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Showing results for: G2/M arrest

Enhanced Antiproliferative Activity of Docetaxel by Extremely Low Frequency Electromagnetic Fields in MCF-7 Breast Cancer Cells.

Research RF Safe Research Library Jan 1, 2025

This in vitro study tested whether extremely low-frequency electromagnetic fields (50 Hz, 20 mT) enhance docetaxel effects in MCF-7 breast cancer cells. The authors report that combining ELF-EMF with docetaxel produced a similar reduction in cell viability at a lower docetaxel concentration than docetaxel alone,…

P53 status, and G2/M cell cycle arrest, are determining factors in cell-death induction mediated by ELF-EMF in glioblastoma.

Research RF Safe Research Library Jan 1, 2023

This in vitro study tested ELF-EMF exposure in U87 and U251 glioblastoma cell lines and assessed apoptosis, cell-cycle distribution, cell size, and mRNA expression of cell-cycle genes. The authors report higher apoptosis induction and increased G2/M arrest in U87 compared with U251, alongside increased U87 cell size…

Cancer on-target: Selective enhancement of 3-bromopyruvate action by an electromagnetic field in vitro.

Research RF Safe Research Library Jan 1, 2022

This in vitro study tested continuous or pulsed ELF electromagnetic field exposure in human cancer cells treated with the anticancer agent 3-bromopyruvate (3BP). The authors report that ELF-EMF enhanced 3BP anti-cancer activity, which they link to reduced TNFα secretion, p21/p27-associated G2/M arrest, and cancer…

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