Synthesis, biological evaluation, molecular docking, molecular dynamics simulation, and ADME studies of novel carbazole-aniline hybrids as cytotoxic agents.
Research
RF Safe Research Library
Jan 1, 2026
This study reports the design and synthesis of seven carbazole-aniline hybrids and evaluates their cytotoxicity in breast (MCF-7) and colon (SW480) cancer cell lines. Compound 5e was identified as the most potent in vitro candidate and was supported by docking and molecular dynamics results suggesting binding to…
Precision knockdown of EGFR gene expression using radio frequency electromagnetic energy.
Research
RF Safe Research Library
Jan 1, 2017
This study reports a technology that records a specific radiofrequency electromagnetic energy signal associated with EGFR siRNA and applies it to cells. The abstract describes reductions in EGFR mRNA and protein expression versus controls, with specificity assessed using RNA microarray and antibody dot blot array. It…