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Filters: tag: Leydig Cells Clear

Time-Dependence Effect of 2.45 GHz RF-EMR Exposure on Male Reproductive Hormones and LHCGR

Research RF Safe Research Library Jan 1, 2025

This animal study exposed male Sprague Dawley rats to 2.45 GHz Wi-Fi for varying daily durations over eight weeks and assessed reproductive hormones and LHCGR expression. Serum LH and testosterone did not differ significantly from controls, but LHCGR mRNA increased with longer exposure and LHCGR protein showed…

Non-thermal biological effects of radiofrequency electromagnetic radiation: Mechanistic insights into male reproductive vulnerability in the era of ubiquitous exposure

Research RF Safe Research Library Jan 1, 2025

This narrative review discusses proposed non-thermal mechanisms by which chronic, low-intensity RF-EMR from ubiquitous wireless sources may affect male reproductive health. It highlights oxidative stress, mitochondrial dysfunction, impaired testosterone synthesis/steroidogenesis, and declines in sperm quality as…

Differential metabolic responses of mouse Leydig and spermatogonia cells to radiofrequency electromagnetic field exposure

Research RF Safe Research Library Jan 1, 2025

This in vitro study used LC-MS metabolomics to assess how continuous versus intermittent RF-EMF irradiation affects mouse Leydig (TM3) and spermatogonia (GC-1) cells. The authors report stronger metabolic disturbances in TM3 cells under continuous exposure, including changes in amino acid and glutathione-related…

Mitigating Heat-Induced Sperm Damage and Testicular Tissue Abnormalities: The Protective Role of Radiofrequency Radiation from Wi-Fi Routers in Rodent Models

Research RF Safe Research Library Jan 1, 2024

This rodent study examined whether 2.45 GHz Wi‑Fi router RF-EMF exposure could mitigate heat-stress-related reproductive damage in male rats. The combined RF-EMF + heat group reportedly had improved testicular structure measures and sperm quality versus heat-only, while RF-EMF alone was also reported to alter testis…

Protective effects of luteolin on rat testis following exposure to 900 MHz electromagnetic field.

Research RF Safe Research Library Jan 1, 2019

This rat study examined 900 MHz EMF exposure effects on testes and whether luteolin modifies those effects. EMF exposure was associated with reduced testicular cell counts, lower testis weight and serum testosterone, increased SOD activity, and changes in sperm morphology versus controls. Luteolin co-treatment was…

Effect of Electromagnetic Waves from Mobile Phones on Spermatogenesis in the Era of 4G-LTE.

Research RF Safe Research Library Jan 1, 2018

This animal experiment assessed whether long-duration 4G-LTE mobile phone electromagnetic field exposure affects spermatogenesis in male rats. After 1 month, the highest exposure condition (3 cm distance, 18 h/day) had reduced spermatid, spermatogonia, total germ cell, and Leydig cell counts compared with sham and…

Down-regulation of metallothionein 1 and 2 after exposure to electromagnetic field in mouse testis.

Research RF Safe Research Library Jan 1, 2011

This animal study examined mouse testis after 8 weeks of exposure to a 3 MT electromagnetic field (4 hours/day). The authors report significant histological changes (increased primary spermatocytes, increased Leydig cells, and increased basement membrane thickness) in exposed mice versus controls. MT1 and MT2…

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