Electromagnetic field-mediated chitosan/gelatin/nano-hydroxyapatite and bone-derived scaffolds regulate the osteoblastic and chondrogenic phenotypes of adipose-derived stem cells to construct osteochondral tissue engineering niche in vitro.
Research
RF Safe Research Library
Jan 1, 2024
This in vitro study examined how electromagnetic field (EMF) coupling parameters and field direction interact with 2D versus 3D culture environments to influence adipose-derived stem cell (ADSC) proliferation and osteogenic/chondrogenic differentiation. The abstract reports different “optimal” magnetic flux densities…
High-specificity protection against radiation-induced bone loss by a pulsed electromagnetic field.
Research
RF Safe Research Library
Jan 1, 2022
This study reports a noninvasive pulsed-burst electromagnetic field (PEMF) approach intended to protect against radiotherapy-induced bone loss. A 15 Hz, 2 mT PEMF waveform is described as producing distinctive calcium oscillations in osteoblasts and inhibiting radiation-related bone loss while not affecting other…
Electromagnetic Fields Generated by the IteraCoil Device Differentiate Mesenchymal Stem Progenitor Cells Into the Osteogenic Lineage.
Research
RF Safe Research Library
Jan 1, 2022
This in vitro study exposed human adipose-derived mesenchymal stem progenitor cells to an alternating EMF generated by the IteraCoil device at 0.05 and 1 kHz. The authors report that EMF exposure was associated with osteoblastic differentiation in the absence of exogenous pro-osteogenic supplements, assessed by…
[Genic and non-genic regulation of low frequence pulsed electromagnetic fields on osteoblasts differentiation].
Research
RF Safe Research Library
Jan 1, 2016
This in vitro study exposed rat calvarial osteoblasts to 50 Hz, 0.6 mT pulsed electromagnetic fields for 1.5 hours and measured early differentiation-related markers over 0–12 hours. The abstract reports increased ALP activity at 3 hours and time-dependent changes in ALP, Runx2, and OSX transcription and Runx2/OSX…
[Effects of static magnetic field at different times on the proliferation and differentiation of osteoblasts in vitro].
Research
RF Safe Research Library
Jan 1, 2012
This in vitro study exposed newborn rat calvarial osteoblasts to a 3.9 mT static magnetic field for varying durations (0–4 hours). The authors report increased cell proliferation and markers of osteoblast differentiation and mineralization versus control, including higher ALP activity, calcium content, and…
[Time effect of sinusoidal electromagnetic field on enhancing the maturation and mineralization of osteoblasts in vitro].
Research
RF Safe Research Library
Jan 1, 2011
This in vitro study exposed newborn rat calvarial osteoblasts to 50 Hz sinusoidal electromagnetic fields at 1.8 mT for different daily exposure times (0.5–3.0 h). The authors report inhibited osteoblast proliferation at longer exposure times, alongside increased differentiation markers (ALP activity) and…