Effect of RFEMR on NSE and MDA levels in Sprague Dawley rats

PAPER manual 2022 Animal study Effect: harm Evidence: Low

Read original paper → Evidence Lab

Abstract

Effect of RFEMR on NSE and MDA levels in Sprague Dawley rats Pagadala, P; Shankar, V and Sumathi, ME. Effect of RFEMR on NSE and MDA levels in Sprague Dawley rats. Jun 2022. Bioinformation.18 (6): 501-505. Abstract Radiofrequency emitted radiations (RFEMR) from mobile phones are known to produce a stress response because of its effect on hypothalamus. Mobile phones have become an integral part of our lives with increasing usage not only in terms of number of users but also increase in talk time. Therefore, it is of interest to study the effect of mobile phone radiofrequency electromagnetic radiations on NSE and MDA levels in SD rats. Twelve male SD rats of 10-12weeks old, weighing 180-220 grams, were purchased from registered laboratory breeders & housed in a room with 12:12hour's light-dark cycle with adlibitum amount of food and RO water. Present study showed significant increase in NSE and MDA levels in rats exposed to RFEMR. This study proves that mobile RFEMR causes oxidative stress and oxidative damage in SD rats. bioinformation.net

AI evidence extraction

At a glance

Study type

Animal study

Effect direction

harm

Population

Male Sprague Dawley rats (10–12 weeks old; 180–220 g)

Sample size

Exposure

RF mobile phone

Evidence strength

Low

Confidence: 72% · Peer-reviewed: yes

Main findings

The study reports a significant increase in NSE and MDA levels in rats exposed to mobile phone RFEMR.

Outcomes measured

NSE levels
MDA levels
Oxidative stress/oxidative damage (as interpreted by authors)

Limitations

Exposure parameters (e.g., frequency, SAR, duration) not reported in the abstract
No details provided on control/sham conditions in the abstract
Small sample size

Suggested hubs

mobile-phones (0.9)
Exposure described as radiofrequency electromagnetic radiation from mobile phones.

View raw extracted JSON

{
    "study_type": "animal",
    "exposure": {
        "band": "RF",
        "source": "mobile phone",
        "frequency_mhz": null,
        "sar_wkg": null,
        "duration": null
    },
    "population": "Male Sprague Dawley rats (10–12 weeks old; 180–220 g)",
    "sample_size": 12,
    "outcomes": [
        "NSE levels",
        "MDA levels",
        "Oxidative stress/oxidative damage (as interpreted by authors)"
    ],
    "main_findings": "The study reports a significant increase in NSE and MDA levels in rats exposed to mobile phone RFEMR.",
    "effect_direction": "harm",
    "limitations": [
        "Exposure parameters (e.g., frequency, SAR, duration) not reported in the abstract",
        "No details provided on control/sham conditions in the abstract",
        "Small sample size"
    ],
    "evidence_strength": "low",
    "confidence": 0.7199999999999999733546474089962430298328399658203125,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "RFEMR",
        "radiofrequency",
        "mobile phone",
        "Sprague Dawley rats",
        "NSE",
        "MDA",
        "oxidative stress"
    ],
    "suggested_hubs": [
        {
            "slug": "mobile-phones",
            "weight": 0.90000000000000002220446049250313080847263336181640625,
            "reason": "Exposure described as radiofrequency electromagnetic radiation from mobile phones."
        }
    ]
}

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AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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