Iron deposition in rabbit cerebellum after exposure to generated and mobile GSM electromagnetic fields.
Abstract
BACKGROUND: Mobile phone application may cause structural, functional changes and accumulation of toxic elements in brain. OBJECTIVES: The aim of this study was to investigate iron accumulation in rabbit cerebellum after exposure to RF EMF with light and scanning electron microscopy. MATERIALS AND METHODS: Histochemical analysis of iron distribution by light and electron microscopy with energy-dispersive microanalysis was used. RESULTS: Light microscopy revealed dystrophic changes of Purkinje cells in irradiated groups and iron deposits located in various parts of cerebellum. Deposits consists of C, O, Na, Mg, Al, Si, P, S, Cl, Ca and Fe. CONCLUSION: Our experiment revealed structural changes of Purkinje cells and iron and aluminium accumulations in stratum granulosum of rabbit's cerebellum after exposure to RF EMF (Fig. 6, Ref. 33).
AI evidence extraction
Main findings
In irradiated rabbit groups, light microscopy showed dystrophic changes of Purkinje cells and deposits in various parts of the cerebellum. The authors report iron and aluminium accumulations in the stratum granulosum after RF EMF exposure; deposits contained multiple elements including Fe.
Outcomes measured
- Iron accumulation/deposition in cerebellum
- Aluminium accumulation in cerebellum
- Structural changes of Purkinje cells (dystrophic changes)
- Elemental composition of deposits (EDS microanalysis)
Limitations
- Exposure parameters (e.g., frequency, SAR, duration) not reported in the abstract
- Sample size not reported in the abstract
- Details of control/sham conditions not described in the abstract
Suggested hubs
-
rf-mobile-phones
(0.9) Study examines GSM/mobile-phone RF EMF exposure and brain tissue outcomes in an animal model.
View raw extracted JSON
{
"study_type": "animal",
"exposure": {
"band": "RF",
"source": "mobile phone",
"frequency_mhz": null,
"sar_wkg": null,
"duration": null
},
"population": "Rabbits",
"sample_size": null,
"outcomes": [
"Iron accumulation/deposition in cerebellum",
"Aluminium accumulation in cerebellum",
"Structural changes of Purkinje cells (dystrophic changes)",
"Elemental composition of deposits (EDS microanalysis)"
],
"main_findings": "In irradiated rabbit groups, light microscopy showed dystrophic changes of Purkinje cells and deposits in various parts of the cerebellum. The authors report iron and aluminium accumulations in the stratum granulosum after RF EMF exposure; deposits contained multiple elements including Fe.",
"effect_direction": "harm",
"limitations": [
"Exposure parameters (e.g., frequency, SAR, duration) not reported in the abstract",
"Sample size not reported in the abstract",
"Details of control/sham conditions not described in the abstract"
],
"evidence_strength": "low",
"confidence": 0.66000000000000003108624468950438313186168670654296875,
"peer_reviewed_likely": "yes",
"keywords": [
"rabbit",
"cerebellum",
"Purkinje cells",
"iron deposition",
"aluminium accumulation",
"RF EMF",
"GSM",
"mobile phone",
"light microscopy",
"scanning electron microscopy",
"energy-dispersive microanalysis"
],
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{
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"weight": 0.90000000000000002220446049250313080847263336181640625,
"reason": "Study examines GSM/mobile-phone RF EMF exposure and brain tissue outcomes in an animal model."
}
]
}
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