Cell Phone Radiation Effect on Bone-to-Implant Osseointegration: A Preliminary Histologic Evaluation in Rabbits

PAPER manual 2019 Animal study Effect: harm Evidence: Low

Read original paper → DOI: 10.11607/jomi.7024 Evidence Lab

Abstract

Cell Phone Radiation Effect on Bone-to-Implant Osseointegration: A Preliminary Histologic Evaluation in Rabbits Kavyashree M, Harish PV, Mishra SK, Chowdhary R. Cell phone radiation wffect on bone-to-implant osseointegration: A preliminary histologic evaluation in rabbits. Int J Oral Maxillofac Implants. 2019 Feb 19. doi: 10.11607/jomi.7024. Abstract BACKGROUND AND PURPOSE: The increased use of cell phones has raised many questions as to whether their use is safe for patients with dental implants. This study aimed to assess the consequences of cell phone-emitted radiation on bone-to-implant osseointegration during the healing phase. MATERIALS AND METHODS: Twelve rabbits were grouped into three groups of four. Group 1 (control) was not exposed to electromagnetic radiation; group 2 (test) was exposed for 8 hours/day in speech mode and 16 hours/day in standby mode; and group 3 (test) was exposed for 24 hours continuously in standby mode for 3 months. Forty-eight implants were placed in tibia and femur bone of rabbits, and after 90 days the rabbits were sacrificed and bone surrounding the implant was retrieved. Histopathologic evaluations of the specimens were done using transmitted light microscope. The differences among the three groups were statistically analyzed with analysis of variance (ANOVA) and pairwise comparisons via Fisher's exact test. RESULTS: Significantly less bone-to-implant contact and bone area surrounding implant threads were found in the test groups compared to the control group. There was a significant difference in regular bone formation (P < .001) among the three groups. CONCLUSION: Implants exposed to cell phone radiation showed more inflammatory reaction when compared to the nonexposed implants, thus indicating that cellular phone overuse could affect the maturation of bone and thus delay osseointegration. ncbi.nlm.nih.gov

AI evidence extraction

At a glance

Study type

Animal study

Effect direction

harm

Population

Rabbits

Sample size

Exposure

RF mobile phone · 3 months; Group 2: 8 h/day speech + 16 h/day standby; Group 3: 24 h/day standby

Evidence strength

Low

Confidence: 78% · Peer-reviewed: yes

Main findings

In this rabbit implant model, the exposed groups had significantly less bone-to-implant contact and less bone area surrounding implant threads compared with controls. The authors also report more inflammatory reaction in exposed implants and a significant difference in regular bone formation among groups.

Outcomes measured

Bone-to-implant contact
Bone area surrounding implant threads
Regular bone formation
Inflammatory reaction around implants
Osseointegration during healing phase

Limitations

Preliminary animal study with small group sizes (4 rabbits per group)
Exposure parameters (e.g., frequency, SAR) not reported in the abstract
Histologic outcomes in rabbits may not directly translate to humans with dental implants
Details on blinding/randomization are not provided in the abstract

Suggested hubs

cell-phones (0.95)
Study evaluates effects of cell phone-emitted radiation exposure conditions on biological outcomes.

View raw extracted JSON

{
    "publication_year": null,
    "study_type": "animal",
    "exposure": {
        "band": "RF",
        "source": "mobile phone",
        "frequency_mhz": null,
        "sar_wkg": null,
        "duration": "3 months; Group 2: 8 h/day speech + 16 h/day standby; Group 3: 24 h/day standby"
    },
    "population": "Rabbits",
    "sample_size": 12,
    "outcomes": [
        "Bone-to-implant contact",
        "Bone area surrounding implant threads",
        "Regular bone formation",
        "Inflammatory reaction around implants",
        "Osseointegration during healing phase"
    ],
    "main_findings": "In this rabbit implant model, the exposed groups had significantly less bone-to-implant contact and less bone area surrounding implant threads compared with controls. The authors also report more inflammatory reaction in exposed implants and a significant difference in regular bone formation among groups.",
    "effect_direction": "harm",
    "limitations": [
        "Preliminary animal study with small group sizes (4 rabbits per group)",
        "Exposure parameters (e.g., frequency, SAR) not reported in the abstract",
        "Histologic outcomes in rabbits may not directly translate to humans with dental implants",
        "Details on blinding/randomization are not provided in the abstract"
    ],
    "evidence_strength": "low",
    "confidence": 0.7800000000000000266453525910037569701671600341796875,
    "peer_reviewed_likely": "yes",
    "stance": "concern",
    "stance_confidence": 0.8000000000000000444089209850062616169452667236328125,
    "summary": "This preliminary rabbit study evaluated whether cell phone-emitted electromagnetic radiation affects bone-to-implant osseointegration during healing. Compared with nonexposed controls, exposed groups showed significantly less bone-to-implant contact and less bone area around implant threads, along with reported increased inflammatory reaction. The authors conclude that heavy cell phone exposure could delay osseointegration by affecting bone maturation.",
    "key_points": [
        "Twelve rabbits were assigned to three groups (control and two exposure conditions) for 3 months.",
        "Exposure conditions included prolonged daily speech/standby use or continuous standby exposure.",
        "Forty-eight implants were placed in rabbit tibia and femur, and histology was assessed after 90 days.",
        "Test groups had significantly less bone-to-implant contact than controls.",
        "Test groups had significantly less bone area surrounding implant threads than controls.",
        "Regular bone formation differed significantly among groups, and exposed implants showed more inflammatory reaction per the authors."
    ],
    "categories": [
        "Animal Studies",
        "Dental Implants",
        "RF Exposure"
    ],
    "tags": [
        "Cell Phone Radiation",
        "Osseointegration",
        "Dental Implants",
        "Rabbit Model",
        "Histologic Evaluation",
        "Bone-To-Implant Contact",
        "Inflammation",
        "Standby Mode Exposure",
        "Speech Mode Exposure"
    ],
    "keywords": [
        "cell phone",
        "radiation",
        "electromagnetic radiation",
        "osseointegration",
        "bone-to-implant contact",
        "rabbit",
        "implant",
        "inflammation",
        "histopathology"
    ],
    "suggested_hubs": [
        {
            "slug": "cell-phones",
            "weight": 0.9499999999999999555910790149937383830547332763671875,
            "reason": "Study evaluates effects of cell phone-emitted radiation exposure conditions on biological outcomes."
        }
    ],
    "social": {
        "tweet": "Rabbit implant study reports reduced bone-to-implant contact and more inflammation after prolonged cell phone radiation exposure vs controls; authors suggest possible delayed osseointegration.",
        "facebook": "A preliminary rabbit study of dental implants found significantly less bone-to-implant contact and less bone around implant threads in groups exposed to cell phone-emitted radiation compared with nonexposed controls, with more inflammatory reaction reported.",
        "linkedin": "In a preliminary animal model (rabbits), prolonged exposure to cell phone-emitted electromagnetic radiation during healing was associated with significantly reduced bone-to-implant contact and bone area around implant threads versus controls, alongside reported increased inflammation."
    }
}

AI can be wrong. Always verify against the paper.

AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

Comments

No comments yet.