Effects of paternal 5G RFR exposure on health of male offspring mice
Research
RF Safe Research Library
Jan 1, 2025
This animal study examined whether paternal exposure to 4.9 GHz (5G) radiofrequency radiation affects male offspring in C57BL/6 mice. It reports increased anxiety-like behavior and reduced sperm quality in adult F1 males from exposed fathers, alongside reported LRGUK hypermethylation and reduced LRGUK expression in…
5G-exposed human skin cells do not respond with altered gene expression and methylation profiles
Research
RF Safe Research Library
Jan 1, 2025
This in vitro study exposed human skin cells (fibroblasts and keratinocytes) to 5G-band electromagnetic fields for 2 hours and 48 hours using a fully blinded design. Exposures were up to ten times permissible limits, with sham exposure as a negative control and UV exposure as a positive control. The study reports…
Exploring the impact of environmental factors on male reproductive health through epigenetics
Research
RF Safe Research Library
Jan 1, 2025
This narrative review discusses how environmental factors may affect male reproductive health through epigenetic mechanisms, including DNA methylation, histone modifications, chromatin remodeling, and non-coding RNA regulation. It reports that electromagnetic radiation, particularly from mobile phones and wireless…
Effect of electromagnetic field radiation on transcriptomic profile and DNA methylation level in pig conceptuses during the peri-implantation period
Research
RF Safe Research Library
Jan 1, 2025
This in vitro study exposed pig conceptuses (days 15–16 of pregnancy) to 50 Hz ELF-EMF for 2 hours and assessed transcriptomic and DNA methylation changes. The authors report altered expression of 21 protein-coding transcripts and an approximately 16-fold increase in genomic DNA methylation, with promoter methylation…
A Pilot Study Evaluating the Feasibility and Efficacy of an In-Home Resonance-Based Electromagnetic Field Protection Device on Improving Markers of Health and Cognitive Function Among a Sample of Healthy Adults.
Research
RF Safe Research Library
Jan 1, 2024
This single-arm 12-week pilot/feasibility study enrolled 25 relatively healthy adults to evaluate an in-home resonance-based EMF protection device (BluShield). The abstract reports high compliance and no adverse events, with modest improvements in self-reported health, several cognitive questionnaire domains, and…
Crosstalk between 6-methyladenine and 4-methylcytosine in exposed to extremely low-frequency electromagnetic field.
Research
RF Safe Research Library
Jan 1, 2024
This study examined prokaryotic DNA methylation (6mA and 4mC) and transcriptomes under different intensities of extremely low-frequency electromagnetic field (ELF-EMF) exposure. It reports motif-specific 6mA at 5'-GTACAG-3' and ELF-EMF-intensity-associated changes in spatial relationships among other 6mA sites,…
Exposure to the extremely low-frequency electromagnetic field induces changes in the epigenetic regulation of gene expression in the endometrium.
Research
RF Safe Research Library
Jan 1, 2024
This in vitro study exposed porcine endometrial slices from days 15–16 of pregnancy to a 50 Hz extremely low-frequency electromagnetic field for 2 hours. The authors report changes in several epigenetic-related markers, including DNA methylation machinery, histone-related measures (HDAC activity), global DNA…
Extremely low-frequency electromagnetic field exposure alters DNA methylation levels in the endometrium of pigs during the peri-implantation period.
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study exposed porcine endometrial slices from the peri-implantation period (days 15–16 of pregnancy) to 50 Hz ELF-EMF for 2 hours and assessed promoter DNA methylation in selected genes. The authors report increased methylation for EGR2, ID2, and PTGER4, decreased methylation for IL1RAP and NOS3, and no…