Intermittent Exposure to a 16 Hz Extremely Low Frequency Pulsed Electromagnetic Field Promotes Osteogenesis In Vitro through Activating Piezo 1-Induced Ca Influx in Osteoprogenitor Cells.
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study compared continuous versus intermittent 16 Hz ELF-PEMF exposure strategies in osteoprogenitor (SCP-1) cells. Intermittent exposure (10 min every 8 h) was reported to enhance cell numbers and osteogenic function relative to continuous daily exposure (30 min every 24 h). The authors report increased…
EVALUATION OF BCL2 AND ITS REGULATORY MIRS, MIR-15-B AND MIR-16 EXPRESSION CHANGES UNDER THE EXPOSURE OF EXTREMELY LOW-FREQUENCY ELECTROMAGNETIC FIELDS ON HUMAN GASTRIC CANCER CELL LINE.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study examined whether extremely low-frequency electromagnetic fields (ELF-EMF) at 0.2 or 2 mT (continuous or 1.5 h on/1.5 h off) for 18 hours alter viability and gene/miRNA expression in AGS gastric cancer cells. The authors report a significant reduction in cell viability at 2 mT continuous exposure.…
Up-regulation of miR-144 and miR-375 in the human gastric cancer cell line following the exposure to extremely low-frequency electromagnetic fields.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study exposed AGS human gastric cancer cells to 50 Hz ELF magnetic fields at 0.2 or 2 mT for 18 hours (continuous or intermittent). The authors report reduced cell viability versus control and up-regulation of miR-144 and miR-375 during exposure. They also report miR levels decreased 18 and 36 hours…
Effects of electromagnetic field, cisplatin and morphine on cytotoxicity and expression levels of DNA repair genes.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study examined how morphine, a 50-Hz 0.50 mT electromagnetic field (intermittent), and cisplatin co-treatments affected DNA repair gene expression and cytotoxicity in MCF-7 and SH-SY5Y cells. Morphine alone was reported to down-regulate examined DNA repair genes, whereas morphine plus EMF did not…
Expressions of some antioxidant genes in SH-SY5Y cells treated with β-lapachone, morphine and electromagnetic field.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study exposed SH-SY5Y cells to a 50 Hz, 0.50 mT electromagnetic field under intermittent or continuous conditions, alongside β-lapachone and/or morphine. The authors report condition-dependent changes in antioxidant gene expression, including decreased NQO1 and increased NQO2 under intermittent EMF…
Vitamin C and Vitamin E Protected B and Balb/c-3T3 Cells from Apoptosis Induced by Intermittent 50Hz ELF-EMF Radiation.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study exposed B cells and Balb/c-3T3 cells to intermittent 50 Hz power-line ELF-EMF and assessed apoptosis. The authors report that preincubation with vitamin C or vitamin E reduced apoptosis compared with the exposed group. They conclude that vitamins C and E have protective effects, with stronger…
[Effect of 1.8 GHz radiofrequency electromagnetic fields on gene expression of rat neurons].
Research
RF Safe Research Library
Jan 1, 2008
This in vitro study exposed primary cultured rat neurons to 1.8 GHz RF-EMF at an average SAR of 2 W/kg and assessed gene expression changes. The authors report multiple differentially expressed genes after 24 h intermittent exposure and confirm exposure-dependent changes in Egr-1, Mbp, and Plp by semi-quantitative…