Archive

Electromagnetic field-mediated chitosan/gelatin/nano-hydroxyapatite and bone-derived scaffolds regulate the osteoblastic and chondrogenic phenotypes of adipose-derived stem cells to construct osteochondral tissue engineering niche in vitro.

This in vitro study examined how electromagnetic field (EMF) coupling parameters and field direction interact with 2D versus 3D culture environments to influence adipose-derived stem cell (ADSC) proliferation and osteogenic/chondrogenic differentiation. The abstract reports different “optimal” magnetic flux densities…

Hydrogel-hydroxyapatite-monomeric collagen type-I scaffold with low-frequency electromagnetic field treatment enhances osteochondral repair in rabbits.

This animal and in vitro study evaluated a composite osteochondral scaffold with bone marrow mesenchymal stem cells (BMSCs) combined with low-frequency electromagnetic field (EMF) stimulation. The authors report that EMF promoted BMSC proliferation and chondrogenic differentiation in vitro, partly via PI3K/AKT/mTOR…

Structural features of hydroxyapatite and carbonated apatite formed under the influence of ultrasound and microwave radiation and their effect on the bioactivity of the nanomaterials.

This study reports synthesizing hydroxyapatite and carbonate-substituted hydroxyapatite using ultrasound and microwave radiation as processing methods. The authors report that these physical factors produced calcium-deficient hydroxyapatite and B-type carbonated apatite and increased in vitro bioactivity compared…

Nanocrystalline hydroxyapatite bioceramic using microwave radiation: Synthesis and characterization.

This engineering/materials study synthesized nanocrystalline hydroxyapatite bioceramic powder using microwave radiation and then characterized the resulting material. The authors report highly crystalline HAp nanopowder with nanoscale size, mixed morphology, and elemental composition consistent with the HAp phase.…