[Changes in serum alkaline phosphatase activity during in vitro exposure to amplitude-modulated electromagnetic field of ultrahigh frequency (2375 MHz) in guinea pigs].

PAPER pubmed Biofizika 2000 Animal study Effect: harm Evidence: Low

Read original paper → PMID: 10732222 Evidence Lab

Abstract

The activity of alkaline phosphatase by the action of pulse-modulated microwave radiation was studied. The carrier frequency of radiation was 2375 MHz, the range of modulation pulse rate was 10-390 Hz with the on-off time ratio 2, and the specific absorption rate was 8 and 0.8 microW/cm2. Time of exposure was 1 and 3 min under conditions of continuous temperature control. It was shown that the activity of alkaline phosphatase depends on both modulation frequency and intensity of superhigh-frequency electromagnetic radiation. At a frequency of 70 Hz, the activity of alkaline phosphatases increased 1.8-2.0 times.

AI evidence extraction

At a glance

Study type

Animal study

Effect direction

harm

Population

guinea pigs (in vitro serum)

Sample size

—

Exposure

RF · 2375 MHz · 1 and 3 min

Evidence strength

Low

Confidence: 74% · Peer-reviewed: yes

Main findings

In vitro exposure to pulse-modulated microwave radiation (carrier 2375 MHz; modulation pulse rate 10–390 Hz) altered alkaline phosphatase activity depending on modulation frequency and intensity. At 70 Hz modulation, alkaline phosphatase activity increased by about 1.8–2.0 times.

Outcomes measured

serum alkaline phosphatase activity

Limitations

In vitro study (serum enzyme activity) rather than whole-animal health outcomes
Sample size not reported in abstract
Exposure metric reported as microW/cm2; SAR in W/kg not provided
Short exposure durations (1 and 3 minutes)

View raw extracted JSON

{
    "study_type": "animal",
    "exposure": {
        "band": "RF",
        "source": null,
        "frequency_mhz": 2375,
        "sar_wkg": null,
        "duration": "1 and 3 min"
    },
    "population": "guinea pigs (in vitro serum)",
    "sample_size": null,
    "outcomes": [
        "serum alkaline phosphatase activity"
    ],
    "main_findings": "In vitro exposure to pulse-modulated microwave radiation (carrier 2375 MHz; modulation pulse rate 10–390 Hz) altered alkaline phosphatase activity depending on modulation frequency and intensity. At 70 Hz modulation, alkaline phosphatase activity increased by about 1.8–2.0 times.",
    "effect_direction": "harm",
    "limitations": [
        "In vitro study (serum enzyme activity) rather than whole-animal health outcomes",
        "Sample size not reported in abstract",
        "Exposure metric reported as microW/cm2; SAR in W/kg not provided",
        "Short exposure durations (1 and 3 minutes)"
    ],
    "evidence_strength": "low",
    "confidence": 0.7399999999999999911182158029987476766109466552734375,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "2375 MHz",
        "microwave",
        "RF",
        "pulse-modulated",
        "amplitude-modulated",
        "modulation frequency",
        "guinea pig",
        "in vitro",
        "alkaline phosphatase",
        "enzyme activity"
    ],
    "suggested_hubs": []
}

AI can be wrong. Always verify against the paper.

AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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