The impact of electromagnetic radiation of different parameters on platelet oxygen metabolism - in vitro studies.

PAPER pubmed Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2015 In vitro study Effect: harm Evidence: Low

Read original paper → DOI: 10.17219/acem/38169 PMID: 25923084 Evidence Lab

Abstract

BACKGROUND: Electromagnetic radiation emitted by a variety of devices, e.g. cell phones, computers and microwaves, interacts with the human body in many ways. Research studies carried out in the last few decades have not yet resolved the issue of the effect of this factor on the human body and many questions are left without an unequivocal answer. Various biological and health-related effects have not been fully recognized. Thus further studies in this area are justified. OBJECTIVES: A comparison of changes within catalase enzymatic activity and malondialdehyde concentration arising under the influence of the electromagnetic radiation emitted by car electronics, equipment used in physiotherapy and LCD monitors. MATERIAL AND METHODS: The suspension of human blood platelets at a concentration of 1 × 109/0.001 dm 3, obtained from whole blood by manual apheresis, was the study material. Blood platelets were exposed to an electromagnetic field for 30 min in a laboratory stand designed for the reconstruction of the electromagnetic radiation generated by car electronics, physiotherapy equipment and LCD monitors. The changes in catalase activity and malondialdehyde concentration were investigated after the exposure and compared to the control values (unexposed material). RESULTS: An increase in catalase activity and malondialdehyde concentration was observed after 30 min exposure of platelets to EMF regardless of the radiation source. The most significant changes determining the degree of oxidative stress were observed after exposure to the EMF generated by car electronics. CONCLUSIONS: The low frequency electromagnetic fields generated by car electronics, physiotherapy equipment and LCD monitors may be a cause of oxidative stress in the human body and may lead to free radical diseases.

AI evidence extraction

At a glance

Study type

In vitro study

Effect direction

harm

Population

Human blood platelets (suspension) obtained from whole blood by manual apheresis

Sample size

—

Exposure

ELF car electronics; physiotherapy equipment; LCD monitors · 30 min

Evidence strength

Low

Confidence: 78% · Peer-reviewed: yes

Main findings

After 30 minutes of exposure, catalase activity and malondialdehyde concentration increased versus unexposed controls for all EMF sources tested. The largest changes were reported after exposure to EMF generated by car electronics.

Outcomes measured

Catalase enzymatic activity
Malondialdehyde (MDA) concentration
Oxidative stress (biomarker changes)

Limitations

In vitro platelet suspension model; may not reflect whole-body or in vivo effects
Exposure parameters (e.g., field strength, exact frequency characteristics) not reported in the abstract
Sample size not reported in the abstract
Only short-term (30 min) exposure assessed
Limited set of oxidative stress-related biomarkers assessed

Suggested hubs

occupational-exposure (0.35)
Includes exposure source described as physiotherapy equipment (workplace-related EMF possible), though context is laboratory reconstruction rather than field measurements.

View raw extracted JSON

{
    "study_type": "in_vitro",
    "exposure": {
        "band": "ELF",
        "source": "car electronics; physiotherapy equipment; LCD monitors",
        "frequency_mhz": null,
        "sar_wkg": null,
        "duration": "30 min"
    },
    "population": "Human blood platelets (suspension) obtained from whole blood by manual apheresis",
    "sample_size": null,
    "outcomes": [
        "Catalase enzymatic activity",
        "Malondialdehyde (MDA) concentration",
        "Oxidative stress (biomarker changes)"
    ],
    "main_findings": "After 30 minutes of exposure, catalase activity and malondialdehyde concentration increased versus unexposed controls for all EMF sources tested. The largest changes were reported after exposure to EMF generated by car electronics.",
    "effect_direction": "harm",
    "limitations": [
        "In vitro platelet suspension model; may not reflect whole-body or in vivo effects",
        "Exposure parameters (e.g., field strength, exact frequency characteristics) not reported in the abstract",
        "Sample size not reported in the abstract",
        "Only short-term (30 min) exposure assessed",
        "Limited set of oxidative stress-related biomarkers assessed"
    ],
    "evidence_strength": "low",
    "confidence": 0.7800000000000000266453525910037569701671600341796875,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "electromagnetic field",
        "low frequency",
        "platelets",
        "catalase",
        "malondialdehyde",
        "oxidative stress",
        "car electronics",
        "physiotherapy equipment",
        "LCD monitor"
    ],
    "suggested_hubs": [
        {
            "slug": "occupational-exposure",
            "weight": 0.34999999999999997779553950749686919152736663818359375,
            "reason": "Includes exposure source described as physiotherapy equipment (workplace-related EMF possible), though context is laboratory reconstruction rather than field measurements."
        }
    ]
}

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AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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