This paper presents a methodological discussion about how to interpret exposure-response patterns and synthesize evidence in low-intensity RF-EMF research, focusing on animal cancer bioassays. It references an exchange around a systematic review on RF-EMF and cancer in experimental animals and critiques/considers approaches to statistical inference and evidence synthesis. The authors emphasize that methodological choices can materially influence carcinogenic hazard identification and argue for rigorous, evidence-based analysis in risk assessment.