Effect of cell phone radiation on neutrophil of mice

PAPER manual 2019 Animal study Effect: mixed Evidence: Low

Read original paper → DOI: 10.1080/09553002.2019.1607605 Evidence Lab

Abstract

Effect of cell phone radiation on neutrophil of mice Pei Y, Gao H, Li L, An X, Tian Q. Effect of cell phone radiation on neutrophil of mice. Int J Radiat Biol. 2019 Apr 23:1-22. doi: 10.1080/09553002.2019.1607605. Abstract Purpose The present study aims to evaluate the effect of cell phone radiation on neutrophil of mice. Materials and methods 40 male BALB/C mice were randomly broken up into 4 groups as control, blank control, TD-CDMA and LTE-Advanced groups respectively. Mice were exposed to cell phone radiation for a period of 6 weeks. Then numbers of neutrophil were detected by fully automatic haematology analyzer. Soft agar diffusion method was performed to assess the chemotaxis of neutrophils while the phagocytosis of neutrophils was determined by measuring the staphylococcus albus phagocytosis percentage. Apoptosis was analyzed by flow cytometry. Results No significant differences were observed among the control and exposure groups regarding the numbers of neutrophils after 2 weeks' exposure to cell phone radiation, while the numbers of neutrophils in TD-SCDMA and LTE-Advanced groups were seen to rise after an exposure of 4 or 6 weeks. No effect was observed on chemotaxis of neutrophils due to phone radiation. The phagocytosis of neutrophils was decreased while the apoptosis were increased both in TD-SCDMA and LTE-Advanced groups after 6 weeks exposure. Conclusions Mobile phone radiation could give rise to increase of neutrophil numbers yet with no effect whatever on neutrophils chemotaxis, and the radiation was likely to cause decrease of phagocytosis and induced apoptosis of neutrophils. ncbi.nlm.nih.gov

AI evidence extraction

At a glance

Study type

Animal study

Effect direction

mixed

Population

40 male BALB/C mice

Sample size

Exposure

RF mobile phone · 6 weeks

Evidence strength

Low

Confidence: 74% · Peer-reviewed: yes

Main findings

After 2 weeks, neutrophil numbers did not differ between control and exposure groups. Neutrophil numbers increased in TD-SCDMA and LTE-Advanced groups after 4 or 6 weeks; chemotaxis showed no observed effect; after 6 weeks phagocytosis decreased and apoptosis increased in both exposure groups.

Outcomes measured

Neutrophil count
Neutrophil chemotaxis
Neutrophil phagocytosis (staphylococcus albus phagocytosis percentage)
Neutrophil apoptosis

Limitations

Exposure parameters (e.g., frequency, SAR) not reported in the abstract
Animal study; generalizability to humans is unclear from the abstract
Details of blinding, randomization procedures, and statistical methods not provided in the abstract

Suggested hubs

mobile-phones-rf (0.9)
Exposure described as cell phone/mobile phone radiation with TD-SCDMA and LTE-Advanced groups.

View raw extracted JSON

{
    "study_type": "animal",
    "exposure": {
        "band": "RF",
        "source": "mobile phone",
        "frequency_mhz": null,
        "sar_wkg": null,
        "duration": "6 weeks"
    },
    "population": "40 male BALB/C mice",
    "sample_size": 40,
    "outcomes": [
        "Neutrophil count",
        "Neutrophil chemotaxis",
        "Neutrophil phagocytosis (staphylococcus albus phagocytosis percentage)",
        "Neutrophil apoptosis"
    ],
    "main_findings": "After 2 weeks, neutrophil numbers did not differ between control and exposure groups. Neutrophil numbers increased in TD-SCDMA and LTE-Advanced groups after 4 or 6 weeks; chemotaxis showed no observed effect; after 6 weeks phagocytosis decreased and apoptosis increased in both exposure groups.",
    "effect_direction": "mixed",
    "limitations": [
        "Exposure parameters (e.g., frequency, SAR) not reported in the abstract",
        "Animal study; generalizability to humans is unclear from the abstract",
        "Details of blinding, randomization procedures, and statistical methods not provided in the abstract"
    ],
    "evidence_strength": "low",
    "confidence": 0.7399999999999999911182158029987476766109466552734375,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "mobile phone radiation",
        "cell phone",
        "RF exposure",
        "TD-SCDMA",
        "LTE-Advanced",
        "mice",
        "BALB/C",
        "neutrophils",
        "chemotaxis",
        "phagocytosis",
        "apoptosis"
    ],
    "suggested_hubs": [
        {
            "slug": "mobile-phones-rf",
            "weight": 0.90000000000000002220446049250313080847263336181640625,
            "reason": "Exposure described as cell phone/mobile phone radiation with TD-SCDMA and LTE-Advanced groups."
        }
    ]
}

AI can be wrong. Always verify against the paper.

AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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