A system for studying effects of microwaves on cells in culture.

PAPER pubmed The Journal of microwave power 1978 Engineering / measurement Effect: harm Evidence: Low

Read original paper → DOI: 10.1080/16070658.1978.11689102 PMID: 255162 Evidence Lab

Abstract

An improved design of the fluid-filled waveguide-exposure chamber is described for studying effects of microwave radiation on cells in vitro. The system with a micropipette sample holder may be used as a prototype to isolate the apparent nonthermal factor of microwave radiation on cells in culture from those effects resulting from cell temperature rise. This system also allows more precise calibration of incident and absorbed microwave energies. Compared with control, somatic cells of the Chinese hamster exhibited a lower rate of growth and difference in morphology after 2450 MHz microwave radiation for 20 min at a power density of 500 mW/cm2.

AI evidence extraction

At a glance

Study type

Engineering / measurement

Effect direction

harm

Population

Somatic cells of the Chinese hamster (in vitro cell culture)

Sample size

—

Exposure

microwave · 2450 MHz · 20 min

Evidence strength

Low

Confidence: 66% · Peer-reviewed: yes

Main findings

The paper describes an improved fluid-filled waveguide exposure chamber with a micropipette sample holder intended to help separate apparent nonthermal microwave effects from effects due to temperature rise and to allow more precise calibration of incident and absorbed energies. Compared with control, Chinese hamster somatic cells showed a lower growth rate and differences in morphology after 2450 MHz exposure for 20 minutes at 500 mW/cm2.

Outcomes measured

cell growth rate
cell morphology
incident and absorbed microwave energy calibration
temperature rise/nonthermal factor isolation

Limitations

Sample size not reported in abstract
No quantitative results or statistical details reported in abstract
Specific temperature control/measurement details not provided in abstract

View raw extracted JSON

{
    "study_type": "engineering",
    "exposure": {
        "band": "microwave",
        "source": null,
        "frequency_mhz": 2450,
        "sar_wkg": null,
        "duration": "20 min"
    },
    "population": "Somatic cells of the Chinese hamster (in vitro cell culture)",
    "sample_size": null,
    "outcomes": [
        "cell growth rate",
        "cell morphology",
        "incident and absorbed microwave energy calibration",
        "temperature rise/nonthermal factor isolation"
    ],
    "main_findings": "The paper describes an improved fluid-filled waveguide exposure chamber with a micropipette sample holder intended to help separate apparent nonthermal microwave effects from effects due to temperature rise and to allow more precise calibration of incident and absorbed energies. Compared with control, Chinese hamster somatic cells showed a lower growth rate and differences in morphology after 2450 MHz exposure for 20 minutes at 500 mW/cm2.",
    "effect_direction": "harm",
    "limitations": [
        "Sample size not reported in abstract",
        "No quantitative results or statistical details reported in abstract",
        "Specific temperature control/measurement details not provided in abstract"
    ],
    "evidence_strength": "low",
    "confidence": 0.66000000000000003108624468950438313186168670654296875,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "microwave radiation",
        "in vitro",
        "cell culture",
        "waveguide exposure chamber",
        "fluid-filled waveguide",
        "micropipette sample holder",
        "nonthermal effects",
        "temperature rise",
        "2450 MHz",
        "power density 500 mW/cm2",
        "Chinese hamster cells"
    ],
    "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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