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Filters: tag: Genotoxicity Clear

The International Collaborative Animal Study of Mobile Phone Radiofrequency Radiation Carcinogenicity and Genotoxicity: The Japanese Study

Research RF Safe Research Library Jan 1, 2026

This international collaborative animal study (Japanese arm) evaluated carcinogenicity and genotoxicity in male Sprague Dawley rats exposed long-term to 900 MHz CDMA-modulated RF-EMFs at 4 W/kg whole-body SAR. The abstract reports no statistically significant increases in neoplastic or non-neoplastic lesions in major…

Exposure to hexavalent chromium and 1800 MHz electromagnetic radiation can synergistically induce intracellular DNA damage in mouse embryonic fibroblasts

Research RF Safe Research Library Jan 1, 2026

This in vitro study tested whether 1800 MHz RF-EMF modifies chemically induced DNA damage in mouse embryonic fibroblasts under non-thermal exposure conditions. RF-EMF alone did not produce detectable DNA damage and did not significantly enhance damage from hydrogen peroxide, 4NQO, or cadmium. In contrast, co-exposure…

NTP Lite: The Japan-Korea Collaborative RF Exposure Toxicity Project [Health Matters]

Research RF Safe Research Library Jan 1, 2025

This magazine article reviews the Japan-Korea "NTP Lite" RF animal toxicity collaboration and its relationship to prior NTP (2018) and Ramazzini Institute reports of RF-associated tumors in male rats. It notes NTP Lite used a single whole-body SAR of 4 W/kg and completed a two-year exposure phase in 2022, but final…

A Systematic Review of the Impact of Electromagnetic Waves on Living Beings

Research RF Safe Research Library Jan 1, 2025

This PRISMA-adherent systematic review searched PubMed, Scopus, and the Cochrane Library for studies (2017–2024) on physiological or behavioral responses to EMF exposure, emphasizing studies reporting harmful or concerning effects. Across 24 included studies (human non-randomized, in vitro, and animal), the review…

Effect of electromagnetic radiations from mobile towers on genetic damage and genetic polymorphism in humans: a review on India's perspective

Research RF Safe Research Library Jan 1, 2025

This narrative review examines research on radiofrequency electromagnetic radiation (RF-EMR) from mobile towers and its potential association with genetic damage and genetic polymorphism in humans, with an emphasis on India. The abstract states that RF-EMR exposure may affect genetic material and suggests a link…

A scoping review and evidence map of radiofrequency field exposure and genotoxicity: assessing in vivo, in vitro, and epidemiological data

Research RF Safe Research Library Jan 1, 2025

This scoping review and evidence map (PRISMA-ScR) summarizes over 500 studies on RF-EMF exposure and genotoxicity across in vitro, in vivo, and epidemiological research. The authors report a higher proportion of significant DNA damage findings in in vivo and epidemiological studies than in vitro studies, with DNA…

Genotoxic and histopathological effects of 6 GHz radiofrequency electromagnetic radiation on rat liver tissue

Research RF Safe Research Library Jan 1, 2025

This animal experiment exposed adult male rats to 6 GHz RF-EMR (0.065 W/kg) for 4 hours/day over 42 days and compared them with sham controls. The exposed group showed higher comet assay genotoxicity metrics, though not statistically significant, and more prominent liver histopathological changes (e.g., portal…

Comparison of pulsed and continuous electromagnetic field generated by WPT system on human dermal and neural cells.

Research RF Safe Research Library Jan 1, 2024

This in vitro study tested electromagnetic fields generated by a prototype wireless power transfer (wireless charging) system on four human dermal and neural cell lines. Across pulsed and continuous exposure conditions, the authors report no negative effects on morphology/cytoskeleton, viability/mitosis,…

Genotoxic and cytotoxic effects of 50 Hz 1 mT electromagnetic field on larval rainbow trout (Oncorhynchus mykiss), Baltic clam (Limecola balthica) and common ragworm (Hediste diversicolor).

Research RF Safe Research Library Jan 1, 2019

This animal study assessed genotoxic and cytotoxic responses in aquatic species exposed to a 50 Hz, 1 mT electromagnetic field. Nuclear abnormality assays indicated significant increases in multiple genotoxicity endpoints across species, with the most pronounced effects in Baltic clam gill cells. Cytotoxicity…

Evaluation of Cytotoxic and Genotoxic Effects of Extremely Low-frequency Electromagnetic Field on Mesenchymal Stromal Cells.

Research RF Safe Research Library Jan 1, 2018

This in vitro study evaluated whether a therapeutic extremely low-frequency EMF exposure (5 Hz, 0.4 mT) causes cytotoxic or genotoxic effects in a human mesenchymal stromal cell line. Cells were exposed for 20 minutes per day, three times per week, for two weeks and assessed for viability, proliferation, and…

Electromagnetic fields at a mobile phone frequency (900 MHz) trigger the onset of general stress response along with DNA modifications in Eisenia fetida earthworms.

Research RF Safe Research Library Jan 1, 2017

This animal study exposed Eisenia fetida earthworms to 900 MHz electromagnetic fields at 10–120 V/m for 2 hours (with additional tests of longer exposure, modulation, and recovery). The authors report significant DNA modifications across exposure treatments and a decrease in probe hybridisation sites persisting after…

Effect of long-term exposure to mobile phone radiation on alpha-Int1 gene sequence of Candida albicans.

Research RF Safe Research Library Jan 1, 2016

This in vitro study evaluated whether long-term 900 MHz radiation exposure induces mutations in the alpha-Int1 gene of Candida albicans. Yeast samples were exposed for 10 to 490 hours at 4°C and compared with unexposed controls. Sequencing of the PCR-amplified alpha-Int1 fragment found no mutations in exposed samples…

A cross-sectional study on oxidative stress in workers exposed to extremely low frequency electromagnetic fields

Research RF Safe Research Library Jan 1, 2015

This cross-sectional study compared oxidative stress and genotoxicity biomarkers between 310 ELF-EMF-exposed inspection workers and 300 logistical staff controls. The authors report no statistically significant differences in antioxidant-related measures (T-AOC, GPx, SOD) or MDA, and no significant differences in…

Electromagnetic fields and DNA damage

Research RF Safe Research Library Jan 1, 2009

This review discusses the comet assay and summarizes research on non-ionizing EMF exposure and DNA/chromosomal damage. It describes both positive and negative findings across studies, noting no consistent overall pattern for radiofrequency radiation (RFR). The authors nonetheless conclude that under certain exposure…

Biological effects from electromagnetic field exposure and public exposure standards

Research RF Safe Research Library Jan 1, 2008

This review describes public concerns and scientific reports of non-thermal biological effects from low-intensity ELF and RF exposures. It lists multiple health endpoints reported to be associated with ELF and/or RF and highlights the BioInitiative Report’s conclusion that a reasonable suspicion of risk exists at…

Genetic damage in mammalian somatic cells exposed to radiofrequency radiation: a meta-analysis of data from 63 publications (1990-2005)

Research RF Safe Research Library Jan 1, 2008

A meta-analysis of 63 publications assessed whether radiofrequency (RF) radiation exposure is associated with genetic damage in mammalian somatic cells using multiple genotoxicity endpoints. Overall differences between RF-exposed and control conditions were reported as small, though statistically significant…

[Evaluation of the genotoxicity of the extremely low frequency-magnetic fields (ELF-MF) in workers exposed for professional reasons].

Research RF Safe Research Library Jan 1, 2007

This occupational study assessed whether extremely low frequency magnetic fields (ELF-MF) are associated with genotoxicity using cytogenetic assays in 109 workers. Comparisons across exposure strata, including a highest-exposed subgroup (TWA > 1 microT), found no significant differences in CA, SCE, or MN outcomes.…

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