Microglial Response to Inflammatory Stimuli Under Electromagnetic Field Exposure.
Research
RF Safe Research Library
Jan 1, 2025
This in vitro study examined whether extremely low frequency EMF exposure alters responses of TNF-α-stimulated human microglial cells (HMC3). Cells exposed to 2.5 or 5 Hz EMF for 3 minutes showed increased survival under high TNF-α conditions and reduced migration compared with TNF-α treatment alone. EMF also…
Modulation of inflammatory response by electromagnetic field in Neuronal and Microglial cells.
Research
RF Safe Research Library
Jan 1, 2025
This in vitro study examined whether low-frequency electromagnetic field (EMF) stimulation modulates inflammatory signaling in neuronal and microglial cell lines after induction of a pro-inflammatory state with TNF-α. The authors report reduced transcriptional expression of inflammatory target genes at 24 and 48…
Cancer on-target: Selective enhancement of 3-bromopyruvate action by an electromagnetic field in vitro.
Research
RF Safe Research Library
Jan 1, 2022
This in vitro study tested continuous or pulsed ELF electromagnetic field exposure in human cancer cells treated with the anticancer agent 3-bromopyruvate (3BP). The authors report that ELF-EMF enhanced 3BP anti-cancer activity, which they link to reduced TNFα secretion, p21/p27-associated G2/M arrest, and cancer…
Necroptosis triggered by ROS accumulation and Ca overload, partly explains the inflammatory responses and anti-cancer effects associated with 1Hz, 100 mT ELF-MF in vivo.
Research
RF Safe Research Library
Jan 1, 2021
This animal and in vitro study examined ELF magnetic field exposure in a mouse breast tumor model and a breast cancer cell line. The authors report tumor growth suppression and reduced expression of Ki-67, CD31, VEGFR2, and MMP-9 after exposure. They also report increased IFN-γ and TNF-α and increased…
Activation of TLR signalling regulates microwave radiation-mediated impairment of spermatogenesis in rat testis.
Research
RF Safe Research Library
Jan 1, 2018
This rat study examined whether microwave radiation affects Toll-like receptor (TLR) signaling in testis. The authors report increased TLR2-5 expression and elevated pro-inflammatory cytokines (IL-1β, IL-6, TNF-α) after microwave exposure. Key phosphorylated components of TLR signaling (including NF-κB p65) were also…
Microwave radiation induced oxidative stress, cognitive impairment and inflammation in brain of Fischer rats.
Research
RF Safe Research Library
Jan 1, 2012
This animal study exposed male Fischer-344 rats to 900 MHz or 1800 MHz microwave radiation for 30 days (2 h/day) and compared outcomes to sham exposure. The authors report significant cognitive impairment along with increased oxidative stress in brain tissue in exposed rats. They also report increased inflammatory…