Archive

The effects of electrical stimulation on neurons and glia of the central nervous system

This review synthesizes evidence on how direct current and alternating current electrical stimulation affect neurons and glia in the central nervous system, spanning basic research and clinical translation. It reports polarity- and parameter-dependent effects on axonal growth, along with immunomodulatory glial…

It is the Frequency that Matters: Effects of Electromagnetic Fields on the Release and Content of Extracellular Vesicles.

This preprint describes an in vitro bioreactor-based system to test whether electromagnetic/electrical stimulation affects extracellular vesicles (EVs). Using proteomics and single-vesicle flow cytometry, the authors report that stimulation at physiological current amplitudes can modulate EV content in a…

Comparison of 2 methods of non-invasive treatment between transcutaneous electrical stimulation and pulsed electromagnetic field stimulation as replacement of invasive manual acupuncture.

This study compared two non-invasive acupoint stimulation methods—TEAS and PEMF—as alternatives to manual acupuncture for recovery from exercise-induced muscle fatigue. Using 2 Hz stimulation (PEMF magnetic flux 30.92 mT), the authors report faster recovery of EMG median frequency and improved peak torque recovery in…

Sham Transcranial Magnetic Stimulation Using Electrical Stimulation of the Scalp.

This study describes development and validation of a sham rTMS approach that combines a matched sham coil (for look/sound) with scalp electrical stimulation (for sensation). In back-to-back comparisons, TMS-naïve participants reportedly could not tell active from sham, whereas experienced participants could. The…