Microwave effect on camphor binding to rat olfactory epithelium.

PAPER pubmed Bioelectromagnetics 1988 Animal study Effect: harm Evidence: Low

Read original paper → DOI: 10.1002/bem.2250090404 PMID: 3190762 Evidence Lab

Abstract

Microwave radiation decreased specific camphor binding to a membrane fraction of rat epithelium but not to a Triton X-100 extract of this fraction. Inhibition of the ligand binding did not depend on the modulation frequency of the microwave field in the region 1-100 Hz and was not a linear function of specific absorption rate (SAR). The decreased ligand binding was due to a shedding or release of the specific camphor-binding protein from the membrane into solution. It is highly probable that several other membrane proteins may be shed into solution during microwave exposure.

AI evidence extraction

At a glance

Study type

Animal study

Effect direction

harm

Population

Rat olfactory epithelium (membrane fraction/extract)

Sample size

—

Exposure

microwave

Evidence strength

Low

Confidence: 74% · Peer-reviewed: yes

Main findings

Microwave radiation decreased specific camphor binding to a membrane fraction of rat olfactory epithelium, but not to a Triton X-100 extract of the fraction. The inhibition did not depend on modulation frequency (1–100 Hz) and was not a linear function of SAR. The decrease in binding was attributed to shedding/release of the specific camphor-binding protein from the membrane into solution.

Outcomes measured

Specific camphor binding to membrane fraction
Camphor binding to Triton X-100 extract
Shedding/release of camphor-binding protein from membrane into solution

Limitations

Sample size not reported in abstract
Microwave carrier frequency and exposure duration not reported in abstract
Outcome is a biochemical binding measure; broader physiological/health relevance not assessed in abstract
SAR-response described as non-linear but quantitative SAR levels not provided in abstract

View raw extracted JSON

{
    "study_type": "animal",
    "exposure": {
        "band": "microwave",
        "source": null,
        "frequency_mhz": null,
        "sar_wkg": null,
        "duration": null
    },
    "population": "Rat olfactory epithelium (membrane fraction/extract)",
    "sample_size": null,
    "outcomes": [
        "Specific camphor binding to membrane fraction",
        "Camphor binding to Triton X-100 extract",
        "Shedding/release of camphor-binding protein from membrane into solution"
    ],
    "main_findings": "Microwave radiation decreased specific camphor binding to a membrane fraction of rat olfactory epithelium, but not to a Triton X-100 extract of the fraction. The inhibition did not depend on modulation frequency (1–100 Hz) and was not a linear function of SAR. The decrease in binding was attributed to shedding/release of the specific camphor-binding protein from the membrane into solution.",
    "effect_direction": "harm",
    "limitations": [
        "Sample size not reported in abstract",
        "Microwave carrier frequency and exposure duration not reported in abstract",
        "Outcome is a biochemical binding measure; broader physiological/health relevance not assessed in abstract",
        "SAR-response described as non-linear but quantitative SAR levels not provided in abstract"
    ],
    "evidence_strength": "low",
    "confidence": 0.7399999999999999911182158029987476766109466552734375,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "microwave radiation",
        "rat",
        "olfactory epithelium",
        "camphor binding",
        "membrane proteins",
        "protein shedding",
        "modulation frequency",
        "SAR"
    ],
    "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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