Enhancement of allergic skin wheal responses by microwave radiation from mobile phones in patients with atopic eczema/dermatitis syndrome.

PAPER pubmed International archives of allergy and immunology 2002 Unknown Effect: mixed Evidence: Insufficient

Read original paper → DOI: 10.1159/000067592 PMID: 12483040 Evidence Lab

Abstract

Microwave radiation from mobile phones enhanced skin wheal responses induced by house dust mite and Japanese cedar pollen while it had no effect on wheal responses induced by histamine in patients with atopic eczema/dermatitis syndrome (AEDS). Microwave radiation also increased plasma levels of substance P (SP) and vasoactive intestinal peptide (VIP) in patients with AEDS. These results indicate that microwave radiation from mobile phones may enhance allergen-induced wheal responses in association with the release of SP and VIP. This finding may be useful in elucidating the pathophysiology and treatment of AEDS.

AI evidence extraction

At a glance

Study type

Unknown

Effect direction

mixed

Population

Patients with atopic eczema/dermatitis syndrome (AEDS)

Sample size

—

Exposure

microwave mobile phone

Evidence strength

Insufficient

Confidence: 66% · Peer-reviewed: yes

Main findings

Microwave radiation from mobile phones enhanced allergen-induced skin wheal responses (house dust mite and Japanese cedar pollen) but had no effect on histamine-induced wheal responses in patients with AEDS. Microwave radiation also increased plasma levels of substance P and vasoactive intestinal peptide in these patients.

Outcomes measured

Skin wheal responses induced by house dust mite
Skin wheal responses induced by Japanese cedar pollen
Skin wheal responses induced by histamine
Plasma substance P (SP) levels
Plasma vasoactive intestinal peptide (VIP) levels

Limitations

Study design not described in abstract
Sample size not reported
Exposure parameters (frequency, SAR, duration) not reported

Suggested hubs

mobile-phones-rf (0.9)
Examines microwave radiation from mobile phones and biological/clinical responses.

View raw extracted JSON

{
    "study_type": "unknown",
    "exposure": {
        "band": "microwave",
        "source": "mobile phone",
        "frequency_mhz": null,
        "sar_wkg": null,
        "duration": null
    },
    "population": "Patients with atopic eczema/dermatitis syndrome (AEDS)",
    "sample_size": null,
    "outcomes": [
        "Skin wheal responses induced by house dust mite",
        "Skin wheal responses induced by Japanese cedar pollen",
        "Skin wheal responses induced by histamine",
        "Plasma substance P (SP) levels",
        "Plasma vasoactive intestinal peptide (VIP) levels"
    ],
    "main_findings": "Microwave radiation from mobile phones enhanced allergen-induced skin wheal responses (house dust mite and Japanese cedar pollen) but had no effect on histamine-induced wheal responses in patients with AEDS. Microwave radiation also increased plasma levels of substance P and vasoactive intestinal peptide in these patients.",
    "effect_direction": "mixed",
    "limitations": [
        "Study design not described in abstract",
        "Sample size not reported",
        "Exposure parameters (frequency, SAR, duration) not reported"
    ],
    "evidence_strength": "insufficient",
    "confidence": 0.66000000000000003108624468950438313186168670654296875,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "microwave radiation",
        "mobile phone",
        "atopic eczema/dermatitis syndrome",
        "AEDS",
        "skin wheal response",
        "house dust mite",
        "Japanese cedar pollen",
        "histamine",
        "substance P",
        "vasoactive intestinal peptide",
        "VIP"
    ],
    "suggested_hubs": [
        {
            "slug": "mobile-phones-rf",
            "weight": 0.90000000000000002220446049250313080847263336181640625,
            "reason": "Examines microwave radiation from mobile phones and biological/clinical responses."
        }
    ]
}

AI can be wrong. Always verify against the paper.

AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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