B16 melanoma development in black mice exposed to low-level microwave radiation.

PAPER pubmed Bioelectromagnetics 1988 Animal study Effect: no_effect Evidence: Low

Read original paper → DOI: 10.1002/bem.2250090110 PMID: 3345211 Evidence Lab

Abstract

The effect of low-level microwave exposure, 2,450 MHz, at a power density of 1 mW/cm2 and specific absorption rate of 1.2 mW/g, continuous waves (CW) or pulsed waves (PW), 2.5 h/day, 6 sessions/week until death (up to 690 h of irradiation), has been studied in black C57/6J mice with B16 melanoma. The results show that no significant effects are observed on tumor development or on survival times compared to controls, or between CW- and PW-treated animals.

AI evidence extraction

At a glance

Study type

Animal study

Effect direction

no_effect

Population

Black C57/6J mice with B16 melanoma

Sample size

—

Exposure

microwave · 2450 MHz · 0.0012 W/kg · 2.5 h/day, 6 sessions/week until death (up to 690 h)

Evidence strength

Low

Confidence: 78% · Peer-reviewed: yes

Main findings

In black C57/6J mice with B16 melanoma, low-level 2,450 MHz microwave exposure (1 mW/cm2; SAR 1.2 mW/g) for up to 690 hours showed no significant effects on tumor development or survival compared with controls. No significant differences were observed between continuous-wave and pulsed-wave exposure.

Outcomes measured

tumor development
survival time

Limitations

Sample size not reported in the provided abstract/metadata.
Details of randomization/blinding and tumor assessment methods not reported in the provided abstract/metadata.

View raw extracted JSON

{
    "study_type": "animal",
    "exposure": {
        "band": "microwave",
        "source": null,
        "frequency_mhz": 2450,
        "sar_wkg": 0.00119999999999999989487575735580549007863737642765045166015625,
        "duration": "2.5 h/day, 6 sessions/week until death (up to 690 h)"
    },
    "population": "Black C57/6J mice with B16 melanoma",
    "sample_size": null,
    "outcomes": [
        "tumor development",
        "survival time"
    ],
    "main_findings": "In black C57/6J mice with B16 melanoma, low-level 2,450 MHz microwave exposure (1 mW/cm2; SAR 1.2 mW/g) for up to 690 hours showed no significant effects on tumor development or survival compared with controls. No significant differences were observed between continuous-wave and pulsed-wave exposure.",
    "effect_direction": "no_effect",
    "limitations": [
        "Sample size not reported in the provided abstract/metadata.",
        "Details of randomization/blinding and tumor assessment methods not reported in the provided abstract/metadata."
    ],
    "evidence_strength": "low",
    "confidence": 0.7800000000000000266453525910037569701671600341796875,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "microwave radiation",
        "2450 MHz",
        "power density",
        "specific absorption rate",
        "continuous wave",
        "pulsed wave",
        "C57/6J mice",
        "B16 melanoma",
        "tumor development",
        "survival"
    ],
    "suggested_hubs": []
}

AI can be wrong. Always verify against the paper.

AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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