Changes in Mice Brain Spontaneous Electrical Activity during Cortical Spreading Depression due to Mobile Phone Radiation.

Abstract

The objective of the present study was to investigate changes in spontaneous EEG activity during cortical spreading depression (CSD) in mice brain. The cortical region of anaesthetized mice were exposed to the electromagnetic fields (EMFs) emitted from a mobile phone (MP, 935.2-960.2 MHz, 41.8 mW/cm(2)). The effect of EMFs on EEG was investigated before and after exposure to different stimuli (MP, 2% KCl, and MP & 2% KCl). The records of brain spontaneous EEG activity, slow potential changes (SPC), and spindle shaped firings were obtained through an interfaced computer. The results showed increases in the amplitude of evoked spindles by about 87%, 17%, and 226% for MP, 2% KCl, and MP & 2% KCl; respectively, as compared to values for the control group. These results showed that the evoked spindle is a more sensitive indicator of the effect of exposure to EMFs from MP.

AI evidence extraction

Main findings

Anaesthetized mice cortical regions were exposed to mobile phone EMFs (935.2–960.2 MHz; 41.8 mW/cm^2). The study reported increases in the amplitude of evoked spindles by about 87% (mobile phone), 17% (2% KCl), and 226% (mobile phone & 2% KCl) compared with control, and suggested evoked spindle amplitude was a sensitive indicator of EMF exposure effects.

Outcomes measured

• Spontaneous EEG activity
• Cortical spreading depression (CSD)-related measures
• Slow potential changes (SPC)
• Spindle-shaped firings (evoked spindle amplitude)

Limitations

• Sample size not reported in the abstract
• Exposure duration not reported in the abstract
• No SAR reported in the abstract
• Details of control conditions and statistical testing are not provided in the abstract

Suggested hubs

• mobile-phones-rf (0.9)
  Exposure source is a mobile phone emitting RF EMFs; EEG outcomes assessed in mice.

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    "study_type": "animal",
    "exposure": {
        "band": "RF",
        "source": "mobile phone",
        "frequency_mhz": null,
        "sar_wkg": null,
        "duration": null
    },
    "population": "Anaesthetized mice",
    "sample_size": null,
    "outcomes": [
        "Spontaneous EEG activity",
        "Cortical spreading depression (CSD)-related measures",
        "Slow potential changes (SPC)",
        "Spindle-shaped firings (evoked spindle amplitude)"
    ],
    "main_findings": "Anaesthetized mice cortical regions were exposed to mobile phone EMFs (935.2–960.2 MHz; 41.8 mW/cm^2). The study reported increases in the amplitude of evoked spindles by about 87% (mobile phone), 17% (2% KCl), and 226% (mobile phone & 2% KCl) compared with control, and suggested evoked spindle amplitude was a sensitive indicator of EMF exposure effects.",
    "effect_direction": "harm",
    "limitations": [
        "Sample size not reported in the abstract",
        "Exposure duration not reported in the abstract",
        "No SAR reported in the abstract",
        "Details of control conditions and statistical testing are not provided in the abstract"
    ],
    "evidence_strength": "low",
    "confidence": 0.7399999999999999911182158029987476766109466552734375,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "mouse",
        "EEG",
        "cortical spreading depression",
        "mobile phone",
        "RF EMF",
        "935.2-960.2 MHz",
        "spindle activity",
        "slow potential changes"
    ],
    "suggested_hubs": [
        {
            "slug": "mobile-phones-rf",
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            "reason": "Exposure source is a mobile phone emitting RF EMFs; EEG outcomes assessed in mice."
        }
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}

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