Effect of Electromagnetic Field on Proliferation and Migration of Fibroblasts and Keratinocytes: Implications in Wound Healing and Regeneration.
Research
RF Safe Research Library
Jan 1, 2024
This narrative review discusses reported effects of EMF, including low-frequency EMF (LF-EMF), on cell behaviors relevant to wound healing and on recovery processes after traumatic brain injury (TBI). It summarizes literature suggesting EMF can promote migration and proliferation of fibroblasts, keratinocytes, and…
Effect of rmEGF combined with ELF-EMF on promoting wound healing in rats.
Research
RF Safe Research Library
Jan 1, 2024
This randomized animal study evaluated whether recombinant murine EGF combined with ELF-EMF improves wound healing in rats. The combined ELF-EMF+rmEGF group showed better wound healing rates and more favorable histological features than comparison groups at multiple time points. All groups had complete wound closure…
Evaluation of Cell Migration and Cytokines Expression Changes under the Radiofrequency Electromagnetic Field on Wound Healing In Vitro Model.
Research
RF Safe Research Library
Jan 1, 2022
This in vitro study evaluated whether radiofrequency electromagnetic field (RF-EMF) exposure could influence wound-healing-related processes. The authors report increased keratinocyte migration and changes in expression of wound-healing genes, including MMPs, TIMPs, and pro/anti-inflammatory cytokines. The abstract…
Extremely low-frequency electromagnetic fields accelerates wound healing modulating MMP-9 and inflammatory cytokines.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study used a scratch wound model in human immortalized keratinocytes (HaCaT) to examine effects of extremely low-frequency electromagnetic fields (ELF-EMF). ELF-EMF exposure was reported to accelerate wound closure compared with sham and to increase inflammatory cytokine expression/release. The authors…
Effect of long-term exposure of mice to 900 MHz GSM radiation on experimental cutaneous candidiasis.
Research
RF Safe Research Library
Jan 1, 2017
This animal study examined whether long-term 900 MHz GSM-like microwave exposure affects experimentally induced cutaneous candidiasis in BALB/c mice. Exposed mice reportedly had delayed wound healing and higher Candida loads in skin lesions compared with unexposed mice. Following systemic Candida challenge, exposed…
Efficacy of 50 Hz electromagnetic fields on human epidermal stem cell transplantation seeded in collagen sponge scaffolds for wound healing in a murine model.
Research
RF Safe Research Library
Jan 1, 2017
This animal study evaluated whether 50 Hz EMF exposure enhances wound healing after transplantation of human epidermal stem cells (ESC) seeded in collagen sponge scaffolds. Thirty-six nude mice with full-thickness wounds were assigned to control, ESC-only, or ESC+EMF groups (50 Hz, 5 mT, 60 min/day for 20 days). The…
Effects of a continuous electromagnetic field on wound healing in human airway.
Research
RF Safe Research Library
Jan 1, 2015
This in vitro study exposed BEAS-2B human bronchial epithelial cells to a 1.8-GHz continuous EMF at SAR 1.0 W/kg and assessed wound-healing related endpoints. EMF exposure decreased cell migration in a scratch assay compared with controls. The authors report no cytotoxicity, no inhibition of proliferation, and no…