The International Collaborative Animal Study of The Carcinogenicity and Genotoxicity of Mobile Phone Radiofrequency Radiation: The Korean Study.
Research
RF Safe Research Library
Jan 1, 2026
This chronic animal bioassay assessed carcinogenicity and genotoxicity of CDMA-modulated 900 MHz RF exposure at a whole-body SAR of 4 W/kg using a shared Korea–Japan protocol. Male Sprague-Dawley rats were exposed starting on gestational day 5 with daily intermittent exposure for long durations, including a 2-year…
Development and Testing of a Novel Whole-body Exposure System for Investigative Studies of Radiofrequency Radiation in Rodents (NIEHS)
Research
RF Safe Research Library
Jan 1, 2025
This NIEHS report describes the development and testing of a flexible whole-body radiofrequency radiation exposure system for rats and mice using updated signals relevant to wireless technologies. In 5-day studies with CDMA- and GSM-modulated signals, no visible behavioral responses were observed and comet assays…
NTP Lite: The Japan-Korea Collaborative RF Exposure Toxicity Project [Health Matters]
Research
RF Safe Research Library
Jan 1, 2025
This magazine article reviews the Japan-Korea "NTP Lite" RF animal toxicity collaboration and its relationship to prior NTP (2018) and Ramazzini Institute reports of RF-associated tumors in male rats. It notes NTP Lite used a single whole-body SAR of 4 W/kg and completed a two-year exposure phase in 2022, but final…
Time-Dependence Effect of 2.45 GHz RF-EMR Exposure on Male Reproductive Hormones and LHCGR
Research
RF Safe Research Library
Jan 1, 2025
This animal study exposed male Sprague Dawley rats to 2.45 GHz Wi-Fi for varying daily durations over eight weeks and assessed reproductive hormones and LHCGR expression. Serum LH and testosterone did not differ significantly from controls, but LHCGR mRNA increased with longer exposure and LHCGR protein showed…
Simultaneous 4G and 5G EMF Exposure and Field Uniformity in a Reverberation Chamber for Animal Studies
Research
RF Safe Research Library
Jan 1, 2025
This engineering study describes the design and validation of a reverberation chamber intended for large-scale animal carcinogenicity research with RF EMF relevant to 4G/5G. E-field uniformity was tested under four loading scenarios, including setups with 80 Sprague-Dawley rats. The chamber achieved better than 1.36…
Characterization of the Core Temperature Response of Free-Moving Rats to 1.95 GHz Electromagnetic Fields
Research
RF Safe Research Library
Jan 1, 2025
This animal study measured core body temperature in free-moving male and female Sprague Dawley rats during and after 3-hour exposure to 1.95 GHz RF-EMF at multiple whole-body average SAR levels. A measurable thermal response was reported at 4 W/kg, while lower SAR conditions showed smaller or no significant…
Effects of non-ionizing radiation on the thyroid gland in rats
Research
RF Safe Research Library
Jan 1, 2025
This animal study exposed Sprague-Dawley rats (including pregnant females and offspring) to 2.45 GHz Wi-Fi or mobile jammer radiation for 2 hours daily over two weeks and assessed thyroid hormones and thyroid histology. The abstract reports significant changes in T4 in exposed adult males and significant differences…
Histomorphometry and Sperm Quality in Male Rats Exposed to 2.45 GHz Wi-Fi
Research
RF Safe Research Library
Jan 1, 2025
This animal study exposed adult male rats to 2.45 GHz Wi‑Fi from an active router for 4 or 24 hours daily over eight weeks and assessed reproductive organ histology and sperm parameters. The authors report histological changes in testes and epididymis, multifocal atypical hyperplasia in seminal vesicles, reduced…
Electromagnetic field stimulation for long-term mobility assessment after sciatic nerve injury.
Research
RF Safe Research Library
Jan 1, 2025
This animal study evaluated electromagnetic field (EMF) stimulation as a treatment after sciatic nerve injury in male Sprague-Dawley rats. Rats received low-intensity (60–100 G; 6–10 mT) or high-intensity (140–200 G; 14–20 mT) EMF exposure for 2 hours/day over 4 weeks. The abstract reports improved motor/mobility…
The Time-Dependence of Three Different Modes of ELF-EMF Stimulation on LTP at Schaffer Collateral-CA1 Synapses.
Research
RF Safe Research Library
Jan 1, 2021
This animal ex vivo study tested whether short-term 15 Hz/2 mT ELF-EMF exposure alters LTP at rat hippocampal SC-CA1 synapses. Across sinusoidal, pulsed, and rhythm-pulsed modes, the authors report reduced LTP versus control, with greater inhibition at longer exposure durations (10–60 s). Sinusoidal stimulation…
Toxicology and carcinogenesis studies in Sprague Dawley (Hsd:Sprague Dawley SD) rats exposed to whole-body radio frequency radiation at a frequency (900 MHz) and modulations (GSM and CDMA) used by cell phones
Research
RF Safe Research Library
Jan 1, 2018
This National Toxicology Program technical report describes 900 MHz whole-body RFR exposures (GSM and CDMA) in male and female Sprague Dawley rats from in utero through up to 2 years. The report concludes clear evidence of carcinogenic activity in males for both modulations based on malignant schwannoma of the heart,…
Effect of Exposure to 900 MHz GSM Mobile Phone Radiofrequency Radiation on Estrogen Receptor Methylation Status in Colon Cells of Male Sprague Dawley Rats
Research
RF Safe Research Library
Mar 1, 2017
This animal study exposed male Sprague-Dawley rats to 900 MHz GSM mobile phone RF radiation for 4 hours and assessed ERα promoter methylation in colon tissue. The authors report altered ERα methylation patterns versus controls after RF exposure. They also report no radioadaptive response in ERα methylation following…
[Effects of 1.8 mT sinusoidal alternating electromagnetic fields of different frequencies on bone biomechanics of young rats].
Research
RF Safe Research Library
Jan 1, 2016
This randomized animal experiment exposed 32 young female rats to 1.8 mT sinusoidal alternating electromagnetic fields at 10, 25, or 40 Hz for 90 minutes per day. The 10 Hz and 40 Hz groups had higher BMD and improved femur and lumbar vertebra biomechanical properties compared with controls, and micro-CT suggested…
Impact of 900 MHz electromagnetic field exposure on main male reproductive hormone levels: a Rattus norvegicus model
Research
RF Safe Research Library
Jan 1, 2014
This animal experiment exposed 20 adult male Sprague-Dawley rats to 900 MHz RF-EMF for 1, 2, or 4 hours per day over 30 days, with a sham-exposed control group. Hormone levels (FSH, LH, inhibin B, activin B, prolactin, testosterone) were measured by ELISA before exposure and at 15 and 30 days. After 30 days, the long…
The influence of low-frequency magnetic field on plasma antioxidant capacity and heart rate.
Research
RF Safe Research Library
Jan 1, 2009
This animal study exposed Sprague-Dawley rats to a 40 Hz, 7 mT time-variable magnetic field and measured ECG heart rate and plasma antioxidant capacity before and after exposure, including after 14 days. The authors report a significant decrease in heart rate after 14 days. Antioxidant defence findings were mixed,…