This review discusses preclinical studies suggesting non-ionizing EMF exposures can produce beneficial biological effects, while noting ongoing controversy about mechanisms. It reports evidence of EMF-associated conformational changes in intrinsically disordered proteins relevant to neurodegeneration and describes RF exposure conditions that activate proteostasis and autophagy in cell and animal models. The authors propose a quantum-biophysical framework involving the water-protein interface and suggest potential human applications within regulatory safety thresholds.