Effects of pulsed magnetic fields in the therapy of osteoporosis induced by ovariectomy in the rat.

PAPER pubmed Bollettino della Societa italiana di biologia sperimentale 1993 Animal study Effect: benefit Evidence: Low

Read original paper → PMID: 8155304 Evidence Lab

Abstract

This paper presents preliminary results on the effects of pulsed electromagnetic fields (EMF) in the therapy of post menopausal osteoporosis induced by ovariectomy in female rats aged ten months. In particular, the effects of the intensity of pulsed EMF applied at constant frequency has been studied. Magnetic fields pulsed at 50 Hz were used having a positive sinusoidal wave form with a maximum intensity of 30 and 70 Gauss. Treatment lasting one hour per day for 4 months showed that the pulsed EMF with 30 Gauss of maximum intensity are able to slow down the bone mass loss, keeping it within some 10%; with pulsed EMF with 70 Gauss of maximum intensity, instead, no significant bone mass loss was observed.

AI evidence extraction

At a glance

Study type

Animal study

Effect direction

benefit

Population

Female rats aged ten months with post-menopausal osteoporosis induced by ovariectomy

Sample size

—

Exposure

ELF therapeutic pulsed electromagnetic fields · 0.05 MHz · 1 hour/day for 4 months

Evidence strength

Low

Confidence: 74% · Peer-reviewed: yes

Main findings

In ovariectomized female rats treated 1 hour/day for 4 months with 50 Hz pulsed magnetic fields, 30 Gauss maximum intensity slowed bone mass loss to within about 10%. With 70 Gauss maximum intensity, no significant bone mass loss was observed.

Outcomes measured

Bone mass loss (bone mass)

Limitations

Preliminary results
Sample size not reported in abstract
Details of study design and outcome measurement methods not reported in abstract

View raw extracted JSON

{
    "study_type": "animal",
    "exposure": {
        "band": "ELF",
        "source": "therapeutic pulsed electromagnetic fields",
        "frequency_mhz": 0.05000000000000000277555756156289135105907917022705078125,
        "sar_wkg": null,
        "duration": "1 hour/day for 4 months"
    },
    "population": "Female rats aged ten months with post-menopausal osteoporosis induced by ovariectomy",
    "sample_size": null,
    "outcomes": [
        "Bone mass loss (bone mass)"
    ],
    "main_findings": "In ovariectomized female rats treated 1 hour/day for 4 months with 50 Hz pulsed magnetic fields, 30 Gauss maximum intensity slowed bone mass loss to within about 10%. With 70 Gauss maximum intensity, no significant bone mass loss was observed.",
    "effect_direction": "benefit",
    "limitations": [
        "Preliminary results",
        "Sample size not reported in abstract",
        "Details of study design and outcome measurement methods not reported in abstract"
    ],
    "evidence_strength": "low",
    "confidence": 0.7399999999999999911182158029987476766109466552734375,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "pulsed electromagnetic fields",
        "pulsed magnetic fields",
        "50 Hz",
        "30 Gauss",
        "70 Gauss",
        "osteoporosis",
        "ovariectomy",
        "rat",
        "bone mass"
    ],
    "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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