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Behaviour and reproduction of Drosophila melanogaster exposed to 3.6 GHz radio-frequency electromagnetic fields

Research RF Safe Research Library Jan 1, 2025

This animal study assessed whether 3.6 GHz RF-EMF exposure affects behaviour and reproduction in adult Drosophila melanogaster, using micro-CT-based digital-twin dosimetry and numerical simulations. It reports no significant changes in locomotor activity after 5 days at 5.4–9 V/m and no effect on fecundity over 48 hours at the tested absorbed power. The authors note that effects could still be possible at other exposure levels or in different developmental stages.

Role of visual and non-visual opsins in blue light-induced neurodegeneration in Drosophila melanogaster

Research RF Safe Research Library Jan 1, 2025

This animal study used Drosophila knockout lines to examine whether visual (Rh1) versus non-visual (Rh7) opsins contribute to blue-light-associated neural damage. Flies were continuously exposed to 488 nm blue light from egg deposition to 20 days, and brain DNA damage and vacuolisation were assessed. The study reports greater DNA damage and neurodegeneration markers in Rh1 knockout flies than in wild-type or Rh7 knockout flies, and concludes Rh1 is a predominant mediator of blue-light-induced neurotoxicity in the fly CNS.

3.5GHz radiofrequency electromagnetic fields (RF-EMF) on metabolic disorders in Drosophila melanogaster

Research RF Safe Research Library Jan 1, 2025

This animal study used metabolomics to assess metabolic changes in male Drosophila melanogaster exposed to 3.5 GHz RF-EMF at 0.1, 1, and 10 W/m². It reports disruptions in four metabolic pathways and 34 differential metabolites, with significant decreases in several metabolites including GABA, glucose-6-phosphate, and AMP. The authors interpret the findings as suggesting RF-EMF-related metabolic disturbance, while noting no clear dose-dependent pattern.

Sensation of electric fields in the Drosophila melanogaster larva

Research RF Safe Research Library Jan 1, 2025

This animal study reports that Drosophila melanogaster larvae can sense electric fields and exhibit robust electrotaxis toward the cathode in controlled environments. The authors identify head-tip sensory neurons required for this behavior and report calcium-imaging evidence that Gr66a-positive neurons encode field strength and orientation. The work supports electrosensation as a functional sensory modality in Drosophila larvae and demonstrates measurable neural and behavioral responses to electric fields under the studied conditions.

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