[Synaptic transmission in the frog spinal cord exposed to intensive microwave radiation].

PAPER pubmed Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova 1991 Animal study Effect: no_effect Evidence: Low

Read original paper → PMID: 1652496 Evidence Lab

Abstract

Microwave (6.45 GHz, CW, SAR 0.1-2 W/g) effects on mono- and polysynaptic transmission, temporal and spatial EPSP summation were investigated in isolated frog spinal cord. No changes were observed if the preparation temperature remained constant during irradiation. VHF and conventional heating produced the same effects. The data obtained confirm the thermal mechanism of VHF influences on synaptic transmission processes.

AI evidence extraction

At a glance

Study type

Animal study

Effect direction

no_effect

Population

Isolated frog spinal cord

Sample size

—

Exposure

microwave · 6450 MHz

Evidence strength

Low

Confidence: 74% · Peer-reviewed: yes

Main findings

In isolated frog spinal cord exposed to continuous-wave 6.45 GHz microwaves (SAR 0.1–2 W/g), no changes in synaptic transmission or EPSP summation were observed when preparation temperature was kept constant. VHF and conventional heating produced the same effects, supporting a thermal mechanism.

Outcomes measured

Monosynaptic transmission
Polysynaptic transmission
Temporal EPSP summation
Spatial EPSP summation

Limitations

Sample size not reported in abstract
Exposure duration not reported in abstract
Details of experimental methods and controls not provided in abstract

View raw extracted JSON

{
    "study_type": "animal",
    "exposure": {
        "band": "microwave",
        "source": null,
        "frequency_mhz": 6450,
        "sar_wkg": null,
        "duration": null
    },
    "population": "Isolated frog spinal cord",
    "sample_size": null,
    "outcomes": [
        "Monosynaptic transmission",
        "Polysynaptic transmission",
        "Temporal EPSP summation",
        "Spatial EPSP summation"
    ],
    "main_findings": "In isolated frog spinal cord exposed to continuous-wave 6.45 GHz microwaves (SAR 0.1–2 W/g), no changes in synaptic transmission or EPSP summation were observed when preparation temperature was kept constant. VHF and conventional heating produced the same effects, supporting a thermal mechanism.",
    "effect_direction": "no_effect",
    "limitations": [
        "Sample size not reported in abstract",
        "Exposure duration not reported in abstract",
        "Details of experimental methods and controls not provided in abstract"
    ],
    "evidence_strength": "low",
    "confidence": 0.7399999999999999911182158029987476766109466552734375,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "microwave",
        "6.45 GHz",
        "continuous wave",
        "SAR",
        "frog",
        "spinal cord",
        "synaptic transmission",
        "EPSP summation",
        "thermal mechanism",
        "heating"
    ],
    "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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