Measure of enzymatic activity coincident with 2450 MHz microwave exposure.

PAPER pubmed The Journal of microwave power 1975 In vitro study Effect: no_effect Evidence: Low

Read original paper → DOI: 10.1080/00222739.1975.11688968 PMID: 175163 Evidence Lab

Abstract

Enzyme preparations were exposed to microwave radiation at 2450 MHz and enzymatic activity was simultaneously monitored spectrophotometrically with a crossed-beam exposure detection system. Enzymes studied were glucose 6-phosphate dehydrogenase from human red blood cells and yeast, adenylate kinase from rat liver mitochondria and rabbit muscle, and rat liver microsomal NADPH cytochrome c reductase. No difference was found between the specific activity at 25 degrees C of unirradiated controls and enzyme preparations irradiated at an absorbed dose rate of 42 W/kg.

AI evidence extraction

At a glance

Study type

In vitro study

Effect direction

no_effect

Population

—

Sample size

—

Exposure

microwave · 2450 MHz · 42 W/kg

Evidence strength

Low

Confidence: 78% · Peer-reviewed: yes

Main findings

Enzyme preparations exposed to 2450 MHz microwaves at an absorbed dose rate of 42 W/kg showed no difference in specific activity at 25°C compared with unirradiated controls.

Outcomes measured

Enzymatic activity (specific activity) of glucose 6-phosphate dehydrogenase (human red blood cells and yeast)
Enzymatic activity (specific activity) of adenylate kinase (rat liver mitochondria and rabbit muscle)
Enzymatic activity (specific activity) of rat liver microsomal NADPH cytochrome c reductase

Limitations

Exposure duration not reported in abstract
Sample size/number of replicates not reported in abstract
Only one temperature condition (25°C) mentioned in abstract
In vitro enzyme preparations; findings may not generalize beyond the tested preparations and conditions

View raw extracted JSON

{
    "study_type": "in_vitro",
    "exposure": {
        "band": "microwave",
        "source": null,
        "frequency_mhz": 2450,
        "sar_wkg": 42,
        "duration": null
    },
    "population": null,
    "sample_size": null,
    "outcomes": [
        "Enzymatic activity (specific activity) of glucose 6-phosphate dehydrogenase (human red blood cells and yeast)",
        "Enzymatic activity (specific activity) of adenylate kinase (rat liver mitochondria and rabbit muscle)",
        "Enzymatic activity (specific activity) of rat liver microsomal NADPH cytochrome c reductase"
    ],
    "main_findings": "Enzyme preparations exposed to 2450 MHz microwaves at an absorbed dose rate of 42 W/kg showed no difference in specific activity at 25°C compared with unirradiated controls.",
    "effect_direction": "no_effect",
    "limitations": [
        "Exposure duration not reported in abstract",
        "Sample size/number of replicates not reported in abstract",
        "Only one temperature condition (25°C) mentioned in abstract",
        "In vitro enzyme preparations; findings may not generalize beyond the tested preparations and conditions"
    ],
    "evidence_strength": "low",
    "confidence": 0.7800000000000000266453525910037569701671600341796875,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "2450 MHz",
        "microwave radiation",
        "enzyme activity",
        "spectrophotometry",
        "crossed-beam exposure detection system",
        "glucose 6-phosphate dehydrogenase",
        "adenylate kinase",
        "NADPH cytochrome c reductase",
        "absorbed dose rate",
        "42 W/kg"
    ],
    "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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