This RF Safe article argues that pulsed, low-frequency-modulated wireless radiofrequency exposures could disrupt voltage-gated ion channel timing (via the S4 voltage sensor), leading to altered immune-cell signaling, mitochondrial oxidative stress, and downstream innate immune activation and inflammation. It presents a mechanistic narrative linking small membrane-potential shifts to changes in calcium and proton channel behavior, then to mitochondrial reactive oxygen species and inflammatory pathways (e.g., cGAS–STING, TLR9, NLRP3). The post cites animal findings and a described 2025 mouse gene-expression study as supportive, but the piece itself is not a peer-reviewed study and some claims are presented as deterministic without providing full methodological details in the excerpt.

This rat study tested whether 2600 MHz radiofrequency field exposure interacts with indomethacin to affect gastric tissue. Both exposures alone were reported to increase oxidative stress and reduce antioxidant markers in the stomach. Co-exposure was reported to intensify oxidative stress, apoptosis, and histological gastric mucosal injury compared with either factor alone, consistent with a synergistic detrimental effect in this model.

This animal and in vitro study examined non-thermal 900 MHz RF-EMF exposure during prenatal and postnatal development at 0.08 and 0.4 W/kg SAR. The authors report changes consistent with altered neurodevelopment, including reduced BDNF, reduced in vivo cell proliferation, and disrupted synaptic balance in rat pup brain regions. In vitro, exposed neural stem cells showed increased apoptosis and DNA double-strand breaks and shifts in cell populations toward glial lineages. The authors conclude that regulatory-level 900 MHz exposure can disrupt key neurodevelopmental processes in rodents.

This exposure assessment measured RF power density across different floors of a high-rise university building using a spectrum analyser and log-periodic antenna. Power density decreased from the ground to the third floor but peaked on the fourth (top) floor. The 900 MHz band showed the highest reported power density (1.16E-03 W/m2), and the authors suggest higher-floor occupants may experience higher RF exposure from nearby communication towers.

This animal study examined short- and long-term 700 MHz (lower-band 5G) radiofrequency exposure in female Wistar rats, comparing control, sham, and exposed groups. It reports no DNA damage and no change in estrous cycle length, but increased ovarian oxidative stress markers in exposed animals. Long-term exposure was associated with ovarian histopathological alterations, while estradiol and progesterone stayed within normal ranges and testosterone increased slightly but significantly.

This animal study exposed juvenile and young adult Wistar rats to 5G (3.5 GHz) or 2G (900 MHz) radiofrequency fields (1.5 V/m) for 1–2 weeks and measured brown adipose tissue-related gene expression by RT-qPCR. The abstract reports significant downregulation of PRDM16 and C/EBP mRNA after 5G exposure, while UCP1-dependent thermogenesis markers were not significantly changed at the transcriptional level. The authors interpret these findings as a potential partial disruption of brown adipocyte differentiation and raise EMF safety concerns, while calling for further confirmatory research.

This systematic review and dose-response meta-analysis synthesizes human observational studies on radiofrequency EMF exposure and male fertility outcomes. It reports evidence of an association between RF exposure and poorer sperm parameters, including reduced quality, motility, and viability. The authors frame the findings as consistent with potential reproductive health risks and call for continued risk assessment and guideline development.