Risk factors for suboptimal target attainment of commonly used ß-lactam antibiotics in older adults: a prospective cohort study.
Research
RF Safe Research Library
Jan 1, 2026
This prospective observational pharmacokinetic study in geriatric inpatients (≥75 years) assessed whether standard IV dosing of amoxicillin-clavulanate and piperacillin-tazobactam achieved a 100% fT>MIC target. Target attainment was lower for amoxicillin-clavulanate than for piperacillin-tazobactam in this cohort.…