrhage than nonirradiated males, while no irradiation effect was found in females.</p>
<p><small>DOI: 10.1016/0300-9629(88)91050-x · PMID: 2896572</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/2896572/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/2896572/</a></small></p>]]></description>
    </item>
    <item>
      <title>Serum enzymes in hemorrhaged Japanese quail after microwave irradiation during embryogeny.</title>
      <link>https://rfsafe.org/mel/paper.php?id=6234</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6234</guid>
      <pubDate>Fri, 01 Jan 1988 00:00:00 +0000</pubDate>
      <category>effect:mixed</category>
      <category>evidence:low</category>
      <category>year:1988</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> Mixed &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>Comparative biochemistry and physiology. A, Comparative physiology · 1988 · PubMed</small></p>
<p>Japanese quail eggs exposed in ovo to 2.45 GHz continuous wave microwaves (5 mW/cm2; SAR 4.03 mW/g) during the first 12 days of embryogeny showed no effects on lactate dehydrogenase, beta-glucuronidase, acid phosphatase, glucose, or protein either before or after a 30% blood-volume hemorrhage after hatching. Microwave irradiation during embryogeny affected the response of serum glutamic oxaloacetic transaminase activity to hemorrhagic stress.</p>
<p><small>DOI: 10.1016/0300-9629(88)90828-6 · PMID: 2899471</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/2899471/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/2899471/</a></small></p>]]></description>
    </item>
    <item>
      <title>Microwave effect on camphor binding to rat olfactory epithelium.</title>
      <link>https://rfsafe.org/mel/paper.php?id=6233</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6233</guid>
      <pubDate>Fri, 01 Jan 1988 00:00:00 +0000</pubDate>
      <category>effect:harm</category>
      <category>evidence:low</category>
      <category>year:1988</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> Harm &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>Bioelectromagnetics · 1988 · PubMed</small></p>
<p>Microwave radiation decreased specific camphor binding to a membrane fraction of rat olfactory epithelium, but not to a Triton X-100 extract of the fraction. The inhibition did not depend on modulation frequency (1–100 Hz) and was not a linear function of SAR. The decrease in binding was attributed to shedding/release of the specific camphor-binding protein from the membrane into solution.</p>
<p><small>DOI: 10.1002/bem.2250090404 · PMID: 3190762</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/3190762/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/3190762/</a></small></p>]]></description>
    </item>
    <item>
      <title>Morphological changes in cerebellum of neonatal rats exposed to 2.45 GHz microwaves.</title>
      <link>https://rfsafe.org/mel/paper.php?id=6232</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6232</guid>
      <pubDate>Fri, 01 Jan 1988 00:00:00 +0000</pubDate>
      <category>effect:harm</category>
      <category>evidence:low</category>
      <category>year:1988</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> Harm &nbsp; <strong>Evidence:</strong> Low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>Progress in clinical and biological research · 1988 · PubMed</small></p>
<p>Neonatal rats exposed to 2.45 GHz continuous-wave microwaves (10 mW/cm2; SAR 2 W/kg) showed nearly twice the number of small deeply stained pyknotic cells in the external granular layer compared with sham controls, along with altered Purkinje cell features (finely dispersed Nissl bodies and disordered RER arrays). Some exposed animals showed mononuclear cellular infiltration; electron microscopy described nuclear and cytoplasmic degenerative changes in pyknotic cells with subsequent phagocytosis.</p>
<p><small>PMID: 3344268</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/3344268/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/3344268/</a></small></p>]]></description>
    </item>
    <item>
      <title>Prenatal microwave exposure and behavior.</title>
      <link>https://rfsafe.org/mel/paper.php?id=6231</link>
      <guid isPermaLink="true">https://rfsafe.org/mel/paper.php?id=6231</guid>
      <pubDate>Fri, 01 Jan 1988 00:00:00 +0000</pubDate>
      <category>effect:harm</category>
      <category>evidence:very_low</category>
      <category>year:1988</category>
      <category>study_type:animal</category>
      <description><![CDATA[<p><strong>Effect:</strong> Harm &nbsp; <strong>Evidence:</strong> Very low</p>
<p><strong>Study type:</strong> animal</p>
<p><small>Progress in clinical and biological research · 1988 · PubMed</small></p>
<p>The studies reported results consistent with prenatal microwave exposure producing postnatal behavioral changes, particularly affecting sensitivity to thermally related stimuli or conditions rather than thermally neutral stimuli.</p>
<p><small>PMID: 3344272</small></p>
<p><small><strong>Study URL:</strong> <a href="https://pubmed.ncbi.nlm.nih.gov/3344272/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/3344272/</a></small></p>]]></description>
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