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Ultrastructural changes in the rabbit lens induced by microwave radiation.

PAPER pubmed Annals of the New York Academy of Sciences 1975 Animal study Effect: harm Evidence: Very low

Abstract

Rabbits were irradiated with 2450-MHz continuous microwave energy. Effects of the radiation on the ocular lens were assessed by slit-lamp biomicroscopic examination of the eye. Two lenses were selected for electron microscopy, one that was severely damaged and one that appeared unaffected by the radiation. There were prominent ultrastructural changes in both lenses.

AI evidence extraction

At a glance
Study type
Animal study
Effect direction
harm
Population
Rabbits
Sample size
Exposure
microwave · 2450 MHz
Evidence strength
Very low
Confidence: 66% · Peer-reviewed: yes

Main findings

Rabbits were exposed to 2450-MHz continuous microwave radiation and lens effects were assessed by slit-lamp examination. Electron microscopy of two selected lenses (one severely damaged by slit-lamp exam and one appearing unaffected) found prominent ultrastructural changes in both lenses.

Outcomes measured

  • Ocular lens damage
  • Ultrastructural (electron microscopy) changes in the lens

Limitations

  • Sample size not reported in abstract
  • Only two lenses were selected for electron microscopy
  • Exposure metrics beyond frequency (e.g., power density/SAR, duration) not reported in abstract
  • Selection of lenses for electron microscopy may introduce selection bias
View raw extracted JSON
{
    "study_type": "animal",
    "exposure": {
        "band": "microwave",
        "source": null,
        "frequency_mhz": 2450,
        "sar_wkg": null,
        "duration": null
    },
    "population": "Rabbits",
    "sample_size": null,
    "outcomes": [
        "Ocular lens damage",
        "Ultrastructural (electron microscopy) changes in the lens"
    ],
    "main_findings": "Rabbits were exposed to 2450-MHz continuous microwave radiation and lens effects were assessed by slit-lamp examination. Electron microscopy of two selected lenses (one severely damaged by slit-lamp exam and one appearing unaffected) found prominent ultrastructural changes in both lenses.",
    "effect_direction": "harm",
    "limitations": [
        "Sample size not reported in abstract",
        "Only two lenses were selected for electron microscopy",
        "Exposure metrics beyond frequency (e.g., power density/SAR, duration) not reported in abstract",
        "Selection of lenses for electron microscopy may introduce selection bias"
    ],
    "evidence_strength": "very_low",
    "confidence": 0.66000000000000003108624468950438313186168670654296875,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "rabbit",
        "microwave radiation",
        "2450 MHz",
        "ocular lens",
        "slit-lamp biomicroscopy",
        "electron microscopy",
        "ultrastructural changes"
    ],
    "suggested_hubs": []
}

AI can be wrong. Always verify against the paper.

AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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