Single exposure to near-threshold 5G millimeter wave modifies restraint stress responses in rats
In a rat experiment (n=59), a single 40-minute whole-body 28 GHz exposure at near-threshold WBA-SAR levels was evaluated under normal and heat conditions with restraint. After accounting for sham-related restraint stress, exposure was associated with increased serum-free corticosterone 1–3 days later, especially when rectal temperature rose by >1°C. Urinary catecholamines suggested an immediate inhibitory effect on stress response (notably noradrenaline), with heat amplifying effects and linking noradrenaline to tail surface temperature.
Key points
- Rats were exposed once to 28 GHz for 40 minutes at WBA-SARs of 0, 3.7, or 7.2 W/kg under normal and heat environmental conditions.
- Sham exposure itself elicited stress responses, attributed mainly to restraint in acrylic holders.
- After adjustment for sham effects, 28 GHz exposure was associated with higher serum-free corticosterone 1 or 3 days after exposure.
- The corticosterone increase was reported as more evident in animals showing >1°C rectal temperature change.
- Urinary catecholamines indicated an inhibitory effect on the immediate post-exposure stress response, particularly for noradrenaline.
- Heat conditions amplified observed effects, and noradrenaline correlated with tail surface temperature, consistent with a role in heat dissipation.
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AI-generated summaries may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.
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