Synthesis, biological evaluation, molecular docking, molecular dynamics simulation, and ADME studies of novel carbazole-aniline hybrids as cytotoxic agents.
Research
RF Safe Research Library
Jan 1, 2026
This study reports the design and synthesis of seven carbazole-aniline hybrids and evaluates their cytotoxicity in breast (MCF-7) and colon (SW480) cancer cell lines. Compound 5e was identified as the most potent in vitro candidate and was supported by docking and molecular dynamics results suggesting binding to…
Gene Expression Analysis in Human Peripheral Blood Cells after 900 MHz RF-EMF Short-Term Exposure.
Research
RF Safe Research Library
Jan 1, 2018
This ex vivo/in vitro study exposed peripheral blood cells from five human donors to a 900 MHz continuous-wave RF-EMF for up to 90 minutes (average SAR 9.3 W/kg). After false discovery rate adjustment, the authors report no EMF-specific gene expression changes on microarray analysis. Although low-stringency analysis…
Effect of long-term exposure of mice to 900 MHz GSM radiation on experimental cutaneous candidiasis.
Research
RF Safe Research Library
Jan 1, 2017
This animal study examined whether long-term 900 MHz GSM-like microwave exposure affects experimentally induced cutaneous candidiasis in BALB/c mice. Exposed mice reportedly had delayed wound healing and higher Candida loads in skin lesions compared with unexposed mice. Following systemic Candida challenge, exposed…
Effect of long-term exposure to mobile phone radiation on alpha-Int1 gene sequence of Candida albicans.
Research
RF Safe Research Library
Jan 1, 2016
This in vitro study evaluated whether long-term 900 MHz radiation exposure induces mutations in the alpha-Int1 gene of Candida albicans. Yeast samples were exposed for 10 to 490 hours at 4°C and compared with unexposed controls. Sequencing of the PCR-amplified alpha-Int1 fragment found no mutations in exposed samples…