"Oxidative mechanisms of biological activity of low-intensity radiofrequency radiation" by Yakymenko I, Tsybulin O, Sidorik E, Henshel D, Kyrylenko O, Kyrylenko S.
- Published in Electromagnetic Biology and Medicine (online 2015, print 2016).
- They reviewed ~100 peer-reviewed experimental studies (in vitro and in vivo, across cells, animals, plants, etc.) on oxidative effects of low-intensity RF.
- 93 out of 100 studies (93%) confirmed significant oxidative effects — including ROS overproduction, lipid peroxidation, oxidative DNA damage, and changes in antioxidant enzymes.
- This established oxidative stress as a primary non-thermal mechanism for RF biological activity (with pathogenic potential for cancer, etc.).
- PubMed abstract: https://pubmed.ncbi.nlm.nih.gov/26151230/
- Full PDF (open access via EHT): https://ehtrust.org/wp-content/uploads/Yakymenko-et-al-2015.pdf
- Taylor & Francis: https://www.tandfonline.com/doi/full/10.3109/15368378.2015.1138125
- Reviewed 131 peer-reviewed studies on oxidative effects of non-thermal RF/wireless communication EMFs (mostly pulsed/modulated).
- 124 out of 131 (≈95%) confirmed statistically significant oxidative effects.
- They also noted 36/39 (92%) for purely ELF EMFs.
- This was discussed/expanded in the 2025 comprehensive review co-authored by Yakymenko: "A comprehensive mechanism of biological and health effects of anthropogenic extremely low frequency and wireless communication electromagnetic fields" by Panagopoulos DJ, Yakymenko I, De Iuliis GN, Chrousos GP (Frontiers in Public Health, 2025). It ties oxidative stress (via voltage-gated ion channel dysfunction → ROS → DNA damage) to broader effects like infertility, cancer, EHS, etc.
- 2025 comprehensive paper (open access, cites the Yakymenko/Tsibulin update): https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2025.1585441/full
- Related 2022 book chapter by Yakymenko & Tsybulin ("Oxidative Stress Induced by Wireless Communication Electromagnetic Fields"): https://www.taylorfrancis.com/chapters/edit/10.1201/9781003201052-6/oxidative-stress-induced-wireless-communication-electromagnetic-fields-igor-yakymenko-oleksandr-tsybulin