Electromagnetic fields modulate neuronal membrane ionic currents through altered cellular calcium homeostasis.
Research
RF Safe Research Library
Jan 1, 2025
This experimental study used loose patch clamp recordings in coronal hippocampal slices to test effects of extremely low-frequency EMF exposure. A 50 Hz, 1 mT field applied for 60 minutes decreased inward and transient outward currents in CA1 pyramidal neuron membranes. Pharmacological manipulation of intracellular…
An ephaptic transmission model of CA3 pyramidal cells: an investigation into electric field effects.
Research
RF Safe Research Library
Jan 1, 2014
This paper presents a two-compartment computational model of CA3 pyramidal neurons to investigate how extracellular electric fields influence neuronal behavior via ephaptic transmission. The model is matched to subthreshold experimental responses at rest and used to analyze how DC and sinusoidal fields affect…
Role of cortical cell type and morphology in subthreshold and suprathreshold uniform electric field stimulation in vitro.
Research
RF Safe Research Library
Jan 1, 2009
This in vitro study examined how cortical neuron morphology and cell type relate to responses under subthreshold and suprathreshold uniform electric fields in rat motor cortex slices. The authors report that morphology correlates with subthreshold somatic polarization and that layer V pyramidal neurons are predicted…