The effect of exposure to RF-EMF from the laboratory simulator of 5G NR base station on physiological parameters and cognitive abilities of male wistar rats of different ages

PAPER manual Sci Rep. 2024 Animal study Effect: no_effect Evidence: Low

Read original paper → DOI: 10.1038/s41598-024-60862-5 Evidence Lab

Abstract

Effect of exposure to RF-EMF from lab simulator of 5G NR base station on physiological parameters & cognitive abilities of male rats of different ages (My note: Methodological limitations of this study reduce generalizability to real-world 5G exposures.) Krivova NA, Kudabaeva MS, Zaeva OB et al. The effect of exposure to RF-EMF from the laboratory simulator of 5G NR base station on physiological parameters and cognitive abilities of male wistar rats of different ages. Sci Rep 14, 10283 (2024). doi: 10.1038/s41598-024-60862-5. Abstract In this article, the impact of radiofrequency electromagnetic field (RF-EMF) exposure from a simulated base station for the 5G New Radio (5G NR) telecommunication on rats was studied. The base station affects all age groups of the population, thus, for the first time, the experiment was conducted on male Wistar rats of three different ages (juvenile, adult, and presenile). The base station exposure parameters were chosen according to ICNIRP recommendations for limiting the exposure to radiofrequency electromagnetic field: frequency 2.4 GHz with an average specific absorption rate of 0.0076 W/kg and 0.0059 W/kg over the whole body of experimental animals. Throughout the experiment, body weight was examined weekly, and the dynamics of body weight gain was monitored. Rectal and skin surface temperature on the right hind limb was monitored weekly. Testing in the Morris water maze was performed during the last, Week 5, of RF-EMF exposure. After euthanasia, organ weights were determined in experimental and control animals. None of the investigated parameters did show any statistically significant differences between exposed and control animals of the same age. The data obtained can be used to assess the possible consequences of chronic exposure to RF-EMF from 5G NR base stations. Open access paper: nature.com

AI evidence extraction

At a glance

Study type

Animal study

Effect direction

no_effect

Population

Male Wistar rats (juvenile, adult, presenile)

Sample size

—

Exposure

RF 5G NR base station simulator · 2400 MHz · 0.0076 W/kg · 5 weeks

Evidence strength

Low

Confidence: 78% · Peer-reviewed: yes

Main findings

Across juvenile, adult, and presenile male Wistar rats, no statistically significant differences were observed between RF-EMF-exposed and control animals of the same age for body weight/gain, rectal and skin temperature, Morris water maze testing, or organ weights after 5 weeks of exposure.

Outcomes measured

Body weight and body weight gain dynamics
Rectal temperature
Skin surface temperature (right hind limb)
Cognitive performance (Morris water maze)
Organ weights (post-euthanasia)

Limitations

Sample size not reported in the provided abstract/metadata
Only male rats studied
Exposure frequency reported as 2.4 GHz (may not represent all 5G NR base station frequencies)
Only selected physiological parameters, organ weights, and one cognitive test assessed
Exposure duration limited to 5 weeks

Suggested hubs

who-icnirp (0.6)
Exposure parameters were chosen according to ICNIRP recommendations.
5g-policy (0.55)
Study evaluates simulated 5G NR base station RF-EMF exposure.

View raw extracted JSON

{
    "study_type": "animal",
    "exposure": {
        "band": "RF",
        "source": "5G NR base station simulator",
        "frequency_mhz": 2400,
        "sar_wkg": 0.007599999999999999984734433411404097569175064563751220703125,
        "duration": "5 weeks"
    },
    "population": "Male Wistar rats (juvenile, adult, presenile)",
    "sample_size": null,
    "outcomes": [
        "Body weight and body weight gain dynamics",
        "Rectal temperature",
        "Skin surface temperature (right hind limb)",
        "Cognitive performance (Morris water maze)",
        "Organ weights (post-euthanasia)"
    ],
    "main_findings": "Across juvenile, adult, and presenile male Wistar rats, no statistically significant differences were observed between RF-EMF-exposed and control animals of the same age for body weight/gain, rectal and skin temperature, Morris water maze testing, or organ weights after 5 weeks of exposure.",
    "effect_direction": "no_effect",
    "limitations": [
        "Sample size not reported in the provided abstract/metadata",
        "Only male rats studied",
        "Exposure frequency reported as 2.4 GHz (may not represent all 5G NR base station frequencies)",
        "Only selected physiological parameters, organ weights, and one cognitive test assessed",
        "Exposure duration limited to 5 weeks"
    ],
    "evidence_strength": "low",
    "confidence": 0.7800000000000000266453525910037569701671600341796875,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "RF-EMF",
        "5G NR",
        "base station simulator",
        "ICNIRP",
        "Wistar rats",
        "juvenile",
        "adult",
        "presenile",
        "specific absorption rate",
        "Morris water maze",
        "temperature",
        "organ weights"
    ],
    "suggested_hubs": [
        {
            "slug": "who-icnirp",
            "weight": 0.59999999999999997779553950749686919152736663818359375,
            "reason": "Exposure parameters were chosen according to ICNIRP recommendations."
        },
        {
            "slug": "5g-policy",
            "weight": 0.5500000000000000444089209850062616169452667236328125,
            "reason": "Study evaluates simulated 5G NR base station RF-EMF exposure."
        }
    ]
}

AI can be wrong. Always verify against the paper.

AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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