Panax ginseng supplementation protects against testicular damage induced by radiofrequency electromagnetic radiation from cell phone
Abstract
Panax ginseng supplementation protects against testicular damage induced by radiofrequency electromagnetic radiation from cell phone Oyewopo AO, Badejogbin OC, Ajadi IO et al. Panax ginseng supplementation protects against testicular damage induced by radiofrequency electromagnetic radiation from cell phone. Nutrire 48, 47 (2023). doi.org Abstract Purpose It is well-documented that radiofrequency electromagnetic radiation (RF-EMR) from the cell phone contributes to testicular dysfunction and subsequently predisposes individuals, especially male to infertility. Panax ginseng (P. ginseng) exerts antioxidant, antidiabetic, neuroprotective, and anti-inflammatory effects in biological systems. However, its protective role against reproductive dysfunction, including testiculopathy is unclear. The objective of this study was to examine the protective effects of P. ginseng extract on testicular damage induced by RF-EMR from cell phones in male Wistar rats. Methods Twenty adult male Wistar rats (120–150 g) were randomly divided into four groups of n = 5; Control group received vehicle (normal saline, po), P. ginseng group received 200 mg/kg of P. ginseng extract (po), RF- EMR group was exposed to 900MHz of radiation and RF-EMR + P. ginseng group was exposed to 900MHz of radiation and was concomitantly treated with 200 mg/kg of P. ginseng (po). The treatment was done daily for 56 days. The animals were sacrificed, and the biochemical/endocrine parameters and the histology of testes were evaluated. Results There was a significant decrease in spermatogonia, sperm count, sperm motility, and sperm morphology with decrease in progressivity in RF-EMR group compared with control. Likewise, a significant decrease was observed in serum-luteinizing hormone, testosterone and glutathione peroxidase with degeneration of germ cells and Leydig cells, and a distorted interstitium in RF-EMR group compared with control. However, the administration of P. ginseng attenuated these alterations. Conclusion The results of the present study suggest that supplementation with P. ginseng extract ameliorates testicular dysfunction associated with RF-EMR from cell phone by enhancement of antioxidant capacity. link.springer.com
AI evidence extraction
Main findings
In rats exposed to 900 MHz RF-EMR, the study reports decreases in spermatogonia, sperm count, motility, morphology, and progressivity, along with reduced serum luteinizing hormone, testosterone, and glutathione peroxidase and histologic degeneration compared with controls. Concomitant Panax ginseng (200 mg/kg) administration reportedly attenuated these RF-EMR-associated alterations.
Outcomes measured
- Spermatogonia (count/levels)
- Sperm count
- Sperm motility
- Sperm morphology
- Sperm progressivity
- Serum luteinizing hormone
- Serum testosterone
- Glutathione peroxidase
- Testicular histology (germ cells, Leydig cells, interstitium)
Limitations
- Animal study; findings may not generalize to humans.
- Small group sizes (n=5 per group).
- Specific exposure details beyond frequency (e.g., SAR, field strength, distance, device model) are not provided in the abstract.
- The abstract does not describe blinding or randomization procedures beyond group assignment.
Suggested hubs
-
cell-phones
(0.95) Study explicitly examines RF-EMR described as from cell phones and reproductive outcomes.
View raw extracted JSON
{
"publication_year": 2023,
"study_type": "animal",
"exposure": {
"band": "RF",
"source": "mobile phone",
"frequency_mhz": 900,
"sar_wkg": null,
"duration": "Daily exposure/treatment for 56 days"
},
"population": "Adult male Wistar rats (120–150 g)",
"sample_size": 20,
"outcomes": [
"Spermatogonia (count/levels)",
"Sperm count",
"Sperm motility",
"Sperm morphology",
"Sperm progressivity",
"Serum luteinizing hormone",
"Serum testosterone",
"Glutathione peroxidase",
"Testicular histology (germ cells, Leydig cells, interstitium)"
],
"main_findings": "In rats exposed to 900 MHz RF-EMR, the study reports decreases in spermatogonia, sperm count, motility, morphology, and progressivity, along with reduced serum luteinizing hormone, testosterone, and glutathione peroxidase and histologic degeneration compared with controls. Concomitant Panax ginseng (200 mg/kg) administration reportedly attenuated these RF-EMR-associated alterations.",
"effect_direction": "mixed",
"limitations": [
"Animal study; findings may not generalize to humans.",
"Small group sizes (n=5 per group).",
"Specific exposure details beyond frequency (e.g., SAR, field strength, distance, device model) are not provided in the abstract.",
"The abstract does not describe blinding or randomization procedures beyond group assignment."
],
"evidence_strength": "low",
"confidence": 0.7800000000000000266453525910037569701671600341796875,
"peer_reviewed_likely": "yes",
"stance": "concern",
"stance_confidence": 0.7399999999999999911182158029987476766109466552734375,
"summary": "This rat study examined whether Panax ginseng protects against testicular changes associated with 900 MHz RF-EMR exposure described as from cell phones. The RF-EMR group showed reduced sperm parameters, lower reproductive hormones, reduced glutathione peroxidase, and testicular histologic degeneration versus controls. Panax ginseng co-treatment reportedly attenuated these changes, which the authors attribute to enhanced antioxidant capacity.",
"key_points": [
"Twenty male Wistar rats were assigned to four groups (control, ginseng only, RF-EMR only, RF-EMR plus ginseng) with n=5 per group.",
"RF-EMR exposure was at 900 MHz and interventions were administered daily for 56 days.",
"RF-EMR exposure was associated with worse sperm metrics (count, motility, morphology, progressivity) compared with controls.",
"RF-EMR exposure was associated with lower serum luteinizing hormone and testosterone in this experiment.",
"Glutathione peroxidase decreased in the RF-EMR group, suggesting reduced antioxidant enzyme activity under the study conditions.",
"Histology in the RF-EMR group showed degeneration of germ and Leydig cells and distorted interstitium, which was attenuated with ginseng co-treatment."
],
"categories": [
"Animal Studies",
"Reproductive Health",
"Mechanisms (Oxidative Stress)",
"Cell Phones"
],
"tags": [
"Panax Ginseng",
"Wistar Rats",
"Male Fertility",
"Testicular Histology",
"Sperm Count",
"Sperm Motility",
"Testosterone",
"Luteinizing Hormone",
"Glutathione Peroxidase",
"Oxidative Stress",
"900 MHz",
"Radiofrequency Exposure",
"Mobile Phones",
"Antioxidants"
],
"keywords": [
"Panax ginseng",
"radiofrequency electromagnetic radiation",
"RF-EMR",
"cell phone",
"testicular damage",
"male infertility",
"Wistar rat",
"900 MHz",
"sperm count",
"sperm motility",
"testosterone",
"luteinizing hormone"
],
"suggested_hubs": [
{
"slug": "cell-phones",
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"reason": "Study explicitly examines RF-EMR described as from cell phones and reproductive outcomes."
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"social": {
"tweet": "Rat study: 900 MHz RF-EMR exposure was associated with reduced sperm parameters, lower LH/testosterone, and testicular histologic changes; Panax ginseng co-treatment reportedly attenuated these effects (Nutrire, 2023).",
"facebook": "In a small rat experiment (n=20), 900 MHz RF-EMR exposure was linked to poorer sperm measures, lower reproductive hormones, and testicular tissue changes versus controls. Panax ginseng given alongside exposure reportedly reduced these alterations, which authors relate to antioxidant capacity (Nutrire, 2023).",
"linkedin": "Nutrire (2023) reports a rat study (n=20) where 900 MHz RF-EMR exposure was associated with impaired sperm parameters, reduced LH/testosterone, lower glutathione peroxidase, and testicular histologic degeneration. Concomitant Panax ginseng (200 mg/kg) reportedly attenuated these changes, suggesting a potential antioxidant-related protective effect under the study conditions."
}
}
AI can be wrong. Always verify against the paper.
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